Literature DB >> 30197439

Canine visceral hemangiosarcoma treated with surgery alone or surgery and doxorubicin: 37 cases (2005-2014).

Karen Batschinski1, Alessandra Nobre1, Ernesto Vargas-Mendez1, Marcello V Tedardi1, Juliana Cirillo1, Greice Cestari1, Rodrigo Ubukata1, Maria Lucia Z Dagli1.   

Abstract

The purpose of this retrospective study was to determine survival times and prognostic factors of dogs with visceral hemangiosarcoma (HSA) treated with surgery alone or surgery and doxorubicin. Medical records from 2 hospitals from 2005 to 2014 were searched for dogs with histopathologically confirmed visceral HSA. Data relevant to patient demographics, tumor characteristics, and outcomes were abstracted. The most common primary organ affected was the spleen; however, primary tumor location had no influence on prognosis. Twenty-three dogs were treated with surgery alone, while 14 dogs were treated with surgery and doxorubicin. There was a significant difference in survival times between dogs treated with surgery alone and with surgery followed by doxorubicin (66 days versus 274 days). Dogs with stage I tumors (196 days) had a longer median survival time (MST) than dogs with stage II (117 days) and stage III (23 days) disease. The overall MST was 179 days with a 1-year survival rate of 29.2%.

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Year:  2018        PMID: 30197439      PMCID: PMC6091137     

Source DB:  PubMed          Journal:  Can Vet J        ISSN: 0008-5286            Impact factor:   1.008


  35 in total

1.  Survival time of dogs with splenic hemangiosarcoma treated by splenectomy with or without adjuvant chemotherapy: 208 cases (2001-2012).

Authors:  Kristin M Wendelburg; Lori Lyn Price; Kristine E Burgess; Jeremiah A Lyons; Felicia H Lew; John Berg
Journal:  J Am Vet Med Assoc       Date:  2015-08-15       Impact factor: 1.936

2.  Prospective study of thrombospondin-1 mimetic peptides, ABT-510 and ABT-898, in dogs with soft tissue sarcoma.

Authors:  A I Sahora; A W Rusk; J Henkin; E M McKeegan; Y Shi; C Khanna
Journal:  J Vet Intern Med       Date:  2012-07-21       Impact factor: 3.333

3.  Evaluation of clinical and histologic factors associated with survival time in dogs with stage II splenic hemangiosarcoma treated by splenectomy and adjuvant chemotherapy: 30 cases (2011-2014).

Authors:  Antony S Moore; Kenneth M Rassnick; Angela E Frimberger
Journal:  J Am Vet Med Assoc       Date:  2017-09-01       Impact factor: 1.936

4.  Imatinib and Dasatinib Inhibit Hemangiosarcoma and Implicate PDGFR-β and Src in Tumor Growth.

Authors:  Erin B Dickerson; Kevin Marley; Wade Edris; Jeffrey W Tyner; Vidya Schalk; Valerie Macdonald; Marc Loriaux; Brian J Druker; Stuart C Helfand
Journal:  Transl Oncol       Date:  2013-04-01       Impact factor: 4.243

5.  Prevalence of hemangiosarcoma in anemic dogs with a splenic mass and hemoperitoneum requiring a transfusion: 71 cases (2003-2005).

Authors:  Tara N Hammond; S Anna Pesillo-Crosby
Journal:  J Am Vet Med Assoc       Date:  2008-02-15       Impact factor: 1.936

6.  Epirubicin in the adjuvant treatment of splenic hemangiosarcoma in dogs: 59 cases (1997-2004).

Authors:  Stanley E Kim; Julius M Liptak; Trent T Gall; Gabrielle J Monteith; J Paul Woods
Journal:  J Am Vet Med Assoc       Date:  2007-11-15       Impact factor: 1.936

7.  A retrospective analysis of chemotherapy switch suggests improved outcome in surgically removed, biologically aggressive canine haemangiosarcoma.

