| Literature DB >> 30202798 |
Ankur Sharma1,2, David Sasaki2,3, Daniel W Rickey2,3,4, Ahmet Leylek1,2, Chad Harris3, Kate Johnson1,2, Jorge E Alpuche Aviles2,3,4, Boyd McCurdy2,3,4, Andy Egtberts3, Rashmi Koul1,2, Arbind Dubey1,2.
Abstract
PURPOSE: Three-dimensional printing has been implemented at our institution to create customized treatment accessories, including lead shields used during radiation therapy for facial skin cancer. To effectively use 3-dimensional printing, the topography of the patient must first be acquired. We evaluated a low-cost, structured-light, 3-dimensional, optical scanner to assess the clinical viability of this technology. METHODS AND MATERIALS: For ease of use, the scanner was mounted to a simple gantry that guided its motion and maintained an optimum distance between the scanner and the object. To characterize the spatial accuracy of the scanner, we used a geometric phantom and an anthropomorphic head phantom. The geometric phantom was machined from plastic and included hemispherical and tetrahedral protrusions that were roughly the dimensions of an average forehead and nose, respectively. Polygon meshes acquired by the optical scanner were compared with meshes generated from high-resolution computed tomography images. Most optical scans contained minor artifacts. Using an algorithm that calculated the distances between the 2 meshes, we found that most of the optical scanner measurements agreed with those from the computed tomography scanner within approximately 1 mm for the geometric phantom and approximately 2 mm for the head phantom. We used this optical scanner along with 3-dimensional printer technology to create custom lead shields for 10 patients receiving orthovoltage treatments of nonmelanoma skin cancers of the face. Patient, tumor, and treatment data were documented.Entities:
Year: 2018 PMID: 30202798 PMCID: PMC6128099 DOI: 10.1016/j.adro.2018.02.003
Source DB: PubMed Journal: Adv Radiat Oncol ISSN: 2452-1094
Figure 1(A) Optical scanner used to acquire 3-dimensional images. Structured light is projected in the infrared and detected with a camera. (B) Gantry and optical scanner. The scanner is moved by hand. The bed height can be adjusted to place the scan region at the isocenter.
Figure 2(A) Renderings of meshes from (left) computed tomography and (right) optical scans of the geometric phantom. A number of artifacts are visible in the optical scan. (B) The effect of the field-of-view setting on the root mean square differences between meshes obtained with computed tomography and the optical scanner. Results are for the geometric phantom and show that reducing the field of view generally increases the accuracy of the optical measurements.
Figure 3(A) Renderings of meshes from computed tomography (left) and optical scan (right) of a head phantom. The optical scanner produced artifacts in the region of the nose. (B) Spatial difference between the optical and computed tomography scans. (C) Cumulative frequency plot corresponding to the image shown in (B). Differences are between meshes obtained with computed tomography and the optical scanner. Most measurement points (89%) agree within 2 mm.
Figure 4(A) Spatial difference between meshes obtained with the optical scanner and computed tomography (Fig 2A). The optical scanner used a 40 cm field of view. (B) Cumulative frequency plot corresponding to the image of the geometric phantom shown in (A). The differences are between the 2 meshes obtained with computed tomography and the optical scanner. Most measurement points (93%) agree within 1 mm.
Patient, tumor, and treatment characteristics
| Patient number | Sex | Age (y) | Histology | Location | Stage | Dose (Gy) | Fractions | Energy (kV) |
|---|---|---|---|---|---|---|---|---|
| 1 | M | 76 | BCC | Nose | T1N0 | 40 | 10 | 250 |
| 2 | F | 78 | BCC | Nose | T2N0 | 40 | 10 | 250 |
| 3 | M | 77 | BCC | Nose | T1N0 | 40 | 10 | 250 |
| 4 | F | 84 | 1) BCC | 1) Nose | 1) T1N0 | 1) 40 | 1) 10 | 1) 250 |
| 2) BCC | 2) Nose | 2) T1N0 | 2) 40 | 2) 10 | 2) 250 | |||
| 5 | F | 69 | BCC | Nose | T1N0 | 40 | 10 | 250 |
| 6 | F | 78 | BCC | Nose | T1N0 | 36 | 6 | 100 |
| 7 | M | 67 | BCC | Nose | T2N0 | 30 | 5 | 180 |
| 8 | F | 85 | PNT/MCC | Nose | T1N0 | 55 | 22 | 250 |
| 9 | F | 79 | BCC | Nose | T1N0 | 40 | 10 | 250 |
| 10 | F | 62 | 1) BCC | 1) Nose | 1) T1N0 | 1) 55 | 1) 22 | 1) 250 |
| 2) BCC | 2) Lip | 2) T1N0 | 2) 55 | 2) 22 | 2) 250 |
BCC, basal cell carcinoma; F, female; M, male; PNT/MCC, primary neuroendocrine tumor/Merkel cell carcinoma.
Figure 5(A) On the left is the unaltered data obtained with the optical scanner. On the right is the final, edited data set that was used to print the 3-dimensional model. (B) The 3-dimensional printed model with a 3 mm lead shield molded to fit the complex facial contours. Also visible is the cutout area representing the clinical treatment field on the right side of the nose. (C) The final product, the lead shield sits on the volunteer patient's face, offering protection of the organs at risk from radiation damage.