Literature DB >> 2823113

In situ protein-DNA interactions at a dioxin-responsive enhancer associated with the cytochrome P1-450 gene.

L K Durrin1, J P Whitlock.   

Abstract

We used an in situ exonuclease III protection technique (C. Wu, Nature [London] 309:229, 1984) to analyze protein-DNA interactions at a dioxin-responsive enhancer. Our results imply that the 2,3,7,8-tetrachlorodibenzo-p-dioxin-receptor complex interacts with the dioxin-responsive enhancer to activate transcription of the cytochrome P1-450 gene.

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Year:  1987        PMID: 2823113      PMCID: PMC367925          DOI: 10.1128/mcb.7.8.3008-3011.1987

Source DB:  PubMed          Journal:  Mol Cell Biol        ISSN: 0270-7306            Impact factor:   4.272


  17 in total

1.  Detection of specific sequences among DNA fragments separated by gel electrophoresis.

Authors:  E M Southern
Journal:  J Mol Biol       Date:  1975-11-05       Impact factor: 5.469

Review 2.  2,3,7,8-tetrachlorodibenzo-p-dioxin and related halogenated aromatic hydrocarbons: examination of the mechanism of toxicity.

Authors:  A Poland; J C Knutson
Journal:  Annu Rev Pharmacol Toxicol       Date:  1982       Impact factor: 13.820

3.  Two protein-binding sites in chromatin implicated in the activation of heat-shock genes.

Authors:  C Wu
Journal:  Nature       Date:  1984 May 17-23       Impact factor: 49.962

4.  Biochemical and genetic analysis of variant mouse hepatoma cells defective in the induction of benzo(a)pyrene-metabolizing enzyme activity.

Authors:  A G Miller; D Israel; J P Whitlock
Journal:  J Biol Chem       Date:  1983-03-25       Impact factor: 5.157

5.  Regulation of cytochrome P1-450 gene transcription by 2,3,7, 8-tetrachlorodibenzo-p-dioxin in wild type and variant mouse hepatoma cells.

Authors:  D I Israel; J P Whitlock
Journal:  J Biol Chem       Date:  1984-05-10       Impact factor: 5.157

6.  Induction of mRNA specific for cytochrome P1-450 in wild type and variant mouse hepatoma cells.

Authors:  D I Israel; J P Whitlock
Journal:  J Biol Chem       Date:  1983-09-10       Impact factor: 5.157

7.  Location of regulatory elements responsible for drug induction in the rat cytochrome P-450c gene.

Authors:  K Sogawa; A Fujisawa-Sehara; M Yamane; Y Fujii-Kuriyama
Journal:  Proc Natl Acad Sci U S A       Date:  1986-11       Impact factor: 11.205

8.  The Ah locus: correlation of intranuclear appearance of inducer-receptor complex with induction of cytochrome P1-450 mRNA.

Authors:  R H Tukey; R R Hannah; M Negishi; D W Nebert; H J Eisen
Journal:  Cell       Date:  1982-11       Impact factor: 41.582

9.  2,3,7,8-Tetrachlorodibenzo-p-dioxin receptors in wild type and variant mouse hepatoma cells. Nuclear location and strength of nuclear binding.

Authors:  J P Whitlock; D R Galeazzi
Journal:  J Biol Chem       Date:  1984-01-25       Impact factor: 5.157

10.  Chromatin structure, transcription, and methylation of the prolactin gene domain in pituitary tumors of Fischer 344 rats.

Authors:  L K Durrin; J L Weber; J Gorski
Journal:  J Biol Chem       Date:  1984-06-10       Impact factor: 5.157

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  8 in total

1.  2,3,7,8-Tetrachlorodibenzo-p-dioxin-inducible aryl hydrocarbon receptor-mediated change in CYP1A1 chromatin structure occurs independently of transcription.

Authors:  L K Durrin; J P Whitlock
Journal:  Mol Cell Biol       Date:  1989-12       Impact factor: 4.272

2.  Aryl hydrocarbon-induced interactions at multiple DNA elements of diverse sequence--a multicomponent mechanism for activation of cytochrome P4501A1 (CYP1A1) gene transcription.

Authors:  R W Robertson; L Zhang; D S Pasco; J B Fagan
Journal:  Nucleic Acids Res       Date:  1994-05-11       Impact factor: 16.971

3.  Liver cells contain constitutive DNase I-hypersensitive sites at the xenobiotic response elements 1 and 2 (XRE1 and -2) of the rat cytochrome P-450IA1 gene and a constitutive, nuclear XRE-binding factor that is distinct from the dioxin receptor.

Authors:  J Hapgood; S Cuthill; P Söderkvist; A Wilhelmsson; I Pongratz; R H Tukey; E F Johnson; J A Gustafsson; L Poellinger
Journal:  Mol Cell Biol       Date:  1991-09       Impact factor: 4.272

4.  Induction of the Cyp1a-1 dioxin-responsive enhancer in transgenic mice.

Authors:  S N Jones; P G Jones; H Ibarguen; C T Caskey; W J Craigen
Journal:  Nucleic Acids Res       Date:  1991-12-11       Impact factor: 16.971

Review 5.  Environmental pollutants and the immune response.

Authors:  Takafumi Suzuki; Takanori Hidaka; Yoshito Kumagai; Masayuki Yamamoto
Journal:  Nat Immunol       Date:  2020-10-12       Impact factor: 25.606

6.  Inducible, receptor-dependent protein-DNA interactions at a dioxin-responsive transcriptional enhancer.

Authors:  M S Denison; J M Fisher; J P Whitlock
Journal:  Proc Natl Acad Sci U S A       Date:  1988-04       Impact factor: 11.205

7.  Dioxin-dependent activation of murine Cyp1a-1 gene transcription requires protein kinase C-dependent phosphorylation.

Authors:  F Carrier; R A Owens; D W Nebert; A Puga
Journal:  Mol Cell Biol       Date:  1992-04       Impact factor: 4.272

Review 8.  Role of AHR Ligands in Skin Homeostasis and Cutaneous Inflammation.

Authors:  Nieves Fernández-Gallego; Francisco Sánchez-Madrid; Danay Cibrian
Journal:  Cells       Date:  2021-11-15       Impact factor: 6.600

  8 in total

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