Authors:  R Finotello; J Henriques; S Sabattini; D Stefanello; R Felisberto; S Pizzoni; R Ferrari; L Marconato
Journal:  Vet Comp Oncol       Date:  2016-01-21       Impact factor: 2.613

8.  The incidence of disseminated intravascular coagulation in dogs with malignant tumor.

Authors:  Haruhiko Maruyama; Teruhisa Miura; Manabu Sakai; Hiroshi Koie; Yoshiki Yamaya; Hisashi Shibuya; Tsuneo Sato; Toshihiro Watari; Akira Takeuchi; Mikihiko Tokuriki; Atsuhiko Hasegawa
Journal:  J Vet Med Sci       Date:  2004-05       Impact factor: 1.267

9.  Clinical and haematological features of haemangiosarcoma in dogs.

Authors:  C Y Ng; J N Mills
Journal:  Aust Vet J       Date:  1985-01       Impact factor: 1.281

Review 10.  Pathobiology of Hemangiosarcoma in Dogs: Research Advances and Future Perspectives.

Authors:  Jong-Hyuk Kim; Ashley J Graef; Erin B Dickerson; Jaime F Modiano
Journal:  Vet Sci       Date:  2015-11-06
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  5 in total

1.  Clinical validation of a next-generation sequencing-based multi-cancer early detection "liquid biopsy" blood test in over 1,000 dogs using an independent testing set: The CANcer Detection in Dogs (CANDiD) study.

Authors:  Andi Flory; Kristina M Kruglyak; John A Tynan; Lisa M McLennan; Jill M Rafalko; Patrick Christian Fiaux; Gilberto E Hernandez; Francesco Marass; Prachi Nakashe; Carlos A Ruiz-Perez; Donna M Fath; Thuy Jennings; Rita Motalli-Pepio; Kate Wotrang; Angela L McCleary-Wheeler; Susan Lana; Brenda Phillips; Brian K Flesner; Nicole F Leibman; Tracy LaDue; Chelsea D Tripp; Brenda L Coomber; J Paul Woods; Mairin Miller; Sean W Aiken; Amber Wolf-Ringwall; Antonella Borgatti; Kathleen Kraska; Christopher B Thomson; Alane Kosanovich Cahalane; Rebecca L Murray; William C Kisseberth; Maria A Camps-Palau; Franck Floch; Claire Beaudu-Lange; Aurélia Klajer-Peres; Olivier Keravel; Luc-André Fribourg-Blanc; Pascale Chicha Mazetier; Angelo Marco; Molly B McLeod; Erin Portillo; Terry S Clark; Scott Judd; C Kirk Feinberg; Marie Benitez; Candace Runyan; Lindsey Hackett; Scott Lafey; Danielle Richardson; Sarah Vineyard; Mary Tefend Campbell; Nilesh Dharajiya; Taylor J Jensen; Dirk van den Boom; Luis A Diaz; Daniel S Grosu; Arthur Polk; Kalle Marsal; Susan Cho Hicks; Katherine M Lytle; Lauren Holtvoigt; Jason Chibuk; Ilya Chorny; Dana W Y Tsui
Journal:  PLoS One       Date:  2022-04-26       Impact factor: 3.752

2.  Molecular prevalence of Bartonella, Babesia, and hemotropic Mycoplasma species in dogs with hemangiosarcoma from across the United States.

Authors:  Erin Lashnits; Pradeep Neupane; Julie M Bradley; Toni Richardson; Rachael Thomas; Keith E Linder; Matthew Breen; Ricardo G Maggi; Edward B Breitschwerdt
Journal:  PLoS One       Date:  2020-01-10       Impact factor: 3.240

3.  Retrospective evaluation of thrombocytopenia and tumor stage as prognostic indicators in dogs with splenic hemangiosarcoma.

Authors:  Alison R Masyr; Aaron K Rendahl; Amber L Winter; Antonella Borgatti; Jaime F Modiano
Journal:  J Am Vet Med Assoc       Date:  2021-03-15       Impact factor: 1.936

4.  Characterizing circulating nucleosomes in the plasma of dogs with hemangiosarcoma.

Authors:  Heather Wilson-Robles; Tasha Miller; Jill Jarvis; Jason Terrell; Theresa Kathleen Kelly; Thomas Bygott; Mhammed Bougoussa
Journal:  BMC Vet Res       Date:  2021-06-29       Impact factor: 2.741

5.  Evaluation of an autologous cancer vaccine for the treatment of metastatic canine hemangiosarcoma: a preliminary study.

Authors:  Michael D Lucroy; Ryan M Clauson; Mark A Suckow; Ferris El-Tayyeb; Ashley Kalinauskas
Journal:  BMC Vet Res       Date:  2020-11-18       Impact factor: 2.741

  5 in total

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