| Literature DB >> 31235278 |
Stephen J Russell1, Dusica Babovic-Vuksanovic2, Alice Bexon3, Roberto Cattaneo4, David Dingli5, Angela Dispenzieri6, David R Deyle2, Mark J Federspiel4, Adele Fielding7, Eva Galanis8, Martha Q Lacy6, Bradley C Leibovich9, Minetta C Liu10, Miguel Muñoz-Alía4, Tanner C Miest9, Julian R Molina10, Sabine Mueller11, Scott H Okuno10, Nandakumar Packiriswamy4, Tobias Peikert12, Corey Raffel11, Frits Van Rhee13, Guy Ungerechts14, Paul R Young15, Yumei Zhou4, Kah-Whye Peng4.
Abstract
Recent measles epidemics in US and European cities where vaccination coverage has declined are providing a harsh reminder for the need to maintain protective levels of immunity across the entire population. Vaccine uptake rates have been declining in large part because of public misinformation regarding a possible association between measles vaccination and autism for which there is no scientific basis. The purpose of this article is to address a new misinformed antivaccination argument-that measles immunity is undesirable because measles virus is protective against cancer. Having worked for many years to develop engineered measles viruses as anticancer therapies, we have concluded (1) that measles is not protective against cancer and (2) that its potential utility as a cancer therapy will be enhanced, not diminished, by prior vaccination.Entities:
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Year: 2019 PMID： 31235278 PMCID： PMC6800178 DOI： 10.1016/j.mayocp.2019.05.006
Source DB: PubMed Journal: Mayo Clin Proc ISSN： 0025-6196 Impact factor: 7.616