Literature DB >> 30184104

Antiretroviral Concentrations in Hair Strongly Predict Virologic Response in a Large Human Immunodeficiency Virus Treatment-naive Clinical Trial.

Monica Gandhi1, Peter Bacchetti2, Igho Ofokotun3, Chengshi Jin2, Heather J Ribaudo4, David W Haas5,6, Anandi N Sheth3, Howard Horng1, Nhi Phung1, Karen Kuncze1, Hideaki Okochi7, Raphael J Landovitz8, Jeffrey Lennox3, Judith S Currier8.   

Abstract

Concentrations of antiretrovirals in hair are associated with virologic outcomes in cohorts of human immunodeficiency virus (HIV)-positive individuals but have never been examined in a clinical trial. We show for the first time the predictive utility of hair antiretroviral concentrations in a large HIV treatment-naive trial (AIDS Clinical Trials Group protocol A5257).
© The Author(s) 2018. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.

Entities:  

Keywords:  A5257 study; AIDS Clinical Trials Group (ACTG); HIV; hair concentrations; non-NNRTI regimens

Mesh：

Substances：

Year:  2019        PMID： 30184104      PMCID： PMC6399433          DOI： 10.1093/cid/ciy764

Source DB:  PubMed          Journal:  Clin Infect Dis        ISSN： 1058-4838            Impact factor:   9.079


  12 in total

1.  Development and validation of an assay to analyze atazanavir in human hair via liquid chromatography/tandem mass spectrometry.

Authors:  Nhi Phung; Karen Kuncze; Hideaki Okochi; Alexander Louie; Leslie Z Benet; Igho Ofokotun; David W Haas; Judith S Currier; Tariro D Chawana; Anandi N Sheth; Peter Bacchetti; Monica Gandhi; Howard Horng
Journal:  Rapid Commun Mass Spectrom       Date:  2018-03-15       Impact factor: 2.419

2.  Behavioral intervention improves treatment outcomes among HIV-infected individuals who have delayed, declined, or discontinued antiretroviral therapy: a randomized controlled trial of a novel intervention.

Authors:  Marya Gwadz; Charles M Cleland; Elizabeth Applegate; Mindy Belkin; Monica Gandhi; Nadim Salomon; Angela Banfield; Noelle Leonard; Marion Riedel; Hannah Wolfe; Isaiah Pickens; Kelly Bolger; DeShannon Bowens; David Perlman; Donna Mildvan
Journal:  AIDS Behav       Date:  2015-10

3.  Short communication: A low-cost method for analyzing nevirapine levels in hair as a marker of adherence in resource-limited settings.

Authors:  Monica Gandhi; Qiyun Yang; Peter Bacchetti; Yong Huang
Journal:  AIDS Res Hum Retroviruses       Date:  2013-11-22       Impact factor: 2.205

Review 4.  Pre-exposure prophylaxis for HIV infection: how antiretroviral pharmacology helps to monitor and improve adherence.

Authors:  Jill Blumenthal; Richard Haubrich
Journal:  Expert Opin Pharmacother       Date:  2013-06-26       Impact factor: 3.889

5.  Brief Report: Lopinavir Hair Concentrations Are the Strongest Predictor of Viremia in HIV-Infected Asian Children and Adolescents on Second-Line Antiretroviral Therapy.

Authors:  Jillian Pintye; Peter Bacchetti; Sirinya Teeraananchai; Stephen Kerr; Wasana Prasitsuebsai; Thida Singtoroj; Karen Kuncze; Alexander Louie; Catherine A Koss; Chengshi Jin; Nhi Phung; Howard Horng; Annette H Sohn; Monica Gandhi
Journal:  J Acquir Immune Defic Syndr       Date:  2017-12-01       Impact factor: 3.731

6.  Marked intraindividual variability in antiretroviral concentrations may limit the utility of therapeutic drug monitoring.

