Markus Bauder1, Arthur Schmidt2, Karel Caca1. 1. Department of Gastroenterology and Oncology, Klinikum Ludwigsburg, Ludwigsburg, Germany. 2. Department of Gastroenterology, Medical Center, University of Freiburg, Freiburg im Breisgau, Baden-Württemberg, Germany.
Abstract
BACKGROUND: Endoscopic resections in the duodenum harbor a significant risk of complications. The full-thickness resection device (FTRD) has shown favorable results concerning efficacy and safety in the resection of colorectal lesions. Data of its use in the duodenum are limited to a single, small case series (n = 4). METHODS: Data of all consecutive patients scheduled for endoscopic full-thickness resection (EFTR) of duodenal lesions by FTRD in our institution were collected and analyzed retrospectively. Primary endpoint was technical success. RESULTS: Between March 2014 and June 2017 EFTR of a duodenal lesion was planned in a total of 20 patients. Overall technical success was 17/20 (85.0%). Indication for EFTR was: adenomas (n = 13, seven treatment naïve, six pretreated), subepithelial tumors (n = 5) and T1 adenocarcinoma (n = 1). The FTRD could be advanced to the lesion in 19/20 cases (95.0%). R0-resection rate was 12/19 (63.2%). During follow-up after 3 and 12 months there were two recurrent adenomas that were successfully re-resected by FTRD. Minor bleedings occurred at the first postinterventional day in 3/19 (15.8%). There were no major bleedings and perforations. CONCLUSION: This study confirmed the feasibility of duodenal EFTR and indicates good efficacy and safety. Larger studies are needed to further investigate this novel technique.
BACKGROUND: Endoscopic resections in the duodenum harbor a significant risk of complications. The full-thickness resection device (FTRD) has shown favorable results concerning efficacy and safety in the resection of colorectal lesions. Data of its use in the duodenum are limited to a single, small case series (n = 4). METHODS: Data of all consecutive patients scheduled for endoscopic full-thickness resection (EFTR) of duodenal lesions by FTRD in our institution were collected and analyzed retrospectively. Primary endpoint was technical success. RESULTS: Between March 2014 and June 2017 EFTR of a duodenal lesion was planned in a total of 20 patients. Overall technical success was 17/20 (85.0%). Indication for EFTR was: adenomas (n = 13, seven treatment naïve, six pretreated), subepithelial tumors (n = 5) and T1 adenocarcinoma (n = 1). The FTRD could be advanced to the lesion in 19/20 cases (95.0%). R0-resection rate was 12/19 (63.2%). During follow-up after 3 and 12 months there were two recurrent adenomas that were successfully re-resected by FTRD. Minor bleedings occurred at the first postinterventional day in 3/19 (15.8%). There were no major bleedings and perforations. CONCLUSION: This study confirmed the feasibility of duodenal EFTR and indicates good efficacy and safety. Larger studies are needed to further investigate this novel technique.
Authors: Alexander Perez; John R Saltzman; David L Carr-Locke; David C Brooks; Robert T Osteen; Michael J Zinner; Stanley W Ashley; Edward E Whang Journal: J Gastrointest Surg Date: 2003 May-Jun Impact factor: 3.452
Authors: Scott B Fanning; Michael J Bourke; Stephen J Williams; Adrian Chung; Viraj C Kariyawasam Journal: Gastrointest Endosc Date: 2012-02-03 Impact factor: 9.427
Authors: Krishnavel V Chathadi; Mouen A Khashab; Ruben D Acosta; Vinay Chandrasekhara; Mohamad A Eloubeidi; Ashley L Faulx; Lisa Fonkalsrud; Jenifer R Lightdale; John R Salztman; Aasma Shaukat; Amy Wang; Brooks D Cash; John M DeWitt Journal: Gastrointest Endosc Date: 2015-08-07 Impact factor: 9.427
Authors: Arthur Schmidt; Peter Bauerfeind; Christoph Gubler; Michael Damm; Markus Bauder; Karel Caca Journal: Endoscopy Date: 2015-03-12 Impact factor: 10.093
Authors: Yang Won Min; Byung-Hoon Min; Eun Ran Kim; Jun Haeng Lee; Poong-Lyul Rhee; Jong Chul Rhee; Jae J Kim Journal: Dig Dis Sci Date: 2013-05-22 Impact factor: 3.199
Authors: Irmengard Krutzenbichler; Markus Dollhopf; Helmut Diepolder; Andreas Eigler; Martin Fuchs; Simon Herrmann; Gerhard Kleber; Björn Lewerenz; Christoph Kaiser; Tilman Lilje; Timo Rath; Ayman Agha; Francesco Vitali; Claus Schäfer; Wolfgang Schepp; Felix Gundling Journal: Surg Endosc Date: 2020-07-09 Impact factor: 4.584
Authors: Maxime Amoyel; Arthur Belle; Marion Dhooge; Einas Abou Ali; Rachel Hallit; Frederic Prat; Anthony Dohan; Benoit Terris; Stanislas Chaussade; Romain Coriat; Maximilien Barret Journal: Endosc Int Open Date: 2022-01-14