| Literature DB >> 30176659 |
Oliviero Quercia1, Vittoria Cova2, Matteo Martini3, Gabriele Cortellini4, Francesco Murzilli5, Donatella Bignardi6, Marcello Cilia7, Alessandro Scarpa8, Maria Beatrice Bilò9.
Abstract
Cross-reactions between Polistes dominula and Vespula species are common in southern Europe. Currently, only CAP-inhibition demonstrates high accuracy in identifying genuine sensitizations, but this method is time-consuming and expensive, so a new approach is required. This study investigates skin tests, molecular diagnostics, total IgE (tIgE), and the Ves v 5/Pol d 5 (or vice versa) ratio. The ratio generated low-accuracy results and poor agreement with CAP-inhibition, and we did not find any agreement between CAP-inhibition test and double values of Ves v 5/Pol d 5. Nevertheless, a slight diagnostic improvement was obtained when Ves v 5/tIgE and Pol d 5/tIgE were measured.Entities:
Keywords: Allergy; CAP-inhibition; Cross-reactivity; Polistes; Vespula
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Year: 2018 PMID: 30176659 DOI: 10.1159/000491939
Source DB: PubMed Journal: Int Arch Allergy Immunol ISSN: 1018-2438 Impact factor: 2.749