Aurélie Baldolli1,2, Nicolas Martin Silva3, Amélie Seguin4, Gwenola Maigne3, Audrey Sultan3, Samuel Deshayes3, Damien Du Cheyron4, Aurélie Joret4, Nizar Mahlaoui5,6,7, Boris Bienvenu8. 1. Department of Infectious Diseases, CHU de Caen, Avenue de la Côte de Nacre, 14000, Caen, France. aurelie.baldolli@yahoo.fr. 2. Groupe de Recherche sur l'Adaptation Microbienne (GRAM 2.0), Université Caen Normandie, 14000, Caen, France. aurelie.baldolli@yahoo.fr. 3. Department of Internal Medicine, CHU de Caen, Avenue de la Côte de Nacre, 14000, Caen, France. 4. Department of Intensive Care Unit, CHU de Caen, Avenue de la Côte de Nacre, 14000, Caen, France. 5. French National Reference Center for Primary Immune Deficiency (CEREDIH), Necker Enfants Malades University Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France. 6. Pediatric Immuno-Haematology and Rheumatology Unit, Necker Enfants Malades University Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France. 7. INSERM UMR1163, Imagine Institute, Sorbonne Paris Cité, University Paris Descartes, Paris, France. 8. Internal Medicine Department, Saint-Joseph Hospital, Boulevard de Louvain, 13008, Marseille, France.
Abstract
BACKGROUND: Primary immunodeficiency (PID) in adults is rare and mostly revealed by infections. MATERIAL AND METHODS: Adults without predisposing factors who were admitted to an intensive care unit (ICU) for infection were screened for PID. RESULTS: Six PID cases were diagnosed, mostly revealed by encapsulated bacterial infections. CONCLUSION: Investigation of PID after ICU discharge should be considered to improve early detection.
BACKGROUND:Primary immunodeficiency (PID) in adults is rare and mostly revealed by infections. MATERIAL AND METHODS: Adults without predisposing factors who were admitted to an intensive care unit (ICU) for infection were screened for PID. RESULTS: Six PID cases were diagnosed, mostly revealed by encapsulated bacterial infections. CONCLUSION: Investigation of PID after ICU discharge should be considered to improve early detection.
Entities:
Keywords:
Adult; Infection; Intensive care unit; Primary immunodeficiency; Secondary immunodeficiency
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