Aimee N C Campbell1, Celestina Barbosa-Leiker2, Mary Hatch-Maillette3, Sarah E Mennenga4, Martina Pavlicova5, Jennifer Scodes1, Tanya Saraiya6, Shannon G Mitchell7, John Rotrosen4, Patricia Novo4, Edward V Nunes1, Shelly F Greenfield8. 1. Department of Psychiatry and New York State Psychiatric Institute, Columbia University Medical Center, New York, New York. 2. College of Nursing, Washington State University, New York, New York. 3. Department of Psychiatry & Behavioral Sciences, Alcohol and Drug Abuse Institute, University of Washington, Seattle, Washington. 4. Department of Psychiatry, New York University School of Medicine, New York, New York. 5. Department of Biostatistics, Columbia University Mailman School of Public Health, New York, New York. 6. Derner School of Psychology, Adelphi University, Garden City, New York. 7. Friends Research Institute, Inc., Baltimore, Maryland. 8. Harvard Medical School Department of Psychiatry and McLean Hospital, Boston, Massachusetts.
Abstract
BACKGROUND & OBJECTIVES: We investigated gender differences in individuals with opioid use disorder (OUD) receiving inpatient services and entering a randomized controlled trial comparing extended-release naltrexone to buprenorphine. METHODS: Participants (N = 570) provided demographic, substance use, and psychiatric information. RESULTS: Women were significantly younger, more likely to identify as bisexual, live with a sexual partner, be financially dependent, and less likely employed. Women reported significantly greater psychiatric comorbidity and risk behaviors, shorter duration but similar age of onset of opioid use. DISCUSSION/ CONCLUSIONS: Findings underscore economic, psychiatric, and infection vulnerability among women with OUD. SCIENTIFIC SIGNIFICANCE: Interventions targeting these disparities should be explored, as women may face complicated treatment initiation, retention, and recovery. (Am J Addict 2018;27:465-470).
RCT Entities:
BACKGROUND & OBJECTIVES: We investigated gender differences in individuals with opioid use disorder (OUD) receiving inpatient services and entering a randomized controlled trial comparing extended-release naltrexone to buprenorphine. METHODS:Participants (N = 570) provided demographic, substance use, and psychiatric information. RESULTS:Women were significantly younger, more likely to identify as bisexual, live with a sexual partner, be financially dependent, and less likely employed. Women reported significantly greater psychiatric comorbidity and risk behaviors, shorter duration but similar age of onset of opioid use. DISCUSSION/ CONCLUSIONS: Findings underscore economic, psychiatric, and infection vulnerability among women with OUD. SCIENTIFIC SIGNIFICANCE: Interventions targeting these disparities should be explored, as women may face complicated treatment initiation, retention, and recovery. (Am J Addict 2018;27:465-470).
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