Literature DB >> 3010318

Control of cytochrome P1-450 gene expression: analysis of a dioxin-responsive enhancer system.

P B Jones, L K Durrin, D R Galeazzi, J P Whitlock.   

Abstract

We analyzed the function and sequence of a dioxin-responsive genomic element flanking the 5' end of the cytochrome P1-450 gene in high-activity variant mouse hepatoma cells. The element can regulate the mouse mammary tumor virus promoter. The element retains responsiveness to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) when the distance, the 5' or 3' position, and/or the 5' or 3' orientation with respect to the promoter are varied. The function of the element requires TCDD-receptor complexes. The element remains responsive to TCDD when transfected into cells from either a heterologous mouse tissue or a heterologous species (human). The DNA element and TCDD receptors together constitute a dioxin-responsive enhancer system.

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Year:  1986        PMID: 3010318      PMCID: PMC323394          DOI: 10.1073/pnas.83.9.2802

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN: 0027-8424            Impact factor:   11.205


  18 in total

1.  Establishment and characterization of a cell line of human breast carcinoma origin.

Authors:  I Keydar; L Chen; S Karby; F R Weiss; J Delarea; M Radu; S Chaitcik; H J Brenner
Journal:  Eur J Cancer       Date:  1979-05       Impact factor: 9.162

2.  Establishment and characterization of a cloned line of C3H mouse embryo cells sensitive to postconfluence inhibition of division.

Authors:  C A Reznikoff; D W Brankow; C Heidelberger
Journal:  Cancer Res       Date:  1973-12       Impact factor: 12.701

Review 3.  The regulation of cytochrome P-450 gene expression.

Authors:  J P Whitlock
Journal:  Annu Rev Pharmacol Toxicol       Date:  1986       Impact factor: 13.820

4.  A new pair of M13 vectors for selecting either DNA strand of double-digest restriction fragments.

Authors:  J Messing; J Vieira
Journal:  Gene       Date:  1982-10       Impact factor: 3.688

Review 5.  2,3,7,8-tetrachlorodibenzo-p-dioxin and related halogenated aromatic hydrocarbons: examination of the mechanism of toxicity.

Authors:  A Poland; J C Knutson
Journal:  Annu Rev Pharmacol Toxicol       Date:  1982       Impact factor: 13.820

Review 6.  Magic enhancers?

Authors:  P Gruss
Journal:  DNA       Date:  1984

7.  Biochemical and genetic analysis of variant mouse hepatoma cells defective in the induction of benzo(a)pyrene-metabolizing enzyme activity.

Authors:  A G Miller; D Israel; J P Whitlock
Journal:  J Biol Chem       Date:  1983-03-25       Impact factor: 5.157

8.  Induction of mRNA specific for cytochrome P1-450 in wild type and variant mouse hepatoma cells.

Authors:  D I Israel; J P Whitlock
Journal:  J Biol Chem       Date:  1983-09-10       Impact factor: 5.157

9.  Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

Authors:  C M Gorman; L F Moffat; B H Howard
Journal:  Mol Cell Biol       Date:  1982-09       Impact factor: 4.272

10.  2,3,7,8-Tetrachlorodibenzo-p-dioxin receptors in wild type and variant mouse hepatoma cells. Nuclear location and strength of nuclear binding.

Authors:  J P Whitlock; D R Galeazzi
Journal:  J Biol Chem       Date:  1984-01-25       Impact factor: 5.157

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  34 in total

1.  Sensitivity to dioxin decreases as zebrafish mature.

Authors:  Kevin A Lanham; Richard E Peterson; Warren Heideman
Journal:  Toxicol Sci       Date:  2012-03-08       Impact factor: 4.849

2.  Glutathione S-transferase Ya subunit gene: identification of regulatory elements required for basal level and inducible expression.

Authors:  C A Telakowski-Hopkins; R G King; C B Pickett
Journal:  Proc Natl Acad Sci U S A       Date:  1988-02       Impact factor: 11.205

3.  Multiple DNA-binding factors interact with overlapping specificities at the aryl hydrocarbon response element of the cytochrome P450IA1 gene.

Authors:  F Saatcioglu; D J Perry; D S Pasco; J B Fagan
Journal:  Mol Cell Biol       Date:  1990-12       Impact factor: 4.272

4.  In situ protein-DNA interactions at a dioxin-responsive enhancer associated with the cytochrome P1-450 gene.

Authors:  L K Durrin; J P Whitlock
Journal:  Mol Cell Biol       Date:  1987-08       Impact factor: 4.272

5.  2,3,7,8-Tetrachlorodibenzo-p-dioxin-inducible aryl hydrocarbon receptor-mediated change in CYP1A1 chromatin structure occurs independently of transcription.

Authors:  L K Durrin; J P Whitlock
Journal:  Mol Cell Biol       Date:  1989-12       Impact factor: 4.272

6.  Simple and rapid yeast reporter bioassay for dioxin screening: evaluation of the dioxin-like compounds in industrial and municipal waste incineration plants.

Authors:  Masanobu Kawanishi; Kana Ohnisi; Hidetaka Takigami; Takashi Yagi
Journal:  Environ Sci Pollut Res Int       Date:  2012-09-30       Impact factor: 4.223

7.  Functional analysis of the transcriptional promoter for the CYP1A1 gene.

Authors:  K W Jones; J P Whitlock
Journal:  Mol Cell Biol       Date:  1990-10       Impact factor: 4.272

8.  The aromatic hydrocarbon receptor modulates the Hepa 1c1c7 cell cycle and differentiated state independently of dioxin.

Authors:  Q Ma; J P Whitlock
Journal:  Mol Cell Biol       Date:  1996-05       Impact factor: 4.272

9.  Expression of antisense RNA against initiation factor eIF-4E mRNA in HeLa cells results in lengthened cell division times, diminished translation rates, and reduced levels of both eIF-4E and the p220 component of eIF-4F.

Authors:  A De Benedetti; S Joshi-Barve; C Rinker-Schaeffer; R E Rhoads
Journal:  Mol Cell Biol       Date:  1991-11       Impact factor: 4.272

10.  Effect of dioxins on regulation of tyrosine hydroxylase gene expression by aryl hydrocarbon receptor: a neurotoxicology study.

Authors:  Eiichi Akahoshi; Seiko Yoshimura; Saeko Uruno; Mitsuko Ishihara-Sugano
Journal:  Environ Health       Date:  2009-06-06       Impact factor: 5.984

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