Literature DB >> 28379361

Specific Polysaccharide Antibody Deficiency Revealed by Severe Bacterial Infections in Adulthood: A Report on 11 Cases.

Benjamin Lopez1,2, Anne Boucher3, Mathilde Bahuaud4, Geoffrey Mortuaire5, Hugues Melliez6, David Launay2,3, Louis Terriou2, Lidwine Wemeau-Stervinou7, Benoît Wallaert7, Karine Faure8, Frédéric Wallet9, Eric Hachulla2,3, Pierre-Yves Hatron3, Sylvain Dubucquoi1,2, Frédéric Batteux4, Myriam Labalette1,2, Guillaume Lefèvre1,2,3.   

Abstract

We report on 11 cases of specific polysaccharide antibody deficiency (SPAD) revealed in adulthood by severe infections with encapsulated bacteria. Given that immunoglobulin replacement therapy can effectively prevent the recurrence of bacterial infections in this context, SPAD should be considered once other antibody deficiencies have been ruled out.
© The Author 2017. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.

Entities:  

Keywords:  Group A Streptococcus; Haemophilus influenzae type b; Streptococcus pneumonia; primary immunodeficiency; specific polysaccharide antibody deficiency

Mesh:

Substances:

Year:  2017        PMID: 28379361     DOI: 10.1093/cid/cix284

Source DB:  PubMed          Journal:  Clin Infect Dis        ISSN: 1058-4838            Impact factor:   9.079


  4 in total

1.  Interest of immunodeficiency screening in adult after admission in medical intensive care unit for severe infection, a retrospective and a prospective study: the Intensive Care Unit and Primary and Secondary Immunodeficiency (ICUSPID) study.

Authors:  Aurélie Baldolli; Nicolas Martin Silva; Amélie Seguin; Gwenola Maigne; Audrey Sultan; Samuel Deshayes; Damien Du Cheyron; Aurélie Joret; Nizar Mahlaoui; Boris Bienvenu
Journal:  Infection       Date:  2018-09-07       Impact factor: 3.553

2.  Immunogenicity and persistence of a prime-boost re-vaccination strategy for pneumococcal vaccines in patients with rheumatoid arthritis.

Authors:  Mathilde Bahuaud; Constance Beaudouin-Bazire; Marine Husson; Anna Molto; Odile Launay; Frédéric Batteux; Maxime Dougados
Journal:  Hum Vaccin Immunother       Date:  2018-04-09       Impact factor: 3.452

3.  Value of the Overall Pneumococcal Polysaccharide Response in the Diagnosis of Primary Humoral Immunodeficiencies.

Authors:  Benjamin Lopez; Mathilde Bahuaud; Claire Fieschi; Souad Mehlal; Mohamed Jeljeli; Stéphanie Rogeau; Séverine Brabant; Anne-Sophie Deleplancque; Sylvain Dubucquoi; Sandrine Poizot; Louis Terriou; David Launay; Frédéric Batteux; Myriam Labalette; Guillaume Lefèvre
Journal:  Front Immunol       Date:  2017-12-20       Impact factor: 7.561

4.  More than Meets the Eye: Bacteremic Pneumococcal Pneumonia as the Initial Presentation of Multiple Myeloma.

Authors:  Jonas Jautz; Eliska Potlukova; Franziska Zeeh; Michael Osthoff
Journal:  Am J Case Rep       Date:  2021-01-06
  4 in total

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