Noah E Atwi1, David L Smith1, Carson D Flores2, Ekta Dharaiya3, Raman Danrad1, Avinash Kambadakone4, Aran M Toshav5. 1. Department of Radiology, LSU Health Sciences Center New Orleans, 1542 Tulane Avenue, New Orleans, LA, 70112, USA. 2. School of Medicine, LSU Health Sciences Center New Orleans, 1542 Tulane Avenue, New Orleans, LA, 70112, USA. 3. Philips Healthcare, 595 Miner Road, Highland Heights, OH, 44143, USA. 4. Division of Abdominal Imaging and Intervention, Massachusetts General Hospital, 55 Fruit Street, Boston, MA, 02114, USA. 5. Department of Radiology, LSU Health Sciences Center New Orleans, 1542 Tulane Avenue, New Orleans, LA, 70112, USA. atosha@lsuhsc.edu.
Abstract
PURPOSE: To determine the feasibility of performing dual-energy CT with a single-source spectral detector system in obese patients. MATERIALS AND METHODS: Retrospective, IRB-approved review of 28 patients weighing ≥ 270 lbs (122 kg) who underwent CT of the abdomen on a single-source spectral detector system was performed. Two blinded, independent radiologists rated relative preference between conventional CT images taken at 120 kVp (CCT120) and monoenergetic 70 keV equivalent (MonoE70) as well as iodine map image quality in the spleen, pancreas, kidneys, and liver. Signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) were compared between conventional CT and MonoE70 images and correlated with body habitus markers of weight, height, and abdominal diameter. RESULTS: MonoE70 images were preferred by radiologists 100% of the time (1-sample t test, p < 0.0001) over conventional CCT120 images. Noise was significantly lower; SNR and CNR were significantly higher in MonoE70 images than in CCT120 images (paired t tests, p < 0.0001). Mean iodine map rating (scale 1-5) was 4.54 ± 0.58, denoting near homogenous and complete iodine mapping through the spleen, pancreas, kidneys, and liver for the majority of patients. Body habitus markers were not significantly correlated with image preference score; noise; MonoE70 SNR; MonoE70 CNR; change in noise, SNR, or CNR from CCT120 to MonoE70, or iodine map quality; ordinal and linear regression, p = 0.2547, p = 0.6837, p = 0.1888, p = 0.5489, p = 0.9830, p = 0.8849, p = 0.8741, p = 0.1522, respectively. CONCLUSION: The single-source spectral detector implementation of dual-energy CT provides viable, high-quality imaging for obese patients.
PURPOSE: To determine the feasibility of performing dual-energy CT with a single-source spectral detector system in obesepatients. MATERIALS AND METHODS: Retrospective, IRB-approved review of 28 patients weighing ≥ 270 lbs (122 kg) who underwent CT of the abdomen on a single-source spectral detector system was performed. Two blinded, independent radiologists rated relative preference between conventional CT images taken at 120 kVp (CCT120) and monoenergetic 70 keV equivalent (MonoE70) as well as iodine map image quality in the spleen, pancreas, kidneys, and liver. Signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) were compared between conventional CT and MonoE70 images and correlated with body habitus markers of weight, height, and abdominal diameter. RESULTS:MonoE70 images were preferred by radiologists 100% of the time (1-sample t test, p < 0.0001) over conventional CCT120 images. Noise was significantly lower; SNR and CNR were significantly higher in MonoE70 images than in CCT120 images (paired t tests, p < 0.0001). Mean iodine map rating (scale 1-5) was 4.54 ± 0.58, denoting near homogenous and complete iodine mapping through the spleen, pancreas, kidneys, and liver for the majority of patients. Body habitus markers were not significantly correlated with image preference score; noise; MonoE70 SNR; MonoE70 CNR; change in noise, SNR, or CNR from CCT120 to MonoE70, or iodine map quality; ordinal and linear regression, p = 0.2547, p = 0.6837, p = 0.1888, p = 0.5489, p = 0.9830, p = 0.8849, p = 0.8741, p = 0.1522, respectively. CONCLUSION: The single-source spectral detector implementation of dual-energy CT provides viable, high-quality imaging for obesepatients.
Authors: Anushri Parakh; Chansik An; Simon Lennartz; Prabhakar Rajiah; Benjamin M Yeh; Frank J Simeone; Dushyant V Sahani; Avinash R Kambadakone Journal: Radiographics Date: 2021-02-19 Impact factor: 5.333