Literature DB >> 30096310

Microbiome: Focus on Causation and Mechanism.

Michael A Fischbach1.   

Abstract

There is tremendous enthusiasm for the microbiome in academia and industry. This Perspective argues that in order to realize its potential, the field needs to focus on establishing causation and molecular mechanism with an emphasis on phenotypes that are large in magnitude, easy to measure, and unambiguously driven by the microbiota.
Copyright © 2018 Elsevier Inc. All rights reserved.

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Year:  2018        PMID: 30096310      PMCID: PMC6094951          DOI: 10.1016/j.cell.2018.07.038

Source DB:  PubMed          Journal:  Cell        ISSN: 0092-8674            Impact factor:   41.582


  58 in total

Review 1.  Intestinal Crosstalk between Bile Acids and Microbiota and Its Impact on Host Metabolism.

Authors:  Annika Wahlström; Sama I Sayin; Hanns-Ulrich Marschall; Fredrik Bäckhed
Journal:  Cell Metab       Date:  2016-06-16       Impact factor: 27.287

2.  Persistent microbiome alterations modulate the rate of post-dieting weight regain.

Authors:  Christoph A Thaiss; Shlomik Itav; Daphna Rothschild; Mariska T Meijer; Maayan Levy; Claudia Moresi; Lenka Dohnalová; Sofia Braverman; Shachar Rozin; Sergey Malitsky; Mally Dori-Bachash; Yael Kuperman; Inbal Biton; Arieh Gertler; Alon Harmelin; Hagit Shapiro; Zamir Halpern; Asaph Aharoni; Eran Segal; Eran Elinav
Journal:  Nature       Date:  2016-11-24       Impact factor: 49.962

3.  Specialized metabolites from the microbiome in health and disease.

Authors:  Gil Sharon; Neha Garg; Justine Debelius; Rob Knight; Pieter C Dorrestein; Sarkis K Mazmanian
Journal:  Cell Metab       Date:  2014-11-04       Impact factor: 27.287

4.  Oral administration of Parabacteroides distasonis antigens attenuates experimental murine colitis through modulation of immunity and microbiota composition.

Authors:  M Kverka; Z Zakostelska; K Klimesova; D Sokol; T Hudcovic; T Hrncir; P Rossmann; J Mrazek; J Kopecny; E F Verdu; H Tlaskalova-Hogenova
Journal:  Clin Exp Immunol       Date:  2010-11-19       Impact factor: 4.330

Review 5.  Metaorganismal nutrient metabolism as a basis of cardiovascular disease.

Authors:  J Mark Brown; Stanley L Hazen
Journal:  Curr Opin Lipidol       Date:  2014-02       Impact factor: 4.776

Review 6.  Resurrecting the intestinal microbiota to combat antibiotic-resistant pathogens.

Authors:  Eric G Pamer
Journal:  Science       Date:  2016-04-29       Impact factor: 47.728

7.  Host-derived nitrate boosts growth of E. coli in the inflamed gut.

Authors:  Sebastian E Winter; Maria G Winter; Mariana N Xavier; Parameth Thiennimitr; Victor Poon; A Marijke Keestra; Richard C Laughlin; Gabriel Gomez; Jing Wu; Sara D Lawhon; Ina E Popova; Sanjai J Parikh; L Garry Adams; Renée M Tsolis; Valley J Stewart; Andreas J Bäumler
Journal:  Science       Date:  2013-02-08       Impact factor: 47.728

8.  Treg induction by a rationally selected mixture of Clostridia strains from the human microbiota.

Authors:  Koji Atarashi; Takeshi Tanoue; Kenshiro Oshima; Wataru Suda; Yuji Nagano; Hiroyoshi Nishikawa; Shinji Fukuda; Takuro Saito; Seiko Narushima; Koji Hase; Sangwan Kim; Joëlle V Fritz; Paul Wilmes; Satoshi Ueha; Kouji Matsushima; Hiroshi Ohno; Bernat Olle; Shimon Sakaguchi; Tadatsugu Taniguchi; Hidetoshi Morita; Masahira Hattori; Kenya Honda
Journal:  Nature       Date:  2013-07-10       Impact factor: 49.962

9.  Precision microbiome reconstitution restores bile acid mediated resistance to Clostridium difficile.

Authors:  Charlie G Buffie; Vanni Bucci; Richard R Stein; Peter T McKenney; Lilan Ling; Asia Gobourne; Daniel No; Hui Liu; Melissa Kinnebrew; Agnes Viale; Eric Littmann; Marcel R M van den Brink; Robert R Jenq; Ying Taur; Chris Sander; Justin R Cross; Nora C Toussaint; Joao B Xavier; Eric G Pamer
Journal:  Nature       Date:  2014-10-22       Impact factor: 49.962

