Literature DB >> 30174567

Delayed and fractional use of enzymatic debridement with nexobrid for extensive burn injury: a case report.

S Krauss1, D Bender1, J Rothenberger1, J Daigeler1, M Held1.   

Abstract

Selective enzymatic debridement is increasingly being used in cases of burn wounds. However, until now the use of Nexobrid has been limited to 15% of total body surface area (TBSA) and immediate use on admission day. A 61-year-old Caucasian male suffered a severe burn injury that affected 95% TBSA. After surgical escharotomy and tracheotomy on admission day, we successfully performed a fractional enzymatic debridement of 54% of the TBSA in three different sessions within four days. This case report reveals that a delayed and fractional application of Nexobrid to more than 15% TBSA is possible.

Entities:  

Keywords:  Nexobrid; case report; enzymatic debridement; extensive burn injury

Year:  2018        PMID： 30174567      PMCID： PMC6116646     

Source DB:  PubMed          Journal:  Ann Burns Fire Disasters        ISSN： 1592-9558


  9 in total

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Journal:  J Trauma       Date:  2000-12

Review 2.  Excision and skin grafting of thermal burns.

Authors:  Dennis P Orgill
Journal:  N Engl J Med       Date:  2009-02-26       Impact factor: 91.245

Review 3.  Meta-analysis of early excision of burns.

Authors:  Yee Siang Ong; Miny Samuel; Colin Song
Journal:  Burns       Date:  2006-01-18       Impact factor: 2.744

4.  Minimally invasive burn care: a review of seven clinical studies of rapid and selective debridement using a bromelain-based debriding enzyme (Nexobrid®).

Authors:  L Rosenberg; Y Shoham; Y Krieger; G Rubin; F Sander; J Koller; K David; D Egosi; R Ahuja; A J Singer
Journal:  Ann Burns Fire Disasters       Date:  2015-12-31

5.  Escharotomy using an enzymatic debridement agent for treating experimental burn-induced compartment syndrome in an animal model.

Authors:  Yuval Krieger; Lior Rosenberg; Oren Lapid; Ronen Glesinger; Alex Bogdanov-Berezovsky; Eldad Silberstein; Amiram Sagi; Keith Judkins
Journal:  J Trauma       Date:  2005-06

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Journal:  J Trauma       Date:  1974-05

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Authors:  Z Janzekovic
Journal:  J Trauma       Date:  1970-12

8.  A novel rapid and selective enzymatic debridement agent for burn wound management: a multi-center RCT.

Authors:  Lior Rosenberg; Yuval Krieger; Alex Bogdanov-Berezovski; Eldad Silberstein; Yaron Shoham; Adam J Singer
Journal:  Burns       Date:  2013-09-26       Impact factor: 2.744

Review 9.  Growth factor-regulated pathways in epithelial cell proliferation.

Authors:  S A Aaronson; J S Rubin; P W Finch; J Wong; C Marchese; J Falco; W G Taylor; M H Kraus
Journal:  Am Rev Respir Dis       Date:  1990-12
  9 in total
  1 in total

1.  A Questionnaire-Based Study to Obtain a Consensus from 5 Polish Burns Centers on Eschar Removal by Bromelain-Based Enzymatic Debridement (Nexobrid®) in Burns Following the 2020 Updated European Consensus Guidelines.

Authors:  Tomasz Korzeniowski; Jerzy Strużyna; Anna M Chrapusta; Andrzej Krajewski; Marek Kucharzewski; Krzysztof Piorun; Jakub Nowakowski; Agnieszka Surowiecka; Magdalena Kozicka; Kamil Torres
Journal:  Med Sci Monit       Date:  2022-01-22
  1 in total

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