Literature DB >> 30105167

Practice Current: When do you order ancillary tests to determine brain death?

Nathaniel M Robbins1, James L Bernat1.   

Abstract

Brain death has been accepted as a legal definition of death in most countries, but practices for determining brain death vary widely. One source of variation is in the use of ancillary tests to assist in the diagnosis of brain death. Through case-based discussions with 3 experts from 3 continents, this article discusses selected aspects of brain death, with a focus on the use of ancillary tests. In particular, we explore the following questions: Are ancillary tests necessary, or is the clinical examination sufficient? What ancillary tests are preferred, and under which circumstances? Are ancillary tests required when the primary mechanism of injury is brainstem injury? Should the family's wishes play a role in the need for ancillary tests? The same case-based questions were posed to the rest of our readership in an online survey, the preliminary results of which are also presented.

Entities:  

Year:  2018        PMID: 30105167      PMCID: PMC6075996          DOI: 10.1212/CPJ.0000000000000473

Source DB:  PubMed          Journal:  Neurol Clin Pract        ISSN: 2163-0402


  25 in total

1.  Bedside detection of awareness in the vegetative state: a cohort study.

Authors:  Damian Cruse; Srivas Chennu; Camille Chatelle; Tristan A Bekinschtein; Davinia Fernández-Espejo; John D Pickard; Steven Laureys; Adrian M Owen
Journal:  Lancet       Date:  2011-11-09       Impact factor: 79.321

2.  Evidence-based guideline update: determining brain death in adults: report of the Quality Standards Subcommittee of the American Academy of Neurology.

Authors:  Eelco F M Wijdicks; Panayiotis N Varelas; Gary S Gronseth; David M Greer
Journal:  Neurology       Date:  2010-06-08       Impact factor: 9.910

Review 3.  A review of ancillary tests in evaluating brain death.

Authors:  Manraj K S Heran; Navraj S Heran; Sam D Shemie
Journal:  Can J Neurol Sci       Date:  2008-09       Impact factor: 2.104

Review 4.  Ancillary testing in brain death.

Authors:  Andreas H Kramer
Journal:  Semin Neurol       Date:  2015-04-03       Impact factor: 3.420

5.  Brain death declaration: Practices and perceptions worldwide.

Authors:  Sarah Wahlster; Eelco F M Wijdicks; Pratik V Patel; David M Greer; J Claude Hemphill; Marco Carone; Farrah J Mateen
Journal:  Neurology       Date:  2015-04-08       Impact factor: 9.910

6.  Guidelines for the determination of death. Report of the medical consultants on the diagnosis of death to the President's Commission for the Study of Ethical Problems in Medicine and Biomedical and Behavioral Research.

Authors: 
Journal:  JAMA       Date:  1981-11-13       Impact factor: 56.272

7.  Brain death worldwide: accepted fact but no global consensus in diagnostic criteria.

Authors:  Eelco F M Wijdicks
Journal:  Neurology       Date:  2002-01-08       Impact factor: 9.910

8.  Clinical report—Guidelines for the determination of brain death in infants and children: an update of the 1987 task force recommendations.

Authors:  Thomas A Nakagawa; Stephen Ashwal; Mudit Mathur; Mohan Mysore
Journal:  Pediatrics       Date:  2011-08-28       Impact factor: 7.124

9.  Brain death and the historical understanding of bioethics.

Authors:  Gary S Belkin
Journal:  J Hist Med Allied Sci       Date:  2003-07       Impact factor: 2.088

10.  An interdisciplinary response to contemporary concerns about brain death determination.

Authors:  Ariane Lewis; James L Bernat; Sandralee Blosser; Richard J Bonnie; Leon G Epstein; John Hutchins; Matthew P Kirschen; Michael Rubin; James A Russell; Justin A Sattin; Eelco F M Wijdicks; David M Greer
Journal:  Neurology       Date:  2018-01-31       Impact factor: 9.910

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  4 in total

1.  Author Response: Practice Current: When do you order ancillary tests to determine brain death?

Authors:  Nathaniel M Robbins; James L Bernat
Journal:  Neurol Clin Pract       Date:  2018-10

Review 2.  Pediatric brain death certification: a narrative review.

Authors:  Nina Fainberg; Leslie Mataya; Matthew Kirschen; Wynne Morrison
Journal:  Transl Pediatr       Date:  2021-10

3.  Exclusive color-coded duplex sonography of extracranial vessels reliably confirms brain death: A prospective study.

Authors:  Johann Lambeck; Christoph Strecker; Wolf-Dirk Niesen; Jürgen Bardutzky
Journal:  Front Neurol       Date:  2022-09-23       Impact factor: 4.086

Review 4.  Practice Variability in Determination of Death by Neurologic Criteria for Adult Patients.

Authors:  Alexandra Junn; David Y Hwang
Journal:  Yale J Biol Med       Date:  2019-12-20
  4 in total

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