David Bickford1, Ruth T Morin2, Dan Catalinotto1, R Scott Mackin2, J Craig Nelson3. 1. Department of Psychiatