Literature DB >> 30072558

Common haemostasis issues in major bleeding and critical illness.

Divyansh Gulati1, Alex Novak1, Simon J Stanworth2.   

Abstract

Haemostatic abnormalities are common in the critically ill or bleeding patient, including haemorrhage-related coagulopathies, disseminated intravascular coagulation and thrombocytopenia, among other pathologies. In this article we aim to outline some of the causes of these clotting abnormalities, highlighting recent advancements in knowledge and new insights into their clinical management, with the aim of optimising diagnostic and therapeutic strategies. © Royal College of Physicians 2018. All rights reserved.

Entities:  

Keywords:  Major haemorrhage; coagulopathy; disseminated intravascular coagulation

Mesh：

Year:  2018        PMID： 30072558      PMCID： PMC6334047          DOI： 10.7861/clinmedicine.18-4-320

Source DB:  PubMed          Journal:  Clin Med (Lond)        ISSN： 1470-2118            Impact factor:   2.659


  24 in total

1.  Clotting factor deficiency in early trauma-associated coagulopathy.

Authors:  Sandro B Rizoli; Sandro Scarpelini; Jeannie Callum; Bartolomeu Nascimento; Kenneth G Mann; Ruxandra Pinto; Jan Jansen; Homer C Tien
Journal:  J Trauma       Date:  2011-11

2.  Transfusion of plasma, platelets, and red blood cells in a 1:1:1 vs a 1:1:2 ratio and mortality in patients with severe trauma: the PROPPR randomized clinical trial.

Authors:  John B Holcomb; Barbara C Tilley; Sarah Baraniuk; Erin E Fox; Charles E Wade; Jeanette M Podbielski; Deborah J del Junco; Karen J Brasel; Eileen M Bulger; Rachael A Callcut; Mitchell Jay Cohen; Bryan A Cotton; Timothy C Fabian; Kenji Inaba; Jeffrey D Kerby; Peter Muskat; Terence O'Keeffe; Sandro Rizoli; Bryce R H Robinson; Thomas M Scalea; Martin A Schreiber; Deborah M Stein; Jordan A Weinberg; Jeannie L Callum; John R Hess; Nena Matijevic; Christopher N Miller; Jean-Francois Pittet; David B Hoyt; Gail D Pearson; Brian Leroux; Gerald van Belle
Journal:  JAMA       Date:  2015-02-03       Impact factor: 56.272

Review 3.  Disseminated intravascular coagulation: objective clinical and laboratory diagnosis, treatment, and assessment of therapeutic response.

Authors:  R L Bick
Journal:  Semin Thromb Hemost       Date:  1996       Impact factor: 4.180

4.  A practical guideline for the haematological management of major haemorrhage.

Authors:  Beverley J Hunt; Shubha Allard; David Keeling; Derek Norfolk; Simon J Stanworth; Kate Pendry
Journal:  Br J Haematol       Date:  2015-07-06       Impact factor: 6.998

5.  Activated Protein C Drives the Hyperfibrinolysis of Acute Traumatic Coagulopathy.

Authors:  Ross A Davenport; Maria Guerreiro; Daniel Frith; Claire Rourke; Sean Platton; Mitchell Cohen; Rupert Pearse; Chris Thiemermann; Karim Brohi
Journal:  Anesthesiology       Date:  2017-01       Impact factor: 7.892

6.  Guidelines for the diagnosis and management of disseminated intravascular coagulation. British Committee for Standards in Haematology.

Authors:  M Levi; C H Toh; J Thachil; H G Watson
Journal:  Br J Haematol       Date:  2009-02-12       Impact factor: 6.998

7.  Thrombelastography-guided blood product use before invasive procedures in cirrhosis with severe coagulopathy: A randomized, controlled trial.

Authors:  Lesley De Pietri; Marcello Bianchini; Roberto Montalti; Nicola De Maria; Tommaso Di Maira; Bruno Begliomini; Giorgio Enrico Gerunda; Fabrizio di Benedetto; Guadalupe Garcia-Tsao; Erica Villa
Journal:  Hepatology       Date:  2015-12-09       Impact factor: 17.425

8.  iTACTIC - implementing Treatment Algorithms for the Correction of Trauma-Induced Coagulopathy: study protocol for a multicentre, randomised controlled trial.

Authors:  Kjersti Baksaas-Aasen; Lewis Gall; Simon Eaglestone; Claire Rourke; Nicole P Juffermans; J Carel Goslings; Paal Aksel Naess; Susan van Dieren; Sisse Rye Ostrowski; Jakob Stensballe; Marc Maegele; Simon J Stanworth; Christine Gaarder; Karim Brohi; Per I Johansson
Journal:  Trials       Date:  2017-10-18       Impact factor: 2.279

9.  Thrombin generation assays for global evaluation of the hemostatic system: perspectives and limitations.

Authors:  Rita Carolina Figueiredo Duarte; Cláudia Natália Ferreira; Danyelle Romana Alves Rios; Helton José Dos Reis; Maria das Graças Carvalho
Journal:  Rev Bras Hematol Hemoter       Date:  2017-05-09

10.  Thrombocytopenia and platelet transfusion in UK critical care: a multicenter observational study.

Authors:  Simon J Stanworth; Timothy S Walsh; Robin J Prescott; Robert J Lee; Douglas M Watson; Duncan L A Wyncoll
Journal:  Transfusion       Date:  2012-08-28       Impact factor: 3.157
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  4 in total

1.  The past, the present, and the future: reflecting on -medical history as we welcome new leaders.

Authors:  Ed Nicol
Journal:  Clin Med (Lond)       Date:  2018-08       Impact factor: 2.659

2.  Risk of major bleeding associated with aspirin use in non-surgical critically ill patients receiving therapeutic anticoagulation.

Authors:  Yosuf W Subat; Hamza Rayes; Andrew C Hanson; Madeline Q Johnson; Phillip J Schulte; Kimberly Evans; Timothy Weister; Vrinda Trivedi; Ognjen Gajic; Matthew A Warner
Journal:  J Crit Care       Date:  2020-04-18       Impact factor: 3.425

3.  Success is the Sum of Small Efforts!

Authors:  Atul P Kulkarni; Srinivas Samavedam; Ashit Hegde
Journal:  Indian J Crit Care Med       Date:  2019-09

4.  Needs and challenges among physicians and researchers in thrombosis and hemostasis: Results from an international study.

Authors:  Suzanne Murray; Claire McLintock; Patrice Lazure; Morgan Peniuta; Sam Schulman; Suely M Rezende; James H Morrissey; Thomas Reiser; Ingrid Pabinger
Journal:  Res Pract Thromb Haemost       Date:  2019-06-28
  4 in total

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