Literature DB >> 3011775

The small subunits of calcium dependent proteases with different calcium sensitivities are identical.

H Kawasaki, S Imajoh, S Kawashima, H Hayashi, K Suzuki.   

Abstract

The small subunits of two calcium dependent proteases from rabbit with different calcium sensitivities were isolated by high performance liquid chromatography (HPLC) and their properties were compared. The isolated subunits were indistinguishable on polyacrylamide gel electrophoresis and HPLC. Their amino acid compositions were identical, and the peptides obtained on their digestion with lysyl-endopeptidase showed identical peptide maps on HPLC. Furthermore, the amino acid compositions and partial amino acid sequences of the corresponding peptides purified by HPLC were the same. These results indicate that the two calcium protease isozymes possess the same small subunit.

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Year:  1986        PMID: 3011775     DOI: 10.1093/oxfordjournals.jbchem.a135622

Source DB:  PubMed          Journal:  J Biochem        ISSN: 0021-924X            Impact factor:   3.387


  7 in total

1.  Biologically active monomeric and heterodimeric recombinant human calpain I produced using the baculovirus expression system.

Authors:  S L Meyer; D Bozyczko-Coyne; S K Mallya; C M Spais; R Bihovsky; J K Kaywooya; D M Lang; R W Scott; R Siman
Journal:  Biochem J       Date:  1996-03-01       Impact factor: 3.857

2.  Ca(2+)-binding domain VI of rat calpain is a homodimer in solution: hydrodynamic, crystallization and preliminary X-ray diffraction studies.

Authors:  H Blanchard; Y Li; M Cygler; C M Kay; J Simon; C Arthur; P L Davies; J S Elce
Journal:  Protein Sci       Date:  1996-03       Impact factor: 6.725

3.  The effects of autolysis on the structure of chicken calpain II.

Authors:  C Crawford; A C Willis; J Gagnon
Journal:  Biochem J       Date:  1987-12-01       Impact factor: 3.857

Review 4.  The calpain system and cancer.

Authors:  Sarah J Storr; Neil O Carragher; Margaret C Frame; Tim Parr; Stewart G Martin
Journal:  Nat Rev Cancer       Date:  2011-05       Impact factor: 60.716

5.  Expression of the calpain system is associated with poor clinical outcome in gastro-oesophageal adenocarcinomas.

Authors:  Sarah J Storr; Xuan Pu; Jillian Davis; Dileep Lobo; Alex M Reece-Smith; Simon L Parsons; Srinivasan Madhusudan; Stewart G Martin
Journal:  J Gastroenterol       Date:  2013-01-19       Impact factor: 7.527

6.  Calpain inhibitor calpeptin suppresses pancreatic cancer by disrupting cancer-stromal interactions in a mouse xenograft model.

Authors:  Masaki Yoshida; Yoshihiro Miyasaka; Kenoki Ohuchida; Takashi Okumura; Biao Zheng; Nobuhiro Torata; Hayato Fujita; Toshinaga Nabae; Tatsuya Manabe; Masaya Shimamoto; Takao Ohtsuka; Kazuhiro Mizumoto; Masafumi Nakamura
Journal:  Cancer Sci       Date:  2016-09-24       Impact factor: 6.716

7.  Elevated Expression of Calpain-4 Predicts Poor Prognosis in Patients with Gastric Cancer after Gastrectomy.

Authors:  Peike Peng; Lingqiang Min; Shushu Song; Junjie Zhao; Lili Li; Caiting Yang; Miaomiao Shao; Mingming Zhang; Hao Wu; Jie Zhang; Can Li; Xuefei Wang; Hongshan Wang; Jing Qin; Yuanyuan Ruan; Jianxin Gu
Journal:  Int J Mol Sci       Date:  2016-09-27       Impact factor: 5.923

  7 in total

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