| Literature DB >> 3010295 |
Abstract
Hybrids composed of phage M13 and plasmid pHV33 were used to study the formation of deletions in Escherichia coli. Eighty to ninety percent of the deletion endpoints were at the position of the nick introduced into the M13 replication origin by the phage gene II protein. This suggests the existence of a novel mechanism of illegitimate recombination.Entities:
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Year: 1986 PMID: 3010295 PMCID: PMC323518 DOI: 10.1073/pnas.83.10.3386
Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN: 0027-8424 Impact factor: 11.205