Literature DB >> 3016920

Localization of multidrug resistance-associated DNA sequences to human chromosome 7.

A Fojo, R Lebo, N Shimizu, J E Chin, I B Roninson, G T Merlino, M M Gottesman, I Pastan.   

Abstract

Multidrug resistance in several human cell lines correlates with amplification or increased expression of two related DNA sequences, designated mdr1 and mdr2. These DNA sequences were used as probes for hybridization with DNA with a panel of human-mouse somatic cell hybrids and from individual human chromosomes separated by fluorescence-activated chromosome sorting. By these assays, both mdr1 and mdr2 sequences were localized to chromosome 7.

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Year:  1986        PMID： 3016920     DOI： 10.1007/bf01570737

Source DB:  PubMed          Journal:  Somat Cell Mol Genet        ISSN： 0740-7750


  20 in total

1.  A polymorphic HindIII site within the human multidrug resistance gene 1 (MDR1).

Authors:  K Yoshimoto; H Iwahana; Y Yokogoshi; S Saito; M Shiraishi; T Sekiya; M M Gottesman; I Pastan
Journal:  Nucleic Acids Res       Date:  1988-12-23       Impact factor: 16.971

2.  MspI/HpaII polymorphism in the human multidrug resistance gene 1.

Authors:  D A Haber; D E Housman
Journal:  Nucleic Acids Res       Date:  1989-12-11       Impact factor: 16.971

3.  Localization of the human multiple drug resistance gene, MDR1, to 7q21.1.

Authors:  D F Callen; E Baker; R N Simmers; R Seshadri; I B Roninson
Journal:  Hum Genet       Date:  1987-10       Impact factor: 4.132

Review 4.  Genetic markers on chromosome 7.

Authors:  L C Tsui
Journal:  J Med Genet       Date:  1988-05       Impact factor: 6.318

5.  RFLPs associated with MDR2, a member of the human multidrug resistance gene family mapped to chromosome 7.

Authors:  K Choi; L E Hake; A M Bowcock; I B Roninson; L L Cavalli-Sforza
Journal:  Nucleic Acids Res       Date:  1987-08-11       Impact factor: 16.971

6.  Multidrug resistance of DNA-mediated transformants is linked to transfer of the human mdr1 gene.

Authors:  D W Shen; A Fojo; I B Roninson; J E Chin; R Soffir; I Pastan; M M Gottesman
Journal:  Mol Cell Biol       Date:  1986-11       Impact factor: 4.272

Review 7.  A synonymous polymorphism in a common MDR1 (ABCB1) haplotype shapes protein function.

Authors:  King Leung Fung; Michael M Gottesman
Journal:  Biochim Biophys Acta       Date:  2009-03-11

Review 8.  P-glycoprotein expression and regulation. Age-related changes and potential effects on drug therapy.

Authors:  S Gupta
Journal:  Drugs Aging       Date:  1995-07       Impact factor: 3.923

Review 9.  Molecular cytogenetics of multiple drug resistance.

Authors:  P V Schoenlein
Journal:  Cytotechnology       Date:  1993       Impact factor: 2.058

10.  ABCB1 C3435T polymorphism and response to clopidogrel treatment in coronary artery disease (CAD) patients: a meta-analysis.

Authors:  Jia Su; Jin Xu; Xiaojing Li; Han Zhang; Juwei Hu; Renyuan Fang; Xiaomin Chen
Journal:  PLoS One       Date:  2012-10-09       Impact factor: 3.240
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