Natalia Rangel Palmier1, Cristhian Camilo Madrid2, Mariana de Pauli Paglioni1, César Rivera3, Beatriz Nascimento F Lebre Martins1, Anna Luíza Damaceno Araújo1, João Victor Salvajoli4, Mario Fernando de Goes5, Marcio Ajudarte Lopes1, Ana Carolina Prado Ribeiro6, Thaís Bianca Brandão7, Alan Roger Santos-Silva8. 1. Oral Diagnosis, Piracicaba Dental School, UNICAMP, Brazil. 2. Oral Diagnosis, Piracicaba Dental School, UNICAMP, Brazil; Restorative Dentistry Departments, Piracicaba Dental School, UNICAMP, Brazil. 3. Oral Diagnosis, Piracicaba Dental School, UNICAMP, Brazil; Department of Basic Biomedical Sciences, Universidad de Talca, Chile. 4. Radiotherapy Service, Instituto do Câncer do Estado de São Paulo, ICESP-FMUSP, Brazil. 5. Restorative Dentistry Departments, Piracicaba Dental School, UNICAMP, Brazil. 6. Oral Diagnosis, Piracicaba Dental School, UNICAMP, Brazil; Dental Oncology Service, Instituto do Câncer do Estado de São Paulo, ICESP-FMUSP, Brazil; Universidade Brasil, Fernandópolis, Brazil. 7. Oral Diagnosis, Piracicaba Dental School, UNICAMP, Brazil; Dental Oncology Service, Instituto do Câncer do Estado de São Paulo, ICESP-FMUSP, Brazil. 8. Oral Diagnosis, Piracicaba Dental School, UNICAMP, Brazil; Dental Oncology Service, Instituto do Câncer do Estado de São Paulo, ICESP-FMUSP, Brazil. Electronic address: Alanroger@fop.unicamp.br.
Abstract
OBJECTIVES: The aim of this study was to assess the presence of enamel craze lines (ECLs), part of the spectrum of the so-called cracked tooth syndrome, on the surface of teeth irradiated in vivo. STUDY DESIGN: Forty teeth extracted from patients with head and neck cancer were paired, matched, and equally divided into 4 groups: noncarious irradiated (G1); noncarious control (G2); radiation-related caries (RRC) (G3), and carious control (G4). Samples were examined for ECL detection with a fiberoptic transillumination device and photographed, and ECL mean size, number, and patterns of topographic distribution in tooth crown were determined. Groups were compared accordingly: G1 versus G2; G3 versus G4. RESULTS: We analyzed 538 ECLs, of which 30.1% were found in noncarious irradiated teeth, 19.3% in noncarious controls, 27.6% in RRC, and 23% in carious controls. Non-carious irradiated teeth presented higher quantities of ECL than non-carious control (P < 0.05). Higher incidences of ECLs were identified in specific enamel topographies of anterior G1 and G3 samples (P <.05). There was no correlation between ECL size/numbers and radiation isodose delivery to teeth. CONCLUSIONS: Increased incidence of ECLs may indicate weakened enamel structure in irradiated teeth, and this may play a role in the onset and progression of RRC.
OBJECTIVES: The aim of this study was to assess the presence of enamel craze lines (ECLs), part of the spectrum of the so-called cracked tooth syndrome, on the surface of teeth irradiated in vivo. STUDY DESIGN: Forty teeth extracted from patients with head and neck cancer were paired, matched, and equally divided into 4 groups: noncarious irradiated (G1); noncarious control (G2); radiation-related caries (RRC) (G3), and carious control (G4). Samples were examined for ECL detection with a fiberoptic transillumination device and photographed, and ECL mean size, number, and patterns of topographic distribution in tooth crown were determined. Groups were compared accordingly: G1 versus G2; G3 versus G4. RESULTS: We analyzed 538 ECLs, of which 30.1% were found in noncarious irradiated teeth, 19.3% in noncarious controls, 27.6% in RRC, and 23% in carious controls. Non-carious irradiated teeth presented higher quantities of ECL than non-carious control (P < 0.05). Higher incidences of ECLs were identified in specific enamel topographies of anterior G1 and G3 samples (P <.05). There was no correlation between ECL size/numbers and radiation isodose delivery to teeth. CONCLUSIONS: Increased incidence of ECLs may indicate weakened enamel structure in irradiated teeth, and this may play a role in the onset and progression of RRC.
Authors: Mariana de Pauli Paglioni; Natalia Rangel Palmier; Ana Carolina Prado-Ribeiro; Eduardo Rodrigues Fregnani; Maria Beatriz Duarte Gavião; Thaís Bianca Brandão; Marcio Ajudarte Lopes; Ana Paula Dias Ribeiro; Cesar Augusto Migliorati; Alan Roger Santos-Silva Journal: Support Care Cancer Date: 2019-11-27 Impact factor: 3.603