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Literature DB >> 23862041

Severe Pulmonary Involvement in Leptospirosis: Alternate antibiotics and systemic steroids.

B Jayakrishnan¹, Fatma Ben Abid, Abdullah Balkhair, Juma K Alkaabi, Omar A Al-Rawas, Jojy George, Khalfan Al-Zeedy.

Abstract

Pulmonary complications in leptospirosis, though common, are often unrecognized in a non-endemic area. We report here a patient with leptospirosis and severe pulmonary involvement who was treated with meropenem (1 g every 8 hours), moxifloxacin (400 mg once daily), and high doses of corticosteroids. Systemic steroids were continued for 3 months because of persistent pulmonary lesions.

Entities: Chemical Disease Species

Keywords: Case report; Human ARDS; Leptospirosis; Oman; Steroids

Year: 2013 PMID： 23862041 PMCID： PMC3706125 DOI： 10.12816/0003241

Source DB: PubMed Journal: Sultan Qaboos Univ Med J ISSN： 2075-051X

17 in total

1. Leptospirosis of the lung: high-resolution computed tomography findings in five patients.

Authors: Edson Marchiori; Nestor L Müller
Journal: J Thorac Imaging Date: 2002-04 Impact factor: 3.000

Review 2. Pulmonary complications of leptospirosis.

Authors: Carlos Roberto Ribeiro Carvalho; Eduardo P Bethlem
Journal: Clin Chest Med Date: 2002-06 Impact factor: 2.878

3. Anicteric leptospirosis-associated severe pulmonary hemorrhagic syndrome: a case series study.

Authors: Stelios F Assimakopoulos; Fotini Fligou; Markos Marangos; Anastasia Zotou; Aristea Psilopanagioti; Kriton S Filos
Journal: Am J Med Sci Date: 2012-10 Impact factor: 2.378

4. Pulmonary radiographic findings in 118 leptospirosis patients.

Authors: Wiwatana Tanomkiat; Pongpan Poonsawat
Journal: Southeast Asian J Trop Med Public Health Date: 2005-09 Impact factor: 0.267

5. Acute lung injury and leptospirosis.

Authors: R J Ramachandran
Journal: Br J Anaesth Date: 2007-07 Impact factor: 9.166

6. An open randomized controlled trial of desmopressin and pulse dexamethasone as adjunct therapy in patients with pulmonary involvement associated with severe leptospirosis.

Authors: K Niwattayakul; S Kaewtasi; S Chueasuwanchai; S Hoontrakul; S Chareonwat; C Suttinont; K Phimda; W Chierakul; S Silpasakorn; Y Suputtamongkol
Journal: Clin Microbiol Infect Date: 2009-09-02 Impact factor: 8.067

Review 5. Role of Plasmapheresis and Extracorporeal Membrane Oxygenation in the Treatment of Leptospirosis Complicated with Pulmonary Hemorrhages.

Authors: C L Fonseka; S Lekamwasam
Journal: J Trop Med Date: 2018-12-02

5 in total

Severe Pulmonary Involvement in Leptospirosis: Alternate antibiotics and systemic steroids.

1. Leptospirosis of the lung: high-resolution computed tomography findings in five patients.

Review 2. Pulmonary complications of leptospirosis.

3. Anicteric leptospirosis-associated severe pulmonary hemorrhagic syndrome: a case series study.

4. Pulmonary radiographic findings in 118 leptospirosis patients.

5. Acute lung injury and leptospirosis.

6. An open randomized controlled trial of desmopressin and pulse dexamethasone as adjunct therapy in patients with pulmonary involvement associated with severe leptospirosis.

7. Pulmonary leptospirosis: an excellent response to bolus methylprednisolone.

8. The role of glucocorticoid pulse therapy in pulmonary involvement in leptospirosis.

Review 9. Antimicrobial therapy of leptospirosis.

10. Clinicopathological and immunohistochemical features of the severe pulmonary form of leptospirosis.

1. Complicated Weil Disease.

2. Specific CD4+ T-Cell Reactivity and Cytokine Release in Different Clinical Presentations of Leptospirosis.

3. Severe pulmonary haemorrhage syndrome in leptospirosis in a returning traveller.

4. Leptospirosis-Associated Severe Pulmonary Hemorrhagic Syndrome with Lower Back Pain as an Initial Symptom.

Review 5. Role of Plasmapheresis and Extracorporeal Membrane Oxygenation in the Treatment of Leptospirosis Complicated with Pulmonary Hemorrhages.