Literature DB >> 3016658

Isolation of cDNA clones derived from a cellular gene transcriptionally induced by herpes simplex virus.

R Patel, W L Chan, L M Kemp, N B La Thangue, D S Latchman.   

Abstract

A small number of cellular proteins accumulate to high levels in cells infected with Herpes Simplex Virus (HSV) despite a generalised repression of most host cell bio-synthesis. An antibody to one such protein has been used to screen a lambda gt11 library and for polysome immunoprecipitation in order to isolate cDNA clones derived from the corresponding gene. The cDNA clones have been used in dot blot and nuclear run-off assays to show that HSV, like other DNA tumour viruses can transcriptionally induce a cellular gene. The mechanism of this effect which is dependent on viral protein synthesis and its possible significance in transformation by HSV are discussed.

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Year:  1986        PMID： 3016658      PMCID： PMC311581          DOI： 10.1093/nar/14.14.5629

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  22 in total

1.  Polyoma transformation of hamster cell clones--an investigation of genetic factors affecting cell competence.

Authors:  I MACPHERSON; M STOKER
Journal:  Virology       Date:  1962-02       Impact factor: 3.616

2.  An adenovirus type 5 early gene function regulates expression of other early viral genes.

Authors:  N Jones; T Shenk
Journal:  Proc Natl Acad Sci U S A       Date:  1979-08       Impact factor: 11.205

3.  Screening lambdagt recombinant clones by hybridization to single plaques in situ.

Authors:  W D Benton; R W Davis
Journal:  Science       Date:  1977-04-08       Impact factor: 47.728

4.  Identification of an SV40 DNA sequence related to the reactivation of silent rRNA genes in human greater than mouse hybrid cells.

Authors:  K J Soprano; G J Jonak; N Galanti; J Floros; R Baserga
Journal:  Virology       Date:  1981-02       Impact factor: 3.616

5.  The oncogenic potential of herpes simplex viruses: evidence for a 'hit-and-run' mechanism.

Authors:  D A Galloway; J K McDougall
Journal:  Nature       Date:  1983-03-03       Impact factor: 49.962

6.  Activation of gene expression by adenovirus and herpesvirus regulatory genes acting in trans and by a cis-acting adenovirus enhancer element.

Authors:  M J Imperiale; L T Feldman; J R Nevins
Journal:  Cell       Date:  1983-11       Impact factor: 41.582

7.  The 5' ends of Drosophila heat shock genes in chromatin are hypersensitive to DNase I.

Authors:  C Wu
Journal:  Nature       Date:  1980-08-28       Impact factor: 49.962

8.  Recovery of protein synthesis after heat shock: prior heat treatment affects the ability of cells to translate mRNA.

Authors:  N S Petersen; H K Mitchell
Journal:  Proc Natl Acad Sci U S A       Date:  1981-03       Impact factor: 11.205

9.  Herpes simplex virus-induced changes in cellular and adenovirus RNA metabolism in an adenovirus type 5-transformed human cell line.

Authors:  R M Stenberg; L I Pizer
Journal:  J Virol       Date:  1982-05       Impact factor: 5.103

10.  Inhibition of host protein synthesis and degradation of cellular mRNAs during infection by influenza and herpes simplex virus.

Authors:  S C Inglis
Journal:  Mol Cell Biol       Date:  1982-12       Impact factor: 4.272
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  19 in total

1.  Differential regulation of endogenous and transduced beta-globin genes during infection of erythroid cells with a herpes simplex virus type 1 recombinant.

Authors:  C A Smibert; J R Smiley
Journal:  J Virol       Date:  1990-08       Impact factor: 5.103

2.  The herpes simplex virus virion protein Vmw65 transcriptionally activates the gene encoding the U4 snRNA but not that encoding the U2 snRNA during lytic infection.

Authors:  D S Latchman
Journal:  Biochem J       Date:  1991-04-15       Impact factor: 3.857

3.  Inhibition of histone H2B gene transcription and of cellular growth by a truncated viral trans-activator protein.

Authors:  C L Dent; J K Estridge; L M Kemp; D S Latchman
Journal:  Mol Cell Biol       Date:  1990-06       Impact factor: 4.272

4.  Identification of a novel bovine herpesvirus type 1 immediate-early infected cell protein.

Authors:  M K Hayes; D L Rock
Journal:  Arch Virol       Date:  1990       Impact factor: 2.574

5.  The different competitive abilities of viral TAATGARAT elements and cellular octamer motifs, mediate the induction of viral immediate-early genes and the repression of the histone H2B gene in herpes simplex virus infected cells.

Authors:  D S Latchman; J F Partidge; J K Estridge; L M Kemp
Journal:  Nucleic Acids Res       Date:  1989-11-11       Impact factor: 16.971

6.  Stimulation of estrogen receptor mRNA levels in MCF-7 cells by herpes simplex virus infection.

Authors:  E A Offord; R E Leake; J C Macnab
Journal:  J Virol       Date:  1989-05       Impact factor: 5.103

7.  Expression of a cellular gene cloned in herpes simplex virus: rabbit beta-globin is regulated as an early viral gene in infected fibroblasts.

Authors:  J R Smiley; C Smibert; R D Everett
Journal:  J Virol       Date:  1987-08       Impact factor: 5.103

8.  Transcriptional induction of the ubiquitin gene during herpes simplex virus infection is dependent upon the viral immediate-early protein ICP4.

Authors:  D S Latchman; J K Estridge; L M Kemp
Journal:  Nucleic Acids Res       Date:  1987-09-25       Impact factor: 16.971

9.  Induction of interleukin-8 gene expression is associated with herpes simplex virus infection of human corneal keratocytes but not human corneal epithelial cells.

Authors:  J E Oakes; C A Monteiro; C L Cubitt; R N Lausch
Journal:  J Virol       Date:  1993-08       Impact factor: 5.103

10.  Activation of the cellular transcription factor AP-1 in herpes simplex virus infected cells is dependent on the viral immediate-early protein ICPO.

Authors:  K L Jang; B Pulverer; J R Woodgett; D S Latchman
Journal:  Nucleic Acids Res       Date:  1991-09-25       Impact factor: 16.971
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