Deepali Savargaonkar1, Swati Sinha2, Bina Srivastava3, B N Nagpal4, Abhinav Sinha5, Arshad Shamim6, Ram Das7, Veena Pande8, Anupkumar R Anvikar9, Neena Valecha10. 1. National Institute of Malaria Research, Sector 8 Dwarka, New Delhi, 110077, India. Electronic address: dr.deepali27@gmail.com. 2. National Institute of Malaria Research, Sector 8 Dwarka, New Delhi, 110077, India. Electronic address: swati.microbio04@gmail.com. 3. National Institute of Malaria Research, Sector 8 Dwarka, New Delhi, 110077, India. Electronic address: shbira@gmail.com. 4. National Institute of Malaria Research, Sector 8 Dwarka, New Delhi, 110077, India. Electronic address: b_n_nagpal@hotmail.com. 5. National Institute of Malaria Research, Sector 8 Dwarka, New Delhi, 110077, India. Electronic address: aspsm2003@yahoo.co.in. 6. National Institute of Malaria Research, Sector 8 Dwarka, New Delhi, 110077, India. Electronic address: arshad.samim@yahoo.co.in. 7. National Institute of Malaria Research, Sector 8 Dwarka, New Delhi, 110077, India. Electronic address: ramdas9@gmail.com. 8. Kumaun University, Nainital, 263001, India. Electronic address: veena_kumaun@yahoo.co.in. 9. National Institute of Malaria Research, Sector 8 Dwarka, New Delhi, 110077, India. Electronic address: Anvikar@gmail.com. 10. National Institute of Malaria Research, Sector 8 Dwarka, New Delhi, 110077, India. Electronic address: neenavalecha@gmail.com.
Abstract
OBJECTIVES: To study the epidemiology of dengue with reference to serological, demographic profile, spatio-temporal distribution, vectors, circulating serotypes and coinfections. METHODS: Demographic data and presenting symptoms of fever cases reporting to the clinic were recorded. Suspected patients were tested for dengue, chikungunya and malaria. Dengue specific RT-PCR was performed to detect circulating DENV serotypes. Vector surveys were carried out to detect Aedes breeding. RESULTS: Of the 5536 fever patients tested during 2012 to 2015, 1536 (27.7%) had confirmed dengue. The peak in dengue positivity was observed during September and October. Of the 60 samples analysed, 10 (16.7%) had concurrent infection with multiple dengue serotypes; one of them had all the four serotypes. Coinfection of dengue with malaria and chikungunya was also observed. The occurrence of dengue and malaria was inversely related. Seven percent of the dengue patients required hospitalization. Vector surveys in the draining area revealed Aedes breeding with a high house index. CONCLUSION: Delhi being hyperendemic, the occurrence of concurrent infections with multiple DENV serotypes has become a frequent finding. The study emphasizes the need of epidemiological and entomological surveillance to monitor trends in dengue distribution, seasonal patterns and circulating serotypes to guide dengue control activities.
OBJECTIVES: To study the epidemiology of dengue with reference to serological, demographic profile, spatio-temporal distribution, vectors, circulating serotypes and coinfections. METHODS: Demographic data and presenting symptoms of fever cases reporting to the clinic were recorded. Suspected patients were tested for dengue, chikungunya and malaria. Dengue specific RT-PCR was performed to detect circulating DENV serotypes. Vector surveys were carried out to detect Aedes breeding. RESULTS: Of the 5536 feverpatients tested during 2012 to 2015, 1536 (27.7%) had confirmed dengue. The peak in dengue positivity was observed during September and October. Of the 60 samples analysed, 10 (16.7%) had concurrent infection with multiple dengue serotypes; one of them had all the four serotypes. Coinfection of dengue with malaria and chikungunya was also observed. The occurrence of dengue and malaria was inversely related. Seven percent of the dengue patients required hospitalization. Vector surveys in the draining area revealed Aedes breeding with a high house index. CONCLUSION: Delhi being hyperendemic, the occurrence of concurrent infections with multiple DENV serotypes has become a frequent finding. The study emphasizes the need of epidemiological and entomological surveillance to monitor trends in dengue distribution, seasonal patterns and circulating serotypes to guide dengue control activities.
Authors: Jyotirmayee Turuk; Subrata K Palo; Sonalika Rath; Subhra Subhadra; Jyotsnamayee Sabat; Prakash K Sahoo; Sailendra Panda; Sanghamitra Pati Journal: J Family Med Prim Care Date: 2021-08-27
Authors: Anh N Ly; Russell Manzanero; Adrianna Maliga; Sarah M Gunter; Shannon E Ronca; Emily Zielinski-Gutierrez; Francis Morey; Kim Bautista; Andres Espinosa-Bode; Beatriz López; Loren Cadena; Rafael C Fuentes; Timothy A Erickson; Flor M Munoz; Joy Mackey; Gerhaldine Morazán; Kristy O Murray Journal: Viruses Date: 2022-04-07 Impact factor: 5.048
Authors: P D N N Sirisena; Shakuntala Mahilkar; Chetan Sharma; Jaspreet Jain; Sujatha Sunil Journal: Indian J Med Res Date: 2021-05 Impact factor: 5.274