Efficacy of coarse spray administration of commercial intermediate infectious bursal disease vaccines.

The efficacy of two intermediate infectious bursal disease (IBD) vaccines (Clone Vac D-78 and S-706) for immunizing specific pathogen-free (SPF) White Leghorn chickens by coarse spray (CS) against subclinical IBD was compared. Both intermediate IBD vaccines were equally capable of immunizing day-old SPF chickens by CS and were safe as evidenced by the absence of morbidity, mortality, or severe gross and microscopic bursal pathology at 28 days of age.