Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Beyond Promoters: How Genes Tweak Their Own Expression.

Literature DB >> 30119990

Beyond Promoters: How Genes Tweak Their Own Expression.

Abstract

The correct expression of genes is vital for cells to function. Schikora-Tamarit et al. show that, in addition to obeying their promoters, most genes can modulate their own expression by either buffering or amplification. This could help to avoid costly overexpression of proteins.

Entities: Chemical Disease Gene Species

Mesh：

Substances：

Year: 2018 PMID： 30119990 PMCID： PMC7813552 DOI： 10.1016/j.tig.2018.07.002

Source DB: PubMed Journal: Trends Genet ISSN： 0168-9525 Impact factor: 11.639

Keyword Cloud
References

10 in total

1. Totally asymmetric exclusion process with extended objects: a model for protein synthesis.

Authors: Leah B Shaw; R K P Zia; Kelvin H Lee
Journal: Phys Rev E Stat Nonlin Soft Matter Phys Date: 2003-08-18

2. An evolutionarily conserved mechanism for controlling the efficiency of protein translation.

Authors: Tamir Tuller; Asaf Carmi; Kalin Vestsigian; Sivan Navon; Yuval Dorfan; John Zaborske; Tao Pan; Orna Dahan; Itay Furman; Yitzhak Pilpel
Journal: Cell Date: 2010-04-16 Impact factor: 41.582

Review 3. Stochasticity in gene expression: from theories to phenotypes.

Authors: Mads Kaern; Timothy C Elston; William J Blake; James J Collins
Journal: Nat Rev Genet Date: 2005-06 Impact factor: 53.242

4. Stochasticity and traffic jams in the transcription of ribosomal RNA: Intriguing role of termination and antitermination.

Authors: Stefan Klumpp; Terence Hwa
Journal: Proc Natl Acad Sci U S A Date: 2008-11-18 Impact factor: 11.205

Beyond Promoters: How Genes Tweak Their Own Expression.

1. Totally asymmetric exclusion process with extended objects: a model for protein synthesis.

2. An evolutionarily conserved mechanism for controlling the efficiency of protein translation.

Review 3. Stochasticity in gene expression: from theories to phenotypes.

4. Stochasticity and traffic jams in the transcription of ribosomal RNA: Intriguing role of termination and antitermination.

5. Collective Space-Sensing Coordinates Pattern Scaling in Engineered Bacteria.

6. Promoter Activity Buffering Reduces the Fitness Cost of Misregulation.

7. A synthetic gene circuit for measuring autoregulatory feedback control.

Review 8. Cellular decision making and biological noise: from microbes to mammals.

Review 9. Genetic determinants and cellular constraints in noisy gene expression.

10. Stress-response balance drives the evolution of a network module and its host genome.