Ho-Joong Kim1, Saejong Park2, Soo-Hyun Park2, Jeong Hyun Lee1, Bong-Soon Chang3, Choon-Ki Lee3, Jin S Yeom4. 1. Spine Center and Department of Orthopedic Surgery, Seoul National University College of Medicine and Seoul National University Bundang Hospital, 166 Gumiro, Bundang-gu, Sungnam, 463-707, Republic of Korea. 2. Division of Sports Science, Korea Institute of Sports Science, 727 Hwarang-lo Nowon-gu, Seoul, 139-242, Republic of Korea. 3. Department of Orthopaedic Surgery, Seoul National University College of Medicine and Seoul National University Hospital, 101 Daehangno, Jongno-gu, Seoul, 110-744, Republic of Korea. 4. Spine Center and Department of Orthopedic Surgery, Seoul National University College of Medicine and Seoul National University Bundang Hospital, 166 Gumiro, Bundang-gu, Sungnam, 463-707, Republic of Korea. highcervical@gmail.com.
Abstract
PURPOSE: To investigate the prevalence of frailty in patients with symptomatic lumbar spinal stenosis (LSS) and a propensity score-matched control group, and to analyze the association between symptomatic LSS and frailty. METHODS: This study included 2 groups: 1 consisting of patients with symptomatic LSS (LSS group) and the other including healthy elderly subjects without degenerative spinal disease (control group). Baseline sociodemographic data, variables regarding frailty assessment, and clinical outcomes were collected. The frailty was assessed with Fried criteria. Between the LSS and control groups, the prevalence of frailty was compared. Among all participants, risk factors for frailty were identified using multivariate logistic regression. RESULTS: Totally, 843 subjects participated (142 in LSS group and 701 in control group) in this study. After the propensity score matching (142 in each group), the LSS group had significantly higher prevalence of frail than the control group (P < 0.001): 59 (41.5%) participants in the LSS group were frail, whereas 10 (7.0%) participants in the control group were frail. Within LSS group analysis showed that participants with frailty had significantly higher disability and lower quality of life compared to those in a robust state. Among all participants, LSS and age were found to be significant risk factors for frail in multivariate logistic regression model. CONCLUSIONS: The present study highlights a strong association between symptomatic LSS and frailty. Furthermore, symptom severity and disability caused by LSS are significantly related to frailty. Therefore, early detection and appropriate treatment for frailty in patients with LSS is important. These slides can be retrieved under Electronic Supplementary Material.
PURPOSE: To investigate the prevalence of frailty in patients with symptomatic lumbar spinal stenosis (LSS) and a propensity score-matched control group, and to analyze the association between symptomatic LSS and frailty. METHODS: This study included 2 groups: 1 consisting of patients with symptomatic LSS (LSS group) and the other including healthy elderly subjects without degenerative spinal disease (control group). Baseline sociodemographic data, variables regarding frailty assessment, and clinical outcomes were collected. The frailty was assessed with Fried criteria. Between the LSS and control groups, the prevalence of frailty was compared. Among all participants, risk factors for frailty were identified using multivariate logistic regression. RESULTS: Totally, 843 subjects participated (142 in LSS group and 701 in control group) in this study. After the propensity score matching (142 in each group), the LSS group had significantly higher prevalence of frail than the control group (P < 0.001): 59 (41.5%) participants in the LSS group were frail, whereas 10 (7.0%) participants in the control group were frail. Within LSS group analysis showed that participants with frailty had significantly higher disability and lower quality of life compared to those in a robust state. Among all participants, LSS and age were found to be significant risk factors for frail in multivariate logistic regression model. CONCLUSIONS: The present study highlights a strong association between symptomatic LSS and frailty. Furthermore, symptom severity and disability caused by LSS are significantly related to frailty. Therefore, early detection and appropriate treatment for frailty in patients with LSS is important. These slides can be retrieved under Electronic Supplementary Material.
Authors: Devyani Misra; David T Felson; Rebecca A Silliman; Michael Nevitt; Cora E Lewis; James Torner; Tuhina Neogi Journal: J Gerontol A Biol Sci Med Sci Date: 2014-07-25 Impact factor: 6.053
Authors: Sharon K Inouye; Edward R Marcantonio; Zara Cooper; Selwyn O Rogers; Long Ngo; Jamey Guess; Eva Schmitt; Richard N Jones; Douglas K Ayres; Jeremy D Walston; Thomas M Gill; Lauren J Gleason Journal: J Am Geriatr Soc Date: 2016-11-01 Impact factor: 5.562
Authors: Sarah E Tom; Jonathan D Adachi; Frederick A Anderson; Steven Boonen; Roland D Chapurlat; Juliet E Compston; Cyrus Cooper; Stephen H Gehlbach; Susan L Greenspan; Frederick H Hooven; Jeri W Nieves; Johannes Pfeilschifter; Christian Roux; Stuart Silverman; Allison Wyman; Andrea Z LaCroix Journal: J Am Geriatr Soc Date: 2013-01-25 Impact factor: 5.562