| Literature DB >> 30191735 |
Iftikhar Ahmed1, Zafar Niaz2, Frederick Ewbank3, Danyal Akarca3, Richard Felwick4, Manuele Furnari5.
Abstract
Distinct changes can be observed in the odor of human excretions during health and disease. Identifying underlying volatile metabolites responsible for these odorous changes can be correlated with the pathological process within the body. Advances in the technology have enabled us to interpret the volatile signature of these changes in the odor. This has opened a promising area to lay the foundations of a rapid, noninvasive and point of care diagnostic tool. This review explores the diagnostic potential of volatile organic metabolites as novel biomarkers and extends the discussion on the clinical applications of these biomarkers in gastrointestinal disorders.Entities:
Keywords: colorectal cancer; gas chromatography-mass spectrometer; gastrointestinal disorders; inflammatory bowel disease; irritable bowel syndrome; metabolomics; noninvasive biomarkers; volatile organic metabolites
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Year: 2018 PMID： 30191735 DOI： 10.2217/bmm-2018-0074
Source DB: PubMed Journal: Biomark Med ISSN： 1752-0363 Impact factor: 2.851