Literature DB >> 30107172

Cancer-Specific Splicing Changes and the Potential for Splicing-Derived Neoantigens.

Luisa Escobar Hoyos1, Omar Abdel-Wahab2.   

Abstract

In this issue of Cancer Cell, Kahles et al. perform a comprehensive analysis of RNA splicing across cancer types and identify novel correlations between genetic alterations and splicing in cancer. In addition, they identify that tumor-specific splicing has the potential to generate a large new class of tumor-specific neoantigens.
Copyright © 2018 Elsevier Inc. All rights reserved.

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Year:  2018        PMID： 30107172      PMCID： PMC6614861          DOI： 10.1016/j.ccell.2018.07.008

Source DB:  PubMed          Journal:  Cancer Cell        ISSN： 1535-6108            Impact factor:   31.743


  9 in total

1.  Differential expression of novel naturally occurring splice variants of PTEN and their functional consequences in Cowden syndrome and sporadic breast cancer.

Authors:  Shipra Agrawal; Charis Eng
Journal:  Hum Mol Genet       Date:  2006-01-25       Impact factor: 6.150

2.  Identification of common genetic variants controlling transcript isoform variation in human whole blood.

Authors:  Xiaoling Zhang; Roby Joehanes; Brian H Chen; Tianxiao Huan; Saixia Ying; Peter J Munson; Andrew D Johnson; Daniel Levy; Christopher J O'Donnell
Journal:  Nat Genet       Date:  2015-02-16       Impact factor: 38.330

3.  Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 Patients.

Authors:  André Kahles; Kjong-Van Lehmann; Nora C Toussaint; Matthias Hüser; Stefan G Stark; Timo Sachsenberg; Oliver Stegle; Oliver Kohlbacher; Chris Sander; Gunnar Rätsch
Journal:  Cancer Cell       Date:  2018-08-02       Impact factor: 31.743

4.  The Functional Impact of Alternative Splicing in Cancer.

Authors:  Héctor Climente-González; Eduard Porta-Pardo; Adam Godzik; Eduardo Eyras
Journal:  Cell Rep       Date:  2017-08-29       Impact factor: 9.423

5.  Noisy splicing drives mRNA isoform diversity in human cells.

Authors:  Joseph K Pickrell; Athma A Pai; Yoav Gilad; Jonathan K Pritchard
Journal:  PLoS Genet       Date:  2010-12-09       Impact factor: 5.917

6.  SplAdder: identification, quantification and testing of alternative splicing events from RNA-Seq data.

Authors:  André Kahles; Cheng Soon Ong; Yi Zhong; Gunnar Rätsch
Journal:  Bioinformatics       Date:  2016-02-11       Impact factor: 6.937

7.  Detection of Proteome Diversity Resulted from Alternative Splicing is Limited by Trypsin Cleavage Specificity.

Authors:  Xiaojing Wang; Simona G Codreanu; Bo Wen; Kai Li; Matthew C Chambers; Daniel C Liebler; Bing Zhang
Journal:  Mol Cell Proteomics       Date:  2017-12-08       Impact factor: 5.911

8.  Somatic Mutational Landscape of Splicing Factor Genes and Their Functional Consequences across 33 Cancer Types.

Authors:  Michael Seiler; Shouyong Peng; Anant A Agrawal; James Palacino; Teng Teng; Ping Zhu; Peter G Smith; Silvia Buonamici; Lihua Yu
Journal:  Cell Rep       Date:  2018-04-03       Impact factor: 9.423

9.  Systematic Analysis of Splice-Site-Creating Mutations in Cancer.

Authors:  Reyka G Jayasinghe; Song Cao; Qingsong Gao; Michael C Wendl; Nam Sy Vo; Sheila M Reynolds; Yanyan Zhao; Héctor Climente-González; Shengjie Chai; Fang Wang; Rajees Varghese; Mo Huang; Wen-Wei Liang; Matthew A Wyczalkowski; Sohini Sengupta; Zhi Li; Samuel H Payne; David Fenyö; Jeffrey H Miner; Matthew J Walter; Benjamin Vincent; Eduardo Eyras; Ken Chen; Ilya Shmulevich; Feng Chen; Li Ding
Journal:  Cell Rep       Date:  2018-04-03       Impact factor: 9.423
  9 in total
  18 in total

Review 1.  Alternative splicing of lncRNAs in human diseases.

Authors:  Jiaxi Chen; Yawen Liu; Jingyu Min; Huizhi Wang; Feifan Li; Chunhui Xu; Aihua Gong; Min Xu
Journal:  Am J Cancer Res       Date:  2021-03-01       Impact factor: 6.166

Review 2.  RNA-biology ruling cancer progression? Focus on 3'UTRs and splicing.

Authors:  Ayse Elif Erson-Bensan
Journal:  Cancer Metastasis Rev       Date:  2020-09       Impact factor: 9.264

Review 3.  Computational cancer neoantigen prediction: current status and recent advances.

Authors:  G Fotakis; Z Trajanoski; D Rieder
Journal:  Immunooncol Technol       Date:  2021-11-20

Review 4.  Targeting Aberrant Splicing in Myelodysplastic Syndromes: Biologic Rationale and Clinical Opportunity.

Authors:  Andrew M Brunner; David P Steensma
Journal:  Hematol Oncol Clin North Am       Date:  2019-12-11       Impact factor: 3.722

5.  Differential alternative RNA splicing and transcription events between tumors from African American and White patients in The Cancer Genome Atlas.

Authors:  Muthana Al Abo; Terry Hyslop; Xiaodi Qin; Kouros Owzar; Daniel J George; Steven R Patierno; Jennifer A Freedman
Journal:  Genomics       Date:  2021-03-08       Impact factor: 5.736

6.  Improved methods for RNAseq-based alternative splicing analysis.

Authors:  Patrick Pirrotte; Nicholas J Schork; Rebecca F Halperin; Apurva Hegde; Jessica D Lang; Elizabeth A Raupach; Christophe Legendre; Winnie S Liang; Patricia M LoRusso; Aleksandar Sekulic; Jeffrey A Sosman; Jeffrey M Trent; Sampathkumar Rangasamy
Journal:  Sci Rep       Date:  2021-05-24       Impact factor: 4.996

Review 7.  Aberrant alternative splicing in breast cancer.

Authors:  Quan Yang; Jinyao Zhao; Wenjing Zhang; Dan Chen; Yang Wang
Journal:  J Mol Cell Biol       Date:  2019-10-25       Impact factor: 6.216

8.  Alternative splicing associated with cancer stemness in kidney renal clear cell carcinoma.

Authors:  Lixing Xiao; Guoying Zou; Rui Cheng; Pingping Wang; Kexin Ma; Huimin Cao; Wenyang Zhou; Xiyun Jin; Zhaochun Xu; Yan Huang; Xiaoyu Lin; Huan Nie; Qinghua Jiang
Journal:  BMC Cancer       Date:  2021-06-15       Impact factor: 4.430

9.  Systemic characterization of alternative splicing related to prognosis and immune infiltration in malignant mesothelioma.

Authors:  Jinzhi Lai; Hainan Yang; Tianwen Xu
Journal:  BMC Cancer       Date:  2021-07-22       Impact factor: 4.430

Review 10.  Computational Prediction and Validation of Tumor-Associated Neoantigens.

Authors:  Vladimir Roudko; Benjamin Greenbaum; Nina Bhardwaj
Journal:  Front Immunol       Date:  2020-01-24       Impact factor: 7.561
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