Literature DB >> 3009963

Detection of antibodies to HTLV-III in commercially available immunoglobulin preparations.

R Kurth, I Schmidt, A Werner, G von Wangenheim, J Löwer, H D Brede.   

Abstract

Samples of 96 polyvalent and virus-specific immunoglobulin batches commercially available in West-Germany were tested by enzyme-linked immunoassay and immunoblot for the presence of anti-HTLV-III antibodies. 37% of the polyvalent and 87% of the virus-specific batches were positive. It was concluded that these preparations are still safe and because of their reportedly low titer neutralizing antibodies possibly beneficial in certain cases, such as newborns of HTLV-III positive mothers or after accidental exposure to infectious material in clinics or laboratories.

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Year:  1986        PMID: 3009963     DOI: 10.1007/bf01728189

Source DB:  PubMed          Journal:  Klin Wochenschr        ISSN: 0023-2173


  8 in total

1.  Antibody to lymphadenopathy-associated virus in AIDS.

Authors:  D D Ho; T R Rota; M S Hirsch
Journal:  N Engl J Med       Date:  1985-03-07       Impact factor: 91.245

2.  Infection of HTLV-III/LAV in HTLV-I-carrying cells MT-2 and MT-4 and application in a plaque assay.

Authors:  S Harada; Y Koyanagi; N Yamamoto
Journal:  Science       Date:  1985-08-09       Impact factor: 47.728

3.  Update: prospective evaluation of health-care workers exposed via the parenteral or mucous-membrane route to blood or body fluids from patients with acquired immunodeficiency syndrome--United States.

Authors: 
Journal:  MMWR Morb Mortal Wkly Rep       Date:  1985-02-22       Impact factor: 17.586

4.  HTLV-III-neutralizing antibodies in patients with AIDS and AIDS-related complex.

Authors:  M Robert-Guroff; M Brown; R C Gallo
Journal:  Nature       Date:  1985 Jul 4-10       Impact factor: 49.962

5.  Neutralization of human T-lymphotropic virus type III by sera of AIDS and AIDS-risk patients.

Authors:  R A Weiss; P R Clapham; R Cheingsong-Popov; A G Dalgleish; C A Carne; I V Weller; R S Tedder
Journal:  Nature       Date:  1985 Jul 4-10       Impact factor: 49.962

6.  [Neutralizing virus antibodies in human immunoglobulins for intravenous use].

Authors:  M Weeke-Lüttmann; I Schmidt; A Fenyves; G von Wangenheim; L Fischer
Journal:  Immun Infekt       Date:  1984-08

7.  Methods in laboratory investigation. Application of the indirect enzyme-linked immunosorbent assay microtest to the detection and surveillance of human t cell leukemia-lymphoma virus.

Authors:  C Saxinger; R C Gallo
Journal:  Lab Invest       Date:  1983-09       Impact factor: 5.662

8.  [Human normal immunoglobulin, requirements for its safety and potency (author's transl)].

Authors:  W Schneider; P E Kaiser
Journal:  Immun Infekt       Date:  1981-09
  8 in total

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