Literature DB >> 30167942

Twin Inc.

Rose Hershenov1,2, Derek Doroski3.   

Abstract

This paper presents an account of how human spontaneous embryonic chimeras are formed. On the prevalent view in the philosophical literature, it is said that chimeras are the product of two embryos that fuse to form a new third embryo. We call this version of fusion synthesis. In contrast to synthesis, we present an alternative mechanism for chimera formation called incorporation, wherein one embryo incorporates the cells of a second embryo into its body. We argue that the incorporation thesis explains other types of chimera formation, which are better understood, and is more consistent than synthesis with what is known about embryological development. Incorporation also has different implications than synthesis and so avoids the philosophical puzzles that are often said to accompany embryonic chimera formation-puzzles which pose problems to the human embryo's persistence from fertilization to the fetal stage of human development.

Entities:  

Keywords:  Chimera; Fusion; Human embryo

Mesh:

Year:  2018        PMID: 30167942     DOI: 10.1007/s11017-018-9461-0

Source DB:  PubMed          Journal:  Theor Med Bioeth        ISSN: 1386-7415


  34 in total

1.  Sixteen days.

Authors:  Barry Smith; Berit Brogaard
Journal:  J Med Philos       Date:  2003-02

2.  Maternal cell microchimerism in newborn tissues.

Authors:  Bharath Srivatsa; Sumathi Srivatsa; Kirby L Johnson; Diana W Bianchi
Journal:  J Pediatr       Date:  2003-01       Impact factor: 4.406

3.  Stem cells derived from 'dead' human embryo.

Authors:  Helen Pearson; Alison Abbott
Journal:  Nature       Date:  2006-09-28       Impact factor: 49.962

4.  Substance ontology cannot determine the moral status of embryos.

Authors:  Jason Morris
Journal:  J Med Philos       Date:  2012-08-14

5.  The ontological status of embryos: a reply to Jason Morris.

Authors:  Patrick Lee; Christopher Tollefsen; Robert P George
Journal:  J Med Philos       Date:  2014-10

6.  The Constitution of the Human Embryo as Substantial Change.

Authors:  David Alvargonzález
Journal:  J Med Philos       Date:  2016-02-04

7.  Fetus in fetu: A report of two cases.

Authors:  Ibrahim Karaman; Derya Erdoğan; Semire Ozalevli; Ayşe Karaman; Y Hakan Cavuşoğlu; M Kemal Aslan; Ozden Cakmak
Journal:  J Indian Assoc Pediatr Surg       Date:  2008-01

8.  The potential of the human embryo.

Authors:  Mark T Brown
Journal:  J Med Philos       Date:  2007 Nov-Dec

Review 9.  Traces of embryogenesis are the same in monozygotic and dizygotic twins: not compatible with double ovulation.

Authors:  Charles E Boklage
Journal:  Hum Reprod       Date:  2009-02-27       Impact factor: 6.918

10.  Human stem cells from single blastomeres reveal pathways of embryonic or trophoblast fate specification.

Authors:  Tamara Zdravkovic; Kristopher L Nazor; Nicholas Larocque; Matthew Gormley; Matthew Donne; Nathan Hunkapillar; Gnanaratnam Giritharan; Harold S Bernstein; Grace Wei; Matthias Hebrok; Xianmin Zeng; Olga Genbacev; Aras Mattis; Michael T McMaster; Ana Krtolica; Diana Valbuena; Carlos Simón; Louise C Laurent; Jeanne F Loring; Susan J Fisher
Journal:  Development       Date:  2015-10-19       Impact factor: 6.868

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  1 in total

1.  Why psychological accounts of personal identity can accept a brain death criterion and biological definition of death.

Authors:  David B Hershenov
Journal:  Theor Med Bioeth       Date:  2019-10
  1 in total

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