Authors:  Richard E Nettles; Tara L Kieffer; Teresa Parsons; James Johnson; Joseph Cofrancesco; Joel E Gallant; Kathryn A Carson; Robert F Siliciano; Charles Flexner
Journal:  Clin Infect Dis       Date:  2006-03-07       Impact factor: 9.079

7.  Atazanavir concentration in hair is the strongest predictor of outcomes on antiretroviral therapy.

Authors:  Monica Gandhi; Niloufar Ameli; Peter Bacchetti; Kathryn Anastos; Stephen J Gange; Howard Minkoff; Mary Young; Joel Milam; Mardge H Cohen; Gerald B Sharp; Yong Huang; Ruth M Greenblatt
Journal:  Clin Infect Dis       Date:  2011-05       Impact factor: 9.079

8.  Efficacy and tolerability of 3 nonnucleoside reverse transcriptase inhibitor-sparing antiretroviral regimens for treatment-naive volunteers infected with HIV-1: a randomized, controlled equivalence trial.

Authors:  Jeffrey L Lennox; Raphael J Landovitz; Heather J Ribaudo; Ighovwerha Ofotokun; Lumine H Na; Catherine Godfrey; Daniel R Kuritzkes; Manish Sagar; Todd T Brown; Susan E Cohn; Grace A McComsey; Francesca Aweeka; Carl J Fichtenbaum; Rachel M Presti; Susan L Koletar; David W Haas; Kristine B Patterson; Constance A Benson; Bryan P Baugh; Randi Y Leavitt; James F Rooney; Daniel Seekins; Judith S Currier
Journal:  Ann Intern Med       Date:  2014-10-07       Impact factor: 25.391

9.  Antiretroviral concentrations in small hair samples as a feasible marker of adherence in rural Kenya.

Authors:  Matthew D Hickey; Charles R Salmen; Robert A Tessler; Dan Omollo; Peter Bacchetti; Richard Magerenge; Brian Mattah; Marcus R Salmen; Daniel Zoughbie; Kathryn J Fiorella; Elvin Geng; Betty Njoroge; Chengshi Jin; Yong Huang; Elizabeth A Bukusi; Craig R Cohen; Monica Gandhi
Journal:  J Acquir Immune Defic Syndr       Date:  2014-07-01       Impact factor: 3.731

10.  Comparison of Measures of Adherence to Human Immunodeficiency Virus Preexposure Prophylaxis Among Adolescent and Young Men Who Have Sex With Men in the United States.

Authors:  Catherine A Koss; Sybil G Hosek; Peter Bacchetti; Peter L Anderson; Albert Y Liu; Howard Horng; Leslie Z Benet; Karen Kuncze; Alexander Louie; Parya Saberi; Craig M Wilson; Monica Gandhi
Journal:  Clin Infect Dis       Date:  2018-01-06       Impact factor: 9.079
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  13 in total

Review 1.  Approaches to Objectively Measure Antiretroviral Medication Adherence and Drive Adherence Interventions.

Authors:  Matthew A Spinelli; Jessica E Haberer; Peter R Chai; Jose Castillo-Mancilla; Peter L Anderson; Monica Gandhi
Journal:  Curr HIV/AIDS Rep       Date:  2020-08       Impact factor: 5.071

2.  Tenofovir concentrations in hair strongly predict virologic suppression in breastfeeding women.

Authors:  Pamela M Murnane; Peter Bacchetti; Judith S Currier; Sean Brummel; Hideaki Okochi; Nhi Phung; Alexander Louie; Karen Kuncze; Risa M Hoffman; Teacler Nematadzira; Dean K Soko; Maxensia Owor; Friday Saidi; Patricia M Flynn; Mary G Fowler; Monica Gandhi
Journal:  AIDS       Date:  2019-08-01       Impact factor: 4.177

3.  Antiretroviral Concentration in Hair as a Measure for Antiretroviral Medication Adherence: A Systematic Review of Global Literature.

