Literature DB >> 30203319

Impact of sphincter lesions and delayed sphincter repair on sacral neuromodulation treatment outcomes for faecal incontinence: results from a Finnish national cohort study.

Jaan Kirss1,2, Tarja Pinta3, Tero Rautio4, Pirita Varpe5, Matti Kairaluoma6, Marja Hyöty7, Saija Hurme8, Camilla Böckelman9, Valtteri Kairaluoma6, Sinikka Salmenkylä9, Mikael Victorzon8,10.   

Abstract

PURPOSE: The aim of this multicentre study was to analyse the effects of patent sphincter lesions and previous sphincter repair on the results of sacral neuromodulation (SNM) treatment on patients with faecal incontinence (FI).
METHODS: Patients examined by endoanal ultrasound (EAUS) with FI as the indication for SNM treatment were included in the study. Data was collected from all the centres providing SNM treatment in Finland and analysed for differences in treatment outcomes.
RESULTS: A total of 237 patients treated for incontinence with SNM had been examined by EAUS. Of these patients, 33 had a history of previous delayed sphincter repair. A patent sphincter lesion was detected by EAUS in 128 patients. The EAUS finding did not influence the SNM test phase outcome (p = 0.129) or the final treatment outcome (p = 0.233). Patient's history of prior sphincter repair did not have a significant effect on the SNM test (p = 0.425) or final treatment outcome (p = 0.442).
CONCLUSIONS: Results of our study indicate that a sphincter lesion or previous sphincter repair has no significant effect on the outcome of SNM treatment. Our data suggests that delayed sphincter repair prior to SNM treatment initiation for FI is not necessary.

Entities:  

Keywords:  Anal sphincter repair; Endoanal ultrasound; Faecal incontinence; Obstetric anal sphincter injury; Sacral neuromodulation

Mesh:

Year:  2018        PMID: 30203319     DOI: 10.1007/s00384-018-3161-0

Source DB:  PubMed          Journal:  Int J Colorectal Dis        ISSN: 0179-1958            Impact factor:   2.571


  30 in total

1.  Bladder pacemaker: scientific basis and clinical future.

Authors:  E A Tanagho; R A Schmidt
Journal:  Urology       Date:  1982-12       Impact factor: 2.649

2.  Anal incontinence and quality of life following obstetric anal sphincter injury.

Authors:  Ranitha Kumar; Chun Ooi; Anthony Nicoll
Journal:  Arch Gynecol Obstet       Date:  2011-07-29       Impact factor: 2.344

3.  Outcome of obstetric anal sphincter injuries in terms of persisting endoanal ultrasonographic defects and defecatory symptoms.

Authors:  Eefje J Oude Lohuis; Ellen Everhardt
Journal:  Int J Gynaecol Obstet       Date:  2014-04-03       Impact factor: 3.561

4.  A retrospective review of 1495 patients with obstetric anal sphincter injuries referred for assessment of function and endoanal ultrasonography.

Authors:  G P Thomas; L E Gould; F Casunuran; D A Kumar
Journal:  Int J Colorectal Dis       Date:  2017-07-07       Impact factor: 2.571

Review 5.  Obstetric anal sphincter injury: incidence, risk factors, and management.

Authors:  Thomas C Dudding; Carolynne J Vaizey; Michael A Kamm
Journal:  Ann Surg       Date:  2008-02       Impact factor: 12.969

6.  Sacral nerve stimulation for fecal incontinence: external anal sphincter defect vs. intact anal sphincter.

Authors:  Miranda K Y Chan; Joe J Tjandra
Journal:  Dis Colon Rectum       Date:  2008-05-17       Impact factor: 4.585

7.  Prevalence of faecal incontinence in adults aged 30 years or more in general population.

Authors:  P Aitola; K Lehto; R Fonsell; H Huhtala
Journal:  Colorectal Dis       Date:  2009-04-10       Impact factor: 3.788

Review 8.  Vaginal childbirth and pelvic floor disorders.

Authors:  Hafsa U Memon; Victoria L Handa
Journal:  Womens Health (Lond)       Date:  2013-05

9.  Sacral neuromodulation in patients with faecal incontinence: results of the first 100 permanent implantations.

Authors:  J Melenhorst; S M Koch; O Uludag; W G van Gemert; C G Baeten
Journal:  Colorectal Dis       Date:  2007-05-17       Impact factor: 3.788

10.  Functional and quality of life outcomes following obstetric anal sphincter injury (OASI): does the grade of injury affect outcomes?

Authors:  Lisa Ramage; Clarence Yen; Shengyang Qiu; Constantinos Simillis; Christos Kontovounisios; Paris Tekkis; Emile Tan
Journal:  Int Urogynecol J       Date:  2017-05-18       Impact factor: 2.894

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  2 in total

1.  Tools for fecal incontinence assessment: lessons for inflammatory bowel disease trials based on a systematic review.

Authors:  Ferdinando D'Amico; Steven D Wexner; Carolynne J Vaizey; Célia Gouynou; Silvio Danese; Laurent Peyrin-Biroulet
Journal:  United European Gastroenterol J       Date:  2020-07-17       Impact factor: 4.623

2.  Therapeutic Potential of Ultrasound Neuromodulation in Decreasing Neuropathic Pain: Clinical and Experimental Evidence.

Authors:  Iván Pérez-Neri; Alberto González-Aguilar; Hugo Sandoval; Carlos Pineda; Camilo Ríos
Journal:  Curr Neuropharmacol       Date:  2021       Impact factor: 7.363

  2 in total

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