Literature DB >> 17509049

Sacral neuromodulation in patients with faecal incontinence: results of the first 100 permanent implantations.

J Melenhorst1, S M Koch, O Uludag, W G van Gemert, C G Baeten.   

Abstract

OBJECTIVE: Faecal incontinence (FI) is a socially devastating problem. Sacral nerve modulation (SNM) has proven its place in the treatment of patients with FI. In this study, the first 100 definitive SNM implants in a single centre have been evaluated prospectively.
METHOD: Patients treated between March 2000 and May 2005 were included. Faecal incontinence was defined as at least one episode of involuntary faecal loss per week confirmed by a 3-week bowel habit diary. Patients were eligible for implantation of a permanent SNM when showing at least a 50% reduction in incontinence episodes or days during ambulatory test stimulation. Preoperative workup consisted of an X-defaecography, pudendal nerve terminal motor latency measurement, endo-anal ultrasound and anal manometry. The follow-up visits for the permanent implanted patients were scheduled at 1, 3, 6 and 12 months and annually thereafter. The bowel habit diary and anal manometry were repeated postoperatively during the follow-up visits.
RESULTS: A total of 134 patients were included and received a subchronic test stimulation. One hundred patients (74.6%) had a positive test stimulation and received a definitive SNM implantation. The permanent implantation group consisted of 89 women and 11 men. The mean age was 55 years (range 26-75). The mean follow-up was 25.5 months (range 2.5-63.2). The mean number of incontinence episodes decreased significantly during the test stimulation (baseline, 31.3; test, 4.4; P < 0.0001) and at follow-up (36 months postoperatively, 4.8; P < 0.0001). There was no significant change in the mean anal resting pressure. The squeeze pressures were significantly higher at 6 months (109.8 mmHg; P = 0.03), 12 months (114.1 mmHg; P = 0.02) and 24 months postoperatively (113.5 mmHg; P = 0.007). The first sensation, urge and maximum tolerable volume did not change significantly. Twenty-one patients were considered late failures and received further treatment.
CONCLUSION: Sacral neuromodulation is an effective treatment for FI. The medium-term results were satisfying.

Entities:  

Mesh:

Year:  2007        PMID: 17509049     DOI: 10.1111/j.1463-1318.2007.01241.x

Source DB:  PubMed          Journal:  Colorectal Dis        ISSN: 1462-8910            Impact factor:   3.788


  30 in total

1.  Meta-analysis: sacral nerve stimulation versus conservative therapy in the treatment of faecal incontinence.

Authors:  Emile Tan; Nye-Thane Ngo; Ara Darzi; Michael Shenouda; Paris P Tekkis
Journal:  Int J Colorectal Dis       Date:  2011-01-29       Impact factor: 2.571

2.  Sacral nerve stimulation--hidden costs (uncovered).

Authors:  M Zeiton; Sara Faily; James Nicholson; Karen Telford; Abhiram Sharma
Journal:  Int J Colorectal Dis       Date:  2016-02-01       Impact factor: 2.571

Review 3.  Sacral neuromodulation stimulation in fecal incontinence.

Authors:  Tracy L Hull
Journal:  Int Urogynecol J       Date:  2010-12       Impact factor: 2.894

Review 4.  Sacral nerve stimulation in the elderly.

Authors:  Tomas L Griebling
Journal:  Int Urogynecol J       Date:  2010-12       Impact factor: 2.894

Review 5.  [Sacral nerve modulation in coloproctology].

Authors:  M Gelos; M Niedergethmann
Journal:  Chirurg       Date:  2018-06       Impact factor: 0.955

6.  Sacral nerve stimulation induces changes in the pelvic floor and rectum that improve continence and quality of life.

Authors:  Susanne Dorothea Otto; Stefanie Burmeister; Heinz J Buhr; Anton Kroesen
Journal:  J Gastrointest Surg       Date:  2010-04       Impact factor: 3.452

7.  Sacral nerve stimulation in the treatment of severe faecal incontinence: long-term clinical, manometric and quality of life results.

Authors:  P Moya; A Arroyo; J Lacueva; F Candela; L Soriano-Irigaray; A López; M A Gómez; I Galindo; R Calpena
Journal:  Tech Coloproctol       Date:  2013-04-27       Impact factor: 3.781

Review 8.  [The future of invasive neuromodulation: new techniques and expanded indications].

Authors:  A van Ophoven; J Pannek
Journal:  Urologe A       Date:  2012-02       Impact factor: 0.639

Review 9.  Faecal incontinence: Current knowledges and perspectives.

Authors:  Alban Benezech; Michel Bouvier; Véronique Vitton
Journal:  World J Gastrointest Pathophysiol       Date:  2016-02-15

10.  Efficacy of cyclic sacral nerve stimulation for faecal incontinence.

Authors:  S Norderval; C Behrenbruch; R Brouwer; J O Keck
Journal:  Tech Coloproctol       Date:  2013-03-23       Impact factor: 3.781

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