Literature DB >> 3017764

Complete amino acid sequence of the large subunit of the low-Ca2+-requiring form of human Ca2+-activated neutral protease (muCANP) deduced from its cDNA sequence.

K Aoki, S Imajoh, S Ohno, Y Emori, M Koike, G Kosaki, K Suzuki.   

Abstract

The complete amino acid sequence of the large subunit (catalytic subunit) of human low-Ca2+-requiring-calcium-activated neutral protease (muCANP) was deduced from its cDNA base sequence. It is composed of 714 amino acid residues and its sequence is highly homologous to the chicken CANP sequence determined previously. Human muCANP, like chicken CANP, has a clear 4-domain structure, and their fundamental structures are essentially the same, although their Ca2+ sensitivities are significantly different. The role of each domain in the Ca2+ sensitivity and protease activity of CANP is discussed on the basis of sequence comparison.

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Year:  1986        PMID: 3017764     DOI: 10.1016/0014-5793(86)80919-x

Source DB:  PubMed          Journal:  FEBS Lett        ISSN: 0014-5793            Impact factor:   4.124


  21 in total

1.  Regulation of calpain and calpastatin in differentiating myoblasts: mRNA levels, protein synthesis and stability.

Authors:  S Barnoy; L Supino-Rosin; N S Kosower
Journal:  Biochem J       Date:  2000-10-15       Impact factor: 3.857

2.  Protective effects of calpain inhibitor for prolonged hypothermic cardiac preservation.

Authors:  T Saito; A Mishima; M Asano; T Ukai; S Yamamoto; M Kunimatsu; M Sasaki; T Manabe
Journal:  Jpn J Thorac Cardiovasc Surg       Date:  1999-04

3.  Evolution of EF-hand calcium-modulated proteins. I. Relationships based on amino acid sequences.

Authors:  N D Moncrief; R H Kretsinger; M Goodman
Journal:  J Mol Evol       Date:  1990-06       Impact factor: 2.395

4.  An alpha-mercaptoacrylic acid derivative is a selective nonpeptide cell-permeable calpain inhibitor and is neuroprotective.

Authors:  K K Wang; R Nath; A Posner; K J Raser; M Buroker-Kilgore; I Hajimohammadreza; W Probert A; F W Marcoux; Q Ye; E Takano; M Hatanaka; M Maki; H Caner; J L Collins; A Fergus; K S Lee; E A Lunney; S J Hays; P Yuen
Journal:  Proc Natl Acad Sci U S A       Date:  1996-06-25       Impact factor: 11.205

5.  Chromosomal localization of the porcine skeletal muscle calpain gene.

Authors:  G P Briley; P K Riggs; J E Womack; D L Hancock; C A Bidwell
Journal:  Mamm Genome       Date:  1996-03       Impact factor: 2.957

6.  Biologically active monomeric and heterodimeric recombinant human calpain I produced using the baculovirus expression system.

Authors:  S L Meyer; D Bozyczko-Coyne; S K Mallya; C M Spais; R Bihovsky; J K Kaywooya; D M Lang; R W Scott; R Siman
Journal:  Biochem J       Date:  1996-03-01       Impact factor: 3.857

7.  Mapping, cloning, cDNA sequence, and expression of the gene encoding the mouse micromolar calpain large subunit.

Authors:  C Poirier; S Poussard; D M Faust; T Imaizumi-Scherrer; M C Weiss; A Ducastaing; D Montarras; C Pinset; J L Guénet
Journal:  Mamm Genome       Date:  1998-05       Impact factor: 2.957

Review 8.  Calmodulin-binding proteins as calpain substrates.

Authors:  K K Wang; A Villalobo; B D Roufogalis
Journal:  Biochem J       Date:  1989-09-15       Impact factor: 3.857

9.  A region of basic amino-acid cluster in HIV-1 Tat protein is essential for trans-acting activity and nucleolar localization.

Authors:  S Endo; S Kubota; H Siomi; A Adachi; S Oroszlan; M Maki; M Hatanaka
Journal:  Virus Genes       Date:  1989-11       Impact factor: 2.332

10.  Genetic mapping studies of 40 loci and 23 cosmids in chromosome 11p13-11q13, and exclusion of mu-calpain as the multiple endocrine neoplasia type 1 gene.

Authors:  J T Pang; S E Lloyd; C Wooding; B Farren; B Pottinger; B Harding; S E Leigh; M A Pook; F J Benham; G T Gillett; R T Taggart; R V Thakker
Journal:  Hum Genet       Date:  1996-06       Impact factor: 4.132

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