Literature DB >> 30074284

Influence of the Membrane Dye R18 and of DMSO on Cell Penetration of Guanidinium-Rich Peptides.

Felix Kurth1, Petra S Dittrich1, Peter Walde2, Dieter Seebach3.   

Abstract

A quantitative analysis by confocal fluorescence microscopy of the entry into HEK293 and MCF-7 cells by fluorescein-labeled octaarginine (1) and by three octa-Adp derivatives (2 - 4, octamers of the β-Asp-Arg-dipeptide, derived from the biopolymer cyanophycin) is described, including the effects of the membrane dye R18 and of DMSO on cell penetration.
© 2018 Wiley-VHCA AG, Zurich, Switzerland.

Entities:  

Keywords:  DMSO; confocal fluorescence microscopy; cyanophycin; guanidinium-rich cell penetrating peptides (CPPs); membrane dye R18; octa-Adp; octaarginine; quantitative CPP analysis

Mesh：

Substances：

Year:  2018        PMID： 30074284      PMCID： PMC6387783          DOI： 10.1002/cbdv.201800302

Source DB:  PubMed          Journal:  Chem Biodivers        ISSN： 1612-1872            Impact factor:   2.408


  31 in total

1.  Cellular uptake studies with beta-peptides.

Authors:  Magnus Rueping; Yogesh Mahajan; Markus Sauer; Dieter Seebach
Journal:  Chembiochem       Date:  2002-03-01       Impact factor: 3.164

2.  Lipid peroxides promote large rafts: effects of excitation of probes in fluorescence microscopy and electrochemical reactions during vesicle formation.

Authors:  Artem G Ayuyan; Fredric S Cohen
Journal:  Biophys J       Date:  2006-06-30       Impact factor: 4.033

3.  Chemical and biological investigations of beta-oligoarginines.

Authors:  Dieter Seebach; Kenji Namoto; Yogesh R Mahajan; Pascal Bindschädler; Reiner Sustmann; Michael Kirsch; Neil S Ryder; Markus Weiss; Markus Sauer; Christian Roth; Sabine Werner; Hans-Dietmar Beer; Christine Munding; Peter Walde; Matthias Voser
Journal:  Chem Biodivers       Date:  2004-01       Impact factor: 2.408

4.  Low concentration of DMSO stabilizes the bilayer gel phase rather than the interdigitated gel phase in dihexadecylphosphatidylcholine membrane.

Authors:  Y Yamashita; K Kinoshita; M Yamazaki
Journal:  Biochim Biophys Acta       Date:  2000-08-25

5.  Preferential interaction of dimethyl sulfoxide and phosphatidyl choline membranes.

Authors:  Peter Westh
Journal:  Biochim Biophys Acta       Date:  2004-08-30

Review 6.  Investigation on lipid asymmetry using lipid probes: Comparison between spin-labeled lipids and fluorescent lipids.

Authors:  Philippe F Devaux; Pierre Fellmann; Paulette Hervé
Journal:  Chem Phys Lipids       Date:  2002-06       Impact factor: 3.329

7.  Modulating the structure and properties of cell membranes: the molecular mechanism of action of dimethyl sulfoxide.

Authors:  Andrey A Gurtovenko; Jamshed Anwar
Journal:  J Phys Chem B       Date:  2007-07-28       Impact factor: 2.991

8.  Fluorescence probe partitioning between Lo/Ld phases in lipid membranes.

Authors:  Tobias Baumgart; Geoff Hunt; Elaine R Farkas; Watt W Webb; Gerald W Feigenson
Journal:  Biochim Biophys Acta       Date:  2007-05-21

9.  Phase studies of model biomembranes: macroscopic coexistence of Lalpha+Lbeta, with light-induced coexistence of Lalpha+Lo Phases.

Authors:  Jiang Zhao; Jing Wu; Huilin Shao; Fanrong Kong; Nieraj Jain; Geoffrey Hunt; Gerald Feigenson
Journal:  Biochim Biophys Acta       Date:  2007-07-25

10.  Molecular simulation study on the influence of dimethylsulfoxide on the structure of phospholipid bilayers.

Authors:  Amadeu K Sum; Juan J de Pablo
Journal:  Biophys J       Date:  2003-12       Impact factor: 4.033
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  3 in total

1.  Encoding with a fluorescence-activating and absorption-shifting tag generates living bacterial probes for mammalian microbiota imaging.

Authors:  Zhenping Cao; Lu Wang; Rui Liu; Sisi Lin; Feng Wu; Jinyao Liu
Journal:  Mater Today Bio       Date:  2022-06-06

2.  Cell Penetration, Herbicidal Activity, and in-vivo-Toxicity of Oligo-Arginine Derivatives and of Novel Guanidinium-Rich Compounds Derived from the Biopolymer Cyanophycin.

Authors:  Marcel Grogg; Donald Hilvert; Marc-Olivier Ebert; Albert K Beck; Dieter Seebach; Felix Kurth; Petra S Dittrich; Christof Sparr; Sergio Wittlin; Matthias Rottmann; Pascal Mäser
Journal:  Helv Chim Acta       Date:  2018-10       Impact factor: 2.164

3.  Tunable Membrane Potential Reconstituted in Giant Vesicles Promotes Permeation of Cationic Peptides at Nanomolar Concentrations.

Authors:  Chao-Chen Lin; Michael Bachmann; Simon Bachler; Koushik Venkatesan; Petra S Dittrich
Journal:  ACS Appl Mater Interfaces       Date:  2018-12-03       Impact factor: 9.229
  3 in total

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