Literature DB >> 30229469

Severe pulmonary haemorrhage syndrome in leptospirosis in a returning traveller.

Andreas Schönfeld1, B Jensen2, H M Orth2, D Tappe3, T Feldt2, D Häussinger2.   

Abstract

Clinical presentation of leptospirosis ranges from asymptomatic infection to fulminant, life-threatening disease. Pulmonary involvement in terms of severe pulmonary haemorrhage syndrome (SPHS) has recently become a more frequently reported facet of leptospirosis and correlates with high mortality rates. It has not yet been described in returning German travellers. We present a case of a healthy young man developing massive pulmonary haemorrhage and severe ARDS requiring mechanical ventilation and high-dose catecholamines after travelling to Indonesia. Leptospirosis was verified by blood PCR as well as serology and treated with high-dose, intravenous penicillin. Outcome was favourable, the patient recovered completely. Leptospirosis and SPHS should be taken into account as an emerging infectious disease in patients with fever and lung involvement.

Entities:  

Keywords:  Emerging infectious disease; Leptospirosis; Severe pulmonary haemorrhage syndrome; Travel medicine

Mesh:

Substances:

Year:  2018        PMID: 30229469     DOI: 10.1007/s15010-018-1220-7

Source DB:  PubMed          Journal:  Infection        ISSN: 0300-8126            Impact factor:   3.553


  17 in total

Review 1.  Pulmonary complications of leptospirosis.

Authors:  Carlos Roberto Ribeiro Carvalho; Eduardo P Bethlem
Journal:  Clin Chest Med       Date:  2002-06       Impact factor: 2.878

2.  Predictors of lethality in severe leptospirosis in urban Brazil.

Authors:  Anne S Spichler; Pedro J Vilaça; Daniel A Athanazio; Jose O M Albuquerque; Marcia Buzzar; Bronislawa Castro; Antonio Seguro; Joseph M Vinetz
Journal:  Am J Trop Med Hyg       Date:  2008-12       Impact factor: 2.345

Review 3.  Emergence, control and re-emerging leptospirosis: dynamics of infection in the changing world.

Authors:  R A Hartskeerl; M Collares-Pereira; W A Ellis
Journal:  Clin Microbiol Infect       Date:  2011-04       Impact factor: 8.067

4.  High efficacy of bolus methylprednisolone in severe leptospirosis: a descriptive study in Sri Lanka.

Authors:  Senanayake A M Kularatne; B D Sudhara S Budagoda; V Kapila D de Alwis; W M R Sujantha Wickramasinghe; J M Ruwanthi P Bandara; L P Manoji M K Pathirage; G Rohitha R D K Gamlath; Thusitha J Wijethunga; W A Thilak A Jayalath; Chandrika Jayasinghe; Vasanthi Pinto; Praneetha Somaratne; P V Ranjith Kumarasiri
Journal:  Postgrad Med J       Date:  2010-11-24       Impact factor: 2.401

5.  Clinicopathological and immunohistochemical features of the severe pulmonary form of leptospirosis.

Authors:  João José Pereira Silva; Marcos Olivier Dalston; Jorge Eduardo Manhães Carvalho; Sérgio Setúbal; Janice Mery Chiarino Oliveira; Martha Maria Pereira
Journal:  Rev Soc Bras Med Trop       Date:  2002 Jul-Aug       Impact factor: 1.581

6.  Severe Pulmonary Involvement in Leptospirosis: Alternate antibiotics and systemic steroids.

Authors:  B Jayakrishnan; Fatma Ben Abid; Abdullah Balkhair; Juma K Alkaabi; Omar A Al-Rawas; Jojy George; Khalfan Al-Zeedy
Journal:  Sultan Qaboos Univ Med J       Date:  2013-05-09

7.  Acute Respiratory Distress Syndrome Manifested by Leptospirosis Successfully Teated by Extracorporeal Membrane Oxygenation (ECMO).

Authors:  Chen-Yi Liao; Ren-Jy Ben; Hau-Ming Wu; Shih-Kun Chang; Mei-Yu Liu; Hsien-Kuo Chin; Yen-Cheng Yeh
Journal:  Intern Med       Date:  2015-11-15       Impact factor: 1.271

8.  Pulmonary involvement predicts mortality in severe leptospirosis patients.

Authors:  Eko Budiono; Bambang Sigit Riyanto; Barmawi Hisyam; Anggoro Budi Hartopo
Journal:  Acta Med Indones       Date:  2009-01

9.  A Universal Vaccine against Leptospirosis: Are We Going in the Right Direction?

Authors:  André Alex Grassmann; Jéssica Dias Souza; Alan John Alexander McBride
Journal:  Front Immunol       Date:  2017-03-09       Impact factor: 7.561

10.  Leptospirosis-associated catastrophic respiratory failure supported by extracorporeal membrane oxygenation.

Authors:  Tamara Cantwell; Andrés Ferre; Nicolette Van Sint Jan; Rodrigo Blamey; Jorge Dreyse; Cristian Baeza; Rodrigo Diaz; Tomás Regueira
Journal:  J Artif Organs       Date:  2017-10-10       Impact factor: 1.731

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  2 in total

Review 1.  Leptospirosis: a neglected tropical zoonotic infection of public health importance-an updated review.

Authors:  Krishnan Baby Karpagam; Balasubramanian Ganesh
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2020-01-02       Impact factor: 3.267

2.  Pericarditis as a cardiac manifestation of acute leptospirosis.

Authors:  M Zechel; M Franz; M Baier; S Hagel; B T Schleenvoigt
Journal:  Infection       Date:  2020-08-10       Impact factor: 3.553

  2 in total

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