| Literature DB >> 3013267 |
S Sparrow, M Jones, S Billington, B Stace.
Abstract
During the routine serial passage of over 30 human tumour xenografts in athymic (nu. nu.) mice over a period of 6 years the induction of murine fibrosarcomas at the site of transplantation has been observed on three occasions. In two cases it has been possible to follow the development of these tumours over successive transplant generations. These sarcomas had growth rates, tumour karyotypes and isoenzyme patterns which clearly distinguished them from the original human xenografts.Entities:
Mesh:
Substances:
Year: 1986 PMID: 3013267 PMCID: PMC2001411 DOI: 10.1038/bjc.1986.134
Source DB: PubMed Journal: Br J Cancer ISSN: 0007-0920 Impact factor: 7.640