Literature DB >> 30202287

Defining an Overdue Requiem for Palliative Cardiovascular Medicine.

Caldwell B Esselstyn1.   

Abstract

During the past 40 years, we have witnessed significant advances in the pharmaceutical and interventional treatment of cardiovascular disease (CVD), which have helped achieve a decrease in morbidity and mortality for this illness. Nevertheless, CVD remains the number 1 killer of women and men in Western civilizations. This fact is in stark contrast to the scenario in multiple whole food, plant-based nutrition (WFPBN) cultures, where CVD is virtually nonexistent. The utility of plant-based nutrition to halt and prevent CVD has been demonstrated epidemiologically, during wartime deprivation, in large cohort and population transitioning studies, and through prospective randomized and nonrandomized investigations. A basic scientific study confirms that omnivores have intestinal bacteria capable of converting animal food to trimethylamine oxide (TMAO), which injures blood vessels, whereas those eating plants only do not have intestinal bacteria capable of producing TMAO. Despite this overwhelming evidence for the safety, simplicity, and efficacy of plant nutrition to halt and prevent coronary artery disease, the cardiovascular medicine community has failed to embrace this option of therapy and persists in palliative treatments associated with high morbidity, mortality, and expense. It is long overdue to question why.

Entities:  

Keywords:  CAD; plant-based nutrition; prevent; reverse

Year:  2016        PMID: 30202287      PMCID: PMC6125067          DOI: 10.1177/1559827616638647

Source DB:  PubMed          Journal:  Am J Lifestyle Med        ISSN: 1559-8276


  23 in total

1.  Diet, lifestyle, and the etiology of coronary artery disease: the Cornell China study.

Authors:  T C Campbell; B Parpia; J Chen
Journal:  Am J Cardiol       Date:  1998-11-26       Impact factor: 2.778

2.  Lipid values in Kalahari bushmen.

Authors:  K Miller; A Rubenstein; P O Astrand
Journal:  Arch Intern Med       Date:  1968-05

3.  Saphenous vein autograft replacement of severe segmental coronary artery occlusion: operative technique.

Authors:  R G Favaloro
Journal:  Ann Thorac Surg       Date:  1968-04       Impact factor: 4.330

4.  Vinegar intake enhances flow-mediated vasodilatation via upregulation of endothelial nitric oxide synthase activity.

Authors:  Syoji Sakakibara; Ryuichiro Murakami; Mikio Takahashi; Takashi Fushimi; Toyoaki Murohara; Mikiya Kishi; Yoshitaka Kajimoto; Masafumi Kitakaze; Takayuki Kaga
Journal:  Biosci Biotechnol Biochem       Date:  2010-05-07       Impact factor: 2.043

5.  Intestinal microbial metabolism of phosphatidylcholine and cardiovascular risk.

Authors:  W H Wilson Tang; Zeneng Wang; Bruce S Levison; Robert A Koeth; Earl B Britt; Xiaoming Fu; Yuping Wu; Stanley L Hazen
Journal:  N Engl J Med       Date:  2013-04-25       Impact factor: 91.245

6.  Relationship between healthy diet and risk of cardiovascular disease among patients on drug therapies for secondary prevention: a prospective cohort study of 31 546 high-risk individuals from 40 countries.

Authors:  Mahshid Dehghan; Andrew Mente; Koon K Teo; Peggy Gao; Peter Sleight; Gilles Dagenais; Alvaro Avezum; Jeffrey L Probstfield; Tony Dans; Salim Yusuf
Journal:  Circulation       Date:  2012-12-04       Impact factor: 29.690

7.  A strategy to arrest and reverse coronary artery disease: a 5-year longitudinal study of a single physician's practice.

Authors:  C B Esselstyn; S G Ellis; S V Medendorp; T D Crowe
Journal:  J Fam Pract       Date:  1995-12       Impact factor: 0.493

8.  Risk of hospitalization or death from ischemic heart disease among British vegetarians and nonvegetarians: results from the EPIC-Oxford cohort study.

Authors:  Francesca L Crowe; Paul N Appleby; Ruth C Travis; Timothy J Key
Journal:  Am J Clin Nutr       Date:  2013-01-30       Impact factor: 7.045

9.  A way to reverse CAD?

Authors:  Caldwell B Esselstyn; Gina Gendy; Jonathan Doyle; Mladen Golubic; Michael F Roizen
Journal:  J Fam Pract       Date:  2014-07       Impact factor: 0.493

10.  Can lifestyle changes reverse coronary heart disease? The Lifestyle Heart Trial.

Authors:  D Ornish; S E Brown; L W Scherwitz; J H Billings; W T Armstrong; T A Ports; S M McLanahan; R L Kirkeeide; R J Brand; K L Gould
Journal:  Lancet       Date:  1990-07-21       Impact factor: 79.321

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