Literature DB >> 3011365

Evaluation of the immunostimulating activity of erythromycin in man.

F Fraschini, F Scaglione, F Ferrara, O Marelli, P C Braga, F Teodori.   

Abstract

The effects of erythromycin on the immune system have been studied in healthy volunteers and patients suffering from chronic bronchopneumonial diseases, by means of the following assays: phagocytosis, natural killer activity and superoxide anion production. The tests were performed before and after oral administration of 1 g of erythromycin. The findings suggest that erythromycin enhances phagocytosis by means of increasing ingestion of microorganisms, superoxide anion (O2-) production as well as natural killer activity. Under the experimental conditions described these effects appear 4-6 h after drug intake and reach their maximum around the 8th hour.

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Year:  1986        PMID： 3011365     DOI： 10.1159/000238425

Source DB:  PubMed          Journal:  Chemotherapy        ISSN： 0009-3157            Impact factor:   2.544


  7 in total

1.  Efficacy of erythromycin lactobionate for treating Pseudomonas aeruginosa bacteremia in mice.

Authors:  Y Hirakata; M Kaku; K Tomono; K Tateda; N Furuya; T Matsumoto; R Araki; K Yamaguchi
Journal:  Antimicrob Agents Chemother       Date:  1992-06       Impact factor: 5.191

2.  Direct evidence for antipseudomonal activity of macrolides: exposure-dependent bactericidal activity and inhibition of protein synthesis by erythromycin, clarithromycin, and azithromycin.

Authors:  K Tateda; Y Ishii; T Matsumoto; N Furuya; M Nagashima; T Matsunaga; A Ohno; S Miyazaki; K Yamaguchi
Journal:  Antimicrob Agents Chemother       Date:  1996-10       Impact factor: 5.191

3.  Macrolide antibiotics protect against endotoxin-induced vascular leakage and neutrophil accumulation in rat trachea.

Authors:  J Tamaoki; N Sakai; E Tagaya; K Konno
Journal:  Antimicrob Agents Chemother       Date:  1994-07       Impact factor: 5.191

4.  Effects of sub-MICs of erythromycin and other macrolide antibiotics on serum sensitivity of Pseudomonas aeruginosa.

Authors:  K Tateda; Y Hirakata; N Furuya; A Ohno; K Yamaguchi
Journal:  Antimicrob Agents Chemother       Date:  1993-04       Impact factor: 5.191

5.  Potential effects of erythromycin on host defense systems and virulence of Pseudomonas aeruginosa.

Authors:  Y Hirakata; M Kaku; R Mizukane; K Ishida; N Furuya; T Matsumoto; K Tateda; K Yamaguchi
Journal:  Antimicrob Agents Chemother       Date:  1992-09       Impact factor: 5.191

6.  Comparative in vitro exoenzyme-suppressing activities of azithromycin and other macrolide antibiotics against Pseudomonas aeruginosa.

Authors:  R Mizukane; Y Hirakata; M Kaku; Y Ishii; N Furuya; K Ishida; H Koga; S Kohno; K Yamaguchi
Journal:  Antimicrob Agents Chemother       Date:  1994-03       Impact factor: 5.938

Review 7.  Treatment of cats with feline infectious peritonitis.

Authors:  Katrin Hartmann; Susanne Ritz
Journal:  Vet Immunol Immunopathol       Date:  2008-01-19       Impact factor: 2.046
  7 in total

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