BACKGROUND: Adverse skin reactions to skin care products have been increasing in recent years. However, to date, these reactions have not been well characterized. OBJECTIVE: To describe the symptoms, clinical signs and frequency of adverse cutaneous reactions to skin care products on the face in males vs females of various ages. PATIENTS AND METHODS: All outpatients diagnosed with adverse cutaneous reactions to skin care products on the face examined by dermatologists at the Dermatology Hospital of South Medical University between November 1, 2016 and October 31, 2017, employing a questionnaire and an interview, were eligible. The associations of adverse cutaneous reactions with age and sex were analysed. RESULTS: A total of 433 outpatients, accounting for 0.12% of all outpatients, were assessed. Of these, 223 patients, including 204 females and 19 males, aged 4 to 75 years, were eventually diagnosed with adverse reactions to skin care products on the face. Eighty-two per cent of patients experienced pruritus, 80% showed erythema, and 48% showed visible swelling. The incidence rates of both xerosis and oedema correlated positively with age, whereas acne-like lesions were negatively associated with age, but not with sex. CONCLUSIONS: Our results indicate that pruritus, xerosis and erythema are common adverse cutaneous reactions to facial skin care products. These reactions vary with age, but not with sex. Vigorous safety testing should precede the marketing of skin care products.
BACKGROUND: Adverse skin reactions to skin care products have been increasing in recent years. However, to date, these reactions have not been well characterized. OBJECTIVE: To describe the symptoms, clinical signs and frequency of adverse cutaneous reactions to skin care products on the face in males vs females of various ages. PATIENTS AND METHODS: All outpatients diagnosed with adverse cutaneous reactions to skin care products on the face examined by dermatologists at the Dermatology Hospital of South Medical University between November 1, 2016 and October 31, 2017, employing a questionnaire and an interview, were eligible. The associations of adverse cutaneous reactions with age and sex were analysed. RESULTS: A total of 433 outpatients, accounting for 0.12% of all outpatients, were assessed. Of these, 223 patients, including 204 females and 19 males, aged 4 to 75 years, were eventually diagnosed with adverse reactions to skin care products on the face. Eighty-two per cent of patients experienced pruritus, 80% showed erythema, and 48% showed visible swelling. The incidence rates of both xerosis and oedema correlated positively with age, whereas acne-like lesions were negatively associated with age, but not with sex. CONCLUSIONS: Our results indicate that pruritus, xerosis and erythema are common adverse cutaneous reactions to facial skin care products. These reactions vary with age, but not with sex. Vigorous safety testing should precede the marketing of skin care products.
Authors: Viviane Maria Rocha Martins; Antônio Renê Diógenes de Sousa; Natália de Carvalho Portela; Celina Aguiar Frota Tigre; Lucidi Maria Saraiva Gonçalves; Rômulo José de Lucena Castro Filho Journal: An Bras Dermatol Date: 2012 Jul-Aug Impact factor: 1.896
Authors: M Q Man; S J Xin; S P Song; S Y Cho; X J Zhang; C X Tu; K R Feingold; P M Elias Journal: Skin Pharmacol Physiol Date: 2009-07-31 Impact factor: 3.479
Authors: Mark Rinnerthaler; Jutta Duschl; Peter Steinbacher; Manuel Salzmann; Johannes Bischof; Markus Schuller; Herbert Wimmer; Thomas Peer; Johann W Bauer; Klaus Richter Journal: Exp Dermatol Date: 2013-05 Impact factor: 3.960
Authors: T Hasan; T Rantanen; K Alanko; R J Harvima; R Jolanki; K Kalimo; A Lahti; K Lammintausta; A I Lauerma; A Laukkanen; T Luukkaala; R Riekki; K Turjanmaa; E Varjonen; A-M Vuorela Journal: Contact Dermatitis Date: 2005-07 Impact factor: 6.600
Authors: F Xu; S Yan; M Wu; F Li; Q Sun; W Lai; X Shen; N Rahhali; C Taieb; J Xu Journal: J Eur Acad Dermatol Venereol Date: 2012-07-27 Impact factor: 6.166
Authors: Xiaohua Wang; Yunzhi Su; Baoqing Zheng; Si Wen; Dan Liu; Li Ye; Yunling Yan; Peter M Elias; Bin Yang; Mao-Qiang Man Journal: J Cosmet Dermatol Date: 2019-08-28 Impact factor: 2.696
Authors: S J Nisbet; D Targett; A V Rawlings; K Qian; X Wang; C B Lin; M A Thompson; P A Bulsara; D J Moore Journal: Int J Cosmet Sci Date: 2019-12 Impact factor: 2.970