Vinit Kumar Srivastava1, Sanjay Agrawal2, Sanjay Kumar3, Saima Khan1, Sunil Sharma4, Raj Kumar4. 1. Department of Anaesthesia, Apollo Hospitals Bilaspur (CG), India. 2. Department of Anaesthesia, Himalayan Institute of Medical Sciences, Dehradun (UK), India. 3. Department of Anaesthesia, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow (UP), India. 4. Department of Neurosurgery, Apollo Hospitals Bilaspur (CG), India.
Abstract
OBJECTIVE: Chronic subdural haematoma (CSDH) is a common neurosurgical problem, and treatment includes evacuation of the haematoma by burr hole drainage. Commonly, these procedures are performed under local anaesthesia, general anaesthesia or, recently, with monitored anaesthesia care (MAC). We compared dexmedetomidine- and propofol-based sedation along with scalp nerve block for burr hole evacuation of CSDH. METHODS: In this prospective randomised study, 62 patients were divided into the following two groups of 31 patients each: Group D and Group P. Group D received dexmedetomidine 1 μg kg-1 over 10 minutes as a loading dose, followed by 0.2-0.7 μg kg-1 hr-1. Group P received propofol 1 mg kg-1 over 10 minutes as a loading dose, followed by 1-3 mg kg-1 hr-1. The heart rate (HR) and blood pressure were measured at different intervals. The recovery parameter and satisfaction score were also recorded. RESULTS: There were no significant differences noted in the demographic profile. A significant decrease in HR compared to preoperative value was seen in Group D compared to Group P. Blood pressure values were statistically significantly lower in both study groups, compared to preoperative values during the whole procedure and after surgery (p<0.05). Time to achieve modified Aldrete score of 9-10 was not significantly different between the groups (p=0.354). Surgeon satisfaction was significantly better in Group D compared to Group P (p<0.05), but patient satisfaction was similar between the groups (p=0.364). CONCLUSION: Dexmedetomidine-based sedation compared to propofol, along with scalp block for MAC in patients undergoing burr hole evacuation of CSDH is associated with haemodynamic stability and greater surgeon satisfaction.
OBJECTIVE: Chronic subdural haematoma (CSDH) is a common neurosurgical problem, and treatment includes evacuation of the haematoma by burr hole drainage. Commonly, these procedures are performed under local anaesthesia, general anaesthesia or, recently, with monitored anaesthesia care (MAC). We compared dexmedetomidine- and propofol-based sedation along with scalp nerve block for burr hole evacuation of CSDH. METHODS: In this prospective randomised study, 62 patients were divided into the following two groups of 31 patients each: Group D and Group P. Group D received dexmedetomidine 1 μg kg-1 over 10 minutes as a loading dose, followed by 0.2-0.7 μg kg-1 hr-1. Group P received propofol 1 mg kg-1 over 10 minutes as a loading dose, followed by 1-3 mg kg-1 hr-1. The heart rate (HR) and blood pressure were measured at different intervals. The recovery parameter and satisfaction score were also recorded. RESULTS: There were no significant differences noted in the demographic profile. A significant decrease in HR compared to preoperative value was seen in Group D compared to Group P. Blood pressure values were statistically significantly lower in both study groups, compared to preoperative values during the whole procedure and after surgery (p<0.05). Time to achieve modified Aldrete score of 9-10 was not significantly different between the groups (p=0.354). Surgeon satisfaction was significantly better in Group D compared to Group P (p<0.05), but patient satisfaction was similar between the groups (p=0.364). CONCLUSION: Dexmedetomidine-based sedation compared to propofol, along with scalp block for MAC in patients undergoing burr hole evacuation of CSDH is associated with haemodynamic stability and greater surgeon satisfaction.
Authors: David Yuen Chung Chan; Peter Yat Ming Woo; Calvin Hoi Kwan Mak; Alberto Chi Ho Chu; Charles Churk Hang Li; Natalie Man Wai Ko; Stephanie Chi Ping Ng; Tin Fung David Sun; Wai Sang Poon Journal: J Clin Neurosci Date: 2016-11-30 Impact factor: 1.961
Authors: Anthony T Gerlach; Danielle M Blais; G Morgan Jones; Pamela K Burcham; Stanislaw P Stawicki; Charles H Cook; Claire V Murphy Journal: Int J Crit Illn Inj Sci Date: 2016 Jul-Sep