Authors:  Quan Zhang; Shan Qiao; Xueying Yang; Xiaoming Li
Journal:  AIDS Behav       Date:  2020-01

4.  Measuring Adherence to Antiretroviral Therapy via Hair Concentrations in India.

Authors:  Monica Gandhi; Sarita Devi; Peter Bacchetti; Sara Chandy; Elsa Heylen; Nhi Phung; Karen Kuncze; Hideaki Okochi; Ravi Kumar; Anura V Kurpad; Maria L Ekstrand
Journal:  J Acquir Immune Defic Syndr       Date:  2019-06-01       Impact factor: 3.731

5.  Development and validation of a liquid chromatography-tandem mass spectrometry method for quantifying delamanid and its metabolite in small hair samples.

Authors:  Andrew Reckers; Stella Huo; Ali Esmail; Keertan Dheda; Peter Bacchetti; Monica Gandhi; John Metcalfe; Roy Gerona
Journal:  J Chromatogr B Analyt Technol Biomed Life Sci       Date:  2020-12-10       Impact factor: 3.205

6.  Effect of Text Messaging Plus Peer Navigation on Viral Suppression Among Youth With HIV in the iCARE Nigeria Pilot Study.

Authors:  Babafemi O Taiwo; Kehinde M Kuti; Lisa M Kuhns; Olayinka Omigbodun; Olutosin Awolude; Adedotun Adetunji; Baiba Berzins; Patrick Janulis; Amy K Johnson; Ogochukwu Okonkwor; Bibilola D Oladeji; Abigail Muldoon; Olubusuyi M Adewumi; Paul Amoo; Hannah Atunde; Bill Kapogiannis; Robert Garofalo
Journal:  J Acquir Immune Defic Syndr       Date:  2021-08-01       Impact factor: 3.771

7.  Antiretroviral hair levels, self-reported adherence, and virologic failure in second-line regimen patients in resource-limited settings.

Authors:  Tanakorn Apornpong; Beatriz Grinsztejn; Michael Hughes; Justin Ritz; Stephen J Kerr; Courtney V Fletcher; Kiat Ruxrungtham; Catherine Godfrey; Robert Gross; Evelyn Hogg; Carole L Wallis; Sharlaa Badal-Faesen; Mina C Hosseinipour; Rosie Mngqbisa; Breno R Santos; Sarita Shah; Laura J Hovind; Sajeeda Mawlana; Marije Van Schalkwyk; Nuntisa Chotirosniramit; Cecilia Kanyama; Nagalingeswaran Kumarasamy; Robert Salata; Ann C Collier; Monica Gandhi
Journal:  AIDS       Date:  2021-07-15       Impact factor: 4.632

8.  Tenofovir and emtricitabine concentrations in hair are comparable between individuals on tenofovir disoproxil fumarate versus tenofovir alafenamide-based ART.

Authors:  Hideaki Okochi; Alexander Louie; Nhi Phung; Kevin Zhang; Regina M Tallerico; Karen Kuncze; Matthew A Spinelli; Catherine A Koss; Leslie Z Benet; Monica Gandhi
Journal:  Drug Test Anal       Date:  2021-04-13       Impact factor: 3.234

Review 9.  Sample preparation techniques for extraction of vitamin D metabolites from non-conventional biological sample matrices prior to LC-MS/MS analysis.

Authors:  Anastasia Alexandridou; Dietrich A Volmer
Journal:  Anal Bioanal Chem       Date:  2022-05-02       Impact factor: 4.478

10.  Association of anti-tuberculosis drug concentrations in hair and treatment outcomes in MDR- and XDR-TB.

Authors:  John Metcalfe; Peter Bacchetti; Roy Gerona; Ali Esmail; Keertan Dheda; Monica Gandhi
Journal:  ERJ Open Res       Date:  2019-04-26
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