Literature DB >> 30168064

Correlation between Expression of KLF5 and ZEB1 Transcription Factor Genes in Pancreatic Cancer.

M V Zinovyeva1, L G Nikolaev2, L G Kondratyeva2, T V Vinogradova2, E D Sverdlov2.   

Abstract

The mRNA content of the transcription factors KLF5 and ZEB1 was studied in pancreatic tumor tissues and in fetal and normal pancreas. Transcription of these factors was not high and similar in normal and fetal pancreatic tissues but greatly increased in the pancreatic ductal adenocarcinoma tissues. A significant positive correlation between the KLF5 and ZEB1 transcription levels in the pancreatic tumor tissues was observed.

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Year:  2018        PMID： 30168064     DOI： 10.1134/S1607672918040129

Source DB:  PubMed          Journal:  Dokl Biochem Biophys        ISSN： 1607-6729            Impact factor:   0.788


  9 in total

Review 1.  Cellular and molecular mechanisms coordinating pancreas development.

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Journal:  Development       Date:  2017-08-15       Impact factor: 6.868

2.  Expression of transcription factor genes in cell lines corresponding to different stages of pancreatic cancer progression.

Authors:  I R Abjalimov; M V Zinovyeva; L G Nikolaev; M R Kopantzeva; E P Kopantzev; E D Sverdlov
Journal:  Dokl Biochem Biophys       Date:  2017-09-02       Impact factor: 0.788

Review 3.  Pleiotropic Roles for ZEB1 in Cancer.

Authors:  Julie Caramel; Maud Ligier; Alain Puisieux
Journal:  Cancer Res       Date:  2017-12-18       Impact factor: 12.701

Review 4.  Pancreas organogenesis: from lineage determination to morphogenesis.

Authors:  Hung Ping Shih; Allen Wang; Maike Sander
Journal:  Annu Rev Cell Dev Biol       Date:  2013-07-31       Impact factor: 13.827

5.  The EMT-activator Zeb1 is a key factor for cell plasticity and promotes metastasis in pancreatic cancer.

Authors:  Angela M Krebs; Julia Mitschke; María Lasierra Losada; Otto Schmalhofer; Melanie Boerries; Hauke Busch; Martin Boettcher; Dimitrios Mougiakakos; Wilfried Reichardt; Peter Bronsert; Valerie G Brunton; Christian Pilarsky; Thomas H Winkler; Simone Brabletz; Marc P Stemmler; Thomas Brabletz
Journal:  Nat Cell Biol       Date:  2017-04-17       Impact factor: 28.824

6.  Identification of some human genes oppositely regulated during esophageal squamous cell carcinoma formation and human embryonic esophagus development.

Authors:  M V Zinovyeva; G S Monastyrskaya; E P Kopantzev; T V Vinogradova; M B Kostina; A V Sass; O B Filyukova; N Y Uspenskaya; G T Sukhikh; E D Sverdlov
Journal:  Dis Esophagus       Date:  2009-08-28       Impact factor: 3.429

7.  Krüppel-like Factor 5, Increased in Pancreatic Ductal Adenocarcinoma, Promotes Proliferation, Acinar-to-Ductal Metaplasia, Pancreatic Intraepithelial Neoplasia, and Tumor Growth in Mice.

Authors:  Ping He; Jong Won Yang; Vincent W Yang; Agnieszka B Bialkowska
Journal:  Gastroenterology       Date:  2017-12-15       Impact factor: 22.682

8.  Dissection of transcriptional and cis-regulatory control of differentiation in human pancreatic cancer.

Authors:  Giuseppe R Diaferia; Chiara Balestrieri; Elena Prosperini; Paola Nicoli; Paola Spaggiari; Alessandro Zerbi; Gioacchino Natoli
Journal:  EMBO J       Date:  2016-01-14       Impact factor: 11.598

9.  Differences in gene expression levels between early and later stages of human lung development are opposite to those between normal lung tissue and non-small lung cell carcinoma.

Authors:  Eugene P Kopantzev; Galina S Monastyrskaya; Tatyana V Vinogradova; Marina V Zinovyeva; Marya B Kostina; Olga B Filyukova; Alexander G Tonevitsky; Gennady T Sukhikh; Eugene D Sverdlov
Journal:  Lung Cancer       Date:  2008-04-03       Impact factor: 5.705
  9 in total

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