Literature DB >> 30121451

Gamma oscillations in cognitive disorders.

Alexandra J Mably1, Laura Lee Colgin2.   

Abstract

Gamma oscillations (∼25-100 Hz) are believed to play a role in cognition. Accordingly, aberrant gamma oscillations have been observed in several cognitive disorders, including Alzheimer's disease and Fragile X syndrome. Here, we review how recent results showing abnormal gamma rhythms in Alzheimer's disease and Fragile X syndrome help reveal links between cellular disturbances and cognitive impairments. We also discuss how gamma results from rodent models of Alzheimer's disease and Fragile X syndrome may provide insights about unique functions of distinct slow (∼25-50 Hz) and fast gamma (∼55-100 Hz) subtypes. Finally, we consider studies employing brain stimulation paradigms in Alzheimer's disease and discuss how such studies may reveal causal relationships between gamma impairments and memory disturbances.
Copyright © 2018 The Authors. Published by Elsevier Ltd.. All rights reserved.

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Year:  2018        PMID: 30121451      PMCID: PMC6139067          DOI: 10.1016/j.conb.2018.07.009

Source DB:  PubMed          Journal:  Curr Opin Neurobiol        ISSN: 0959-4388            Impact factor:   6.627


  52 in total

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4.  Impairments in spatial representations and rhythmic coordination of place cells in the 3xTg mouse model of Alzheimer's disease.

Authors:  Alexandra J Mably; Brian J Gereke; Dylan T Jones; Laura Lee Colgin
Journal:  Hippocampus       Date:  2017-01-16       Impact factor: 3.899

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Authors:  Clair A Booth; Jonathan Witton; Jakub Nowacki; Krasimira Tsaneva-Atanasova; Matthew W Jones; Andrew D Randall; Jonathan T Brown
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Authors:  L E Ethridge; S P White; M W Mosconi; J Wang; M J Byerly; J A Sweeney
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  38 in total

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7.  Perinatal Fentanyl Exposure Leads to Long-Lasting Impairments in Somatosensory Circuit Function and Behavior.

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8.  Computation of the electroencephalogram (EEG) from network models of point neurons.

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9.  Patient-Tailored, Home-Based Non-invasive Brain Stimulation for Memory Deficits in Dementia Due to Alzheimer's Disease.

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10.  Deficits in Early Sensory and Cognitive Processing Are Related to Phase and Nonphase EEG Activity in Multiple Sclerosis Patients.

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