10.  Focused specificity of intestinal TH17 cells towards commensal bacterial antigens.

Authors:  Yi Yang; Miriam B Torchinsky; Michael Gobert; Huizhong Xiong; Mo Xu; Jonathan L Linehan; Francis Alonzo; Charles Ng; Alessandra Chen; Xiyao Lin; Andrew Sczesnak; Jia-Jun Liao; Victor J Torres; Marc K Jenkins; Juan J Lafaille; Dan R Littman
Journal:  Nature       Date:  2014-04-13       Impact factor: 49.962

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  64 in total

1.  Utility of Probiotics for Maintenance or Improvement of Health Status in Older People - A Scoping Review.

Authors:  E Setbo; K Campbell; P O'Cuiv; R Hubbard
Journal:  J Nutr Health Aging       Date:  2019       Impact factor: 4.075

2.  Causal effects in microbiomes using interventional calculus.

Authors:  Musfiqur Sazal; Vitalii Stebliankin; Kalai Mathee; Changwon Yoo; Giri Narasimhan
Journal:  Sci Rep       Date:  2021-03-11       Impact factor: 4.379

Review 3.  Conceptualizing the Vertebrate Sterolbiome.

Authors:  Jason M Ridlon
Journal:  Appl Environ Microbiol       Date:  2020-08-03       Impact factor: 4.792

Review 4.  Methods in Lung Microbiome Research.

Authors:  Sharon M Carney; Jose C Clemente; Michael J Cox; Robert P Dickson; Yvonne J Huang; Georgios D Kitsios; Kirsten M Kloepfer; Janice M Leung; Tricia D LeVan; Philip L Molyneaux; Bethany B Moore; David N O'Dwyer; Leopoldo N Segal; Stavros Garantziotis
Journal:  Am J Respir Cell Mol Biol       Date:  2020-03       Impact factor: 6.914

5.  Estimating and testing the microbial causal mediation effect with high-dimensional and compositional microbiome data.

Authors:  Chan Wang; Jiyuan Hu; Martin J Blaser; Huilin Li
Journal:  Bioinformatics       Date:  2020-01-15       Impact factor: 6.937

6.  Structure elucidation of colibactin and its DNA cross-links.

Authors:  Mengzhao Xue; Chung Sub Kim; Alan R Healy; Kevin M Wernke; Zhixun Wang; Madeline C Frischling; Emilee E Shine; Weiwei Wang; Seth B Herzon; Jason M Crawford
Journal:  Science       Date:  2019-08-08       Impact factor: 47.728

Review 7.  Chemical Reporters for Exploring Microbiology and Microbiota Mechanisms.

Authors:  Zhenrun J Zhang; Yen-Chih Wang; Xinglin Yang; Howard C Hang
Journal:  Chembiochem       Date:  2019-12-27       Impact factor: 3.164

8.  A Forward Chemical Genetic Screen Reveals Gut Microbiota Metabolites That Modulate Host Physiology.

Authors:  Haiwei Chen; Phu-Khat Nwe; Yi Yang; Connor E Rosen; Agata A Bielecka; Manik Kuchroo; Gary W Cline; Andrew C Kruse; Aaron M Ring; Jason M Crawford; Noah W Palm
Journal:  Cell       Date:  2019-04-18       Impact factor: 41.582

9.  Host-Microbe-Drug-Nutrient Screen Identifies Bacterial Effectors of Metformin Therapy.

Authors:  Rosina Pryor; Povilas Norvaisas; Georgios Marinos; Lena Best; Louise B Thingholm; Leonor M Quintaneiro; Wouter De Haes; Daniela Esser; Silvio Waschina; Celia Lujan; Reuben L Smith; Timothy A Scott; Daniel Martinez-Martinez; Orla Woodward; Kevin Bryson; Matthias Laudes; Wolfgang Lieb; Riekelt H Houtkooper; Andre Franke; Liesbet Temmerman; Ivana Bjedov; Helena M Cochemé; Christoph Kaleta; Filipe Cabreiro
Journal:  Cell       Date:  2019-08-29       Impact factor: 41.582

10.  Probiotic Exopolysaccharide Protects against Systemic Staphylococcus aureus Infection, Inducing Dual-Functioning Macrophages That Restrict Bacterial Growth and Limit Inflammation.

Authors:  Wonbeom Paik; Francis Alonzo; Katherine L Knight
Journal:  Infect Immun       Date:  2018-12-19       Impact factor: 3.441

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