Literature DB >> 30177818

Turning cold tumours hot: oncolytic virotherapy gets up close and personal with other therapeutics at the 11th Oncolytic Virus Conference.

Arthur Dyer1, Richard Baugh1, Suet Lin Chia2, Sally Frost1, Egon J Jacobus1, Hena Khalique1, Tzveta D Pokrovska1, Eleanor M Scott1, William K Taverner1, Len W Seymour3, Janet Lei4.   

Abstract

The 11th International Oncolytic Virus Conference (IOVC) was held from April 9-12, 2018 in Oxford, UK. This is part of the high-profile academic-led series of meetings that was started back in 2002 by Steve Russell and John Bell, with most of the previous meetings being held in North America (often in Banff). The conference brought together many of the major players in oncolytic virotherapy from all over the world, addressing all stages of research and development-from aspects of basic science and cellular immunology all the way through to early- and late-phase clinical trials. The meeting welcomed 352 delegates from 24 countries. The top seven delegate countries, namely, the UK, US, Canada, The Netherlands, Germany, Japan and South Korea, contributed 291 delegates while smaller numbers coming from Australia, Austria, Bulgaria, China, Finland, France, Iraq, Ireland, Israel, Italy, Latvia, Malaysia, Poland, Slovenia, Spain, Sweden and Switzerland. Academics comprised about half of the attendees, industry 30% and students 20%. The next IOVC is scheduled to be held on Vancouver Island in autumn 2019. Here we share brief summaries of the oral presentations from invited speakers and proffered papers in the different subtopics presented at IOVC 2018.

Entities:  

Year:  2018        PMID: 30177818     DOI: 10.1038/s41417-018-0042-1

Source DB:  PubMed          Journal:  Cancer Gene Ther        ISSN: 0929-1903            Impact factor:   5.987


  8 in total

1.  Oncolytic Activity of Targeted Picornaviruses Formulated as Synthetic Infectious RNA.

Authors:  Noura B Elsedawy; Rebecca A Nace; Stephen J Russell; Autumn J Schulze
Journal:  Mol Ther Oncolytics       Date:  2020-05-19       Impact factor: 7.200

Review 2.  Oncolytic Measles Virotherapy and Opposition to Measles Vaccination.

Authors:  Stephen J Russell; Dusica Babovic-Vuksanovic; Alice Bexon; Roberto Cattaneo; David Dingli; Angela Dispenzieri; David R Deyle; Mark J Federspiel; Adele Fielding; Eva Galanis; Martha Q Lacy; Bradley C Leibovich; Minetta C Liu; Miguel Muñoz-Alía; Tanner C Miest; Julian R Molina; Sabine Mueller; Scott H Okuno; Nandakumar Packiriswamy; Tobias Peikert; Corey Raffel; Frits Van Rhee; Guy Ungerechts; Paul R Young; Yumei Zhou; Kah-Whye Peng
Journal:  Mayo Clin Proc       Date:  2019-06-22       Impact factor: 7.616

3.  Recombinant Adenovirus Expressing a Soluble Fusion Protein PD-1/CD137L Subverts the Suppression of CD8+ T Cells in HCC.

Authors:  Yonghui Zhang; Hailin Zhang; Mei Wei; Tao Mou; Tao Shi; Yanyu Ma; Xinyu Cai; Yunzheng Li; Jie Dong; Jiwu Wei
Journal:  Mol Ther       Date:  2019-08-05       Impact factor: 11.454

4.  First-in-human study of TK-positive oncolytic vaccinia virus delivered by adipose stromal vascular fraction cells.

Authors:  Boris R Minev; Elliot Lander; John F Feller; Mark Berman; Bernadette M Greenwood; Ivelina Minev; Antonio F Santidrian; Duong Nguyen; Dobrin Draganov; Mehmet O Killinc; Anna Vyalkova; Santosh Kesari; Edward McClay; Gabriel Carabulea; Francesco M Marincola; Lisa H Butterfield; Aladar A Szalay
Journal:  J Transl Med       Date:  2019-08-19       Impact factor: 8.440

Review 5.  Insights Into Lung Cancer Immune-Based Biology, Prevention, and Treatment.

Authors:  Sara Saab; Hussein Zalzale; Zahraa Rahal; Yara Khalifeh; Ansam Sinjab; Humam Kadara
Journal:  Front Immunol       Date:  2020-02-11       Impact factor: 7.561

6.  Oncolytic viral immunotherapy in the time of COVID-19.

Authors:  David Olagnier; Tommy Alain
Journal:  Cytokine Growth Factor Rev       Date:  2020-11-04       Impact factor: 7.638

7.  Calcium Influx Caused by ER Stress Inducers Enhances Oncolytic Adenovirus Enadenotucirev Replication and Killing through PKCα Activation.

Authors:  William K Taverner; Egon J Jacobus; John Christianson; Brian Champion; Adrienne W Paton; James C Paton; Weiheng Su; Ryan Cawood; Len W Seymour; Janet Lei-Rossmann
Journal:  Mol Ther Oncolytics       Date:  2019-09-28       Impact factor: 7.200

Review 8.  Combinatorial Approaches for Cancer Treatment Using Oncolytic Viruses: Projecting the Perspectives through Clinical Trials Outcomes.

Authors:  Alexander Malogolovkin; Nizami Gasanov; Alexander Egorov; Marianna Weener; Roman Ivanov; Alexander Karabelsky
Journal:  Viruses       Date:  2021-06-29       Impact factor: 5.048

  8 in total

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