Whitney Bender1, Adi Hirshberg1, Lisa D Levine1. 1. Department of Obstetrics and Gynecology, Maternal and Child Health Research Center, Perelman School of Medicine at the University of Pennsylvania.
Abstract
OBJECTIVE: To examine the change in body mass index (BMI) categories between pregnancies and its effect on adverse pregnancy outcomes. STUDY DESIGN: We performed a retrospective cohort study of women with two consecutive deliveries from 2005 to 2010. Analysis was limited to women with BMI recorded at <24 weeks for both pregnancies. Standard BMI categories were used. Adverse pregnancy outcomes included preterm birth at <37 weeks, intrauterine growth restriction (IUGR), pregnancy-related hypertension, and gestational diabetes mellitus (GDM). Women with increased BMI category between pregnancies were compared with those who remained in the same BMI category. RESULTS: In total, 537 women were included, of whom 125 (23%) increased BMI category. There was no association between increase in BMI category and risk of preterm birth, IUGR, or pregnancy-related hypertension. Women who increased BMI category had an increased odds of GDM compared with women who remained in the same BMI category (6.4 vs. 2.2%; p = 0.018). The increased risk remained after controlling for age, history of GDM, and starting BMI (adjusted odds ratio: 8.2; 95% confidence interval: 2.1-32.7; p = 0.003). CONCLUSION: Almost one-quarter of women increased BMI categories between pregnancies. This modifiable risk factor has a significant impact on the risk of GDM. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.
OBJECTIVE: To examine the change in body mass index (BMI) categories between pregnancies and its effect on adverse pregnancy outcomes. STUDY DESIGN: We performed a retrospective cohort study of women with two consecutive deliveries from 2005 to 2010. Analysis was limited to women with BMI recorded at <24 weeks for both pregnancies. Standard BMI categories were used. Adverse pregnancy outcomes included preterm birth at <37 weeks, intrauterine growth restriction (IUGR), pregnancy-related hypertension, and gestational diabetes mellitus (GDM). Women with increased BMI category between pregnancies were compared with those who remained in the same BMI category. RESULTS: In total, 537 women were included, of whom 125 (23%) increased BMI category. There was no association between increase in BMI category and risk of preterm birth, IUGR, or pregnancy-related hypertension. Women who increased BMI category had an increased odds of GDM compared with women who remained in the same BMI category (6.4 vs. 2.2%; p = 0.018). The increased risk remained after controlling for age, history of GDM, and starting BMI (adjusted odds ratio: 8.2; 95% confidence interval: 2.1-32.7; p = 0.003). CONCLUSION: Almost one-quarter of women increased BMI categories between pregnancies. This modifiable risk factor has a significant impact on the risk of GDM. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.
Authors: Annick Bogaerts; Bea R H Van den Bergh; Lieveke Ameye; Ingrid Witters; Evelyne Martens; Dirk Timmerman; Roland Devlieger Journal: Obstet Gynecol Date: 2013-11 Impact factor: 7.661
Authors: Karen E Hannaford; Methodius G Tuuli; Linda Odibo; George A Macones; Anthony O Odibo Journal: Am J Perinatol Date: 2016-06-29 Impact factor: 1.862
Authors: Judith U Hibbard; Sharon Gilbert; Mark B Landon; John C Hauth; Kenneth J Leveno; Catherine Y Spong; Michael W Varner; Steve N Caritis; Margaret Harper; Ronald J Wapner; Yoram Sorokin; Menachem Miodovnik; Marshall Carpenter; Alan M Peaceman; Mary J O'Sullivan; Baha M Sibai; Oded Langer; John M Thorp; Susan M Ramin; Brian M Mercer; Steven G Gabbe Journal: Obstet Gynecol Date: 2006-07 Impact factor: 7.661
Authors: Anne M Lynch; Jan E Hart; Ogechi C Agwu; Barbra M Fisher; Nancy A West; Ronald S Gibbs Journal: Am J Obstet Gynecol Date: 2013-12-07 Impact factor: 8.661
Authors: Israel Hendler; Robert L Goldenberg; Brian M Mercer; Jay D Iams; Paul J Meis; Atef H Moawad; Cora A MacPherson; Steve N Caritis; Menachem Miodovnik; Kate M Menard; Gary R Thurnau; Yoram Sorokin Journal: Am J Obstet Gynecol Date: 2005-03 Impact factor: 8.661
Authors: Lisa D Levine; Hillary R Bogner; Adi Hirshberg; Michal A Elovitz; Mary D Sammel; Sindhu K Srinivas Journal: Am J Obstet Gynecol Date: 2013-10-30 Impact factor: 8.661
Authors: Catherine R Knight-Agarwal; Lauren T Williams; Deborah Davis; Rachel Davey; Tom Cochrane; Huanhua Zhang; Peter Rickwood Journal: BMJ Open Date: 2016-05-10 Impact factor: 2.692
Authors: Julie M Petersen; Mahsa M Yazdy; Kelly D Getz; Marlene T Anderka; Martha M Werler Journal: Am J Clin Nutr Date: 2021-06-01 Impact factor: 7.045
Authors: Yvon E G Timmermans; Kim D G van de Kant; Elise O Oosterman; Marc E A Spaanderman; Eduardo Villamor-Martinez; Jos Kleijnen; Anita C E Vreugdenhil Journal: Obes Rev Date: 2019-11-21 Impact factor: 9.213
Authors: Noor E W D Teulings; Katya L Masconi; Susan E Ozanne; Catherine E Aiken; Angela M Wood Journal: BMC Pregnancy Childbirth Date: 2019-10-28 Impact factor: 3.007