Angela Di Paola1, Noor Taweh1,2, Breanne E Biondi3, Ariadna Forray4, Cynthia A Frank1, Albert Shaw1, Sandra A Springer1,5. 1. Department of Internal Medicine, Section of Infectious Diseases, AIDS Program, Yale School of Medicine, New Haven, Connecticut, USA. 2. University of Connecticut, Storrs, Connecticut, USA. 3. Department of Health Law, Policy, and Management, Boston University School of Public Health, Boston, Massachusetts, USA. 4. Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut, USA. 5. Center for Interdisciplinary Research, Yale University School of Public Health, New Haven, Connecticut, USA.
Abstract
BACKGROUND AND OBJECTIVES: We evaluated gender differences among persons initiating medications for opioid use disorder (MOUD). METHODS: Analyses of baseline assessments for a study evaluating the impact of MOUD on outcomes included: demographics, DSM-5 diagnoses, depression severity, quality of life (QoL), and medication history (N = 125). RESULTS: When compared to men, women had a greater prevalence of generalized anxiety and posttraumatic stress disorders; and worse psychological QoL. Women were less likely to be prescribed psychiatric medications. DISCUSSION AND CONCLUSIONS: Women may benefit from tailored multidisciplinary programs with MOUD. SCIENTIFIC SIGNIFICANCE: This study identified that women with OUD seeking MOUD in the community had greater sedative hypnotic nonprescribed medication use and psychiatric comorbidity than men, all of which can contribute to poorer retention on MOUD and higher risk of morbidity and mortality. Thus, concurrent psychiatric disorder screening and treatment integrated with MOUD may improve retention on MOUD, opioid relapse and overdose for women.
BACKGROUND AND OBJECTIVES: We evaluated gender differences among persons initiating medications for opioid use disorder (MOUD). METHODS: Analyses of baseline assessments for a study evaluating the impact of MOUD on outcomes included: demographics, DSM-5 diagnoses, depression severity, quality of life (QoL), and medication history (N = 125). RESULTS: When compared to men, women had a greater prevalence of generalized anxiety and posttraumatic stress disorders; and worse psychological QoL. Women were less likely to be prescribed psychiatric medications. DISCUSSION AND CONCLUSIONS: Women may benefit from tailored multidisciplinary programs with MOUD. SCIENTIFIC SIGNIFICANCE: This study identified that women with OUD seeking MOUD in the community had greater sedative hypnotic nonprescribed medication use and psychiatric comorbidity than men, all of which can contribute to poorer retention on MOUD and higher risk of morbidity and mortality. Thus, concurrent psychiatric disorder screening and treatment integrated with MOUD may improve retention on MOUD, opioid relapse and overdose for women.
Authors: Marcela C Smid; Nicole M Stone; Laurie Baksh; Michelle P Debbink; Brett D Einerson; Michael W Varner; Adam J Gordon; Erin A S Clark Journal: Obstet Gynecol Date: 2019-06 Impact factor: 7.661
Authors: Jun Ma; Yan-Ping Bao; Ru-Jia Wang; Meng-Fan Su; Mo-Xuan Liu; Jin-Qiao Li; Louisa Degenhardt; Michael Farrell; Frederic C Blow; Mark Ilgen; Jie Shi; Lin Lu Journal: Mol Psychiatry Date: 2018-06-22 Impact factor: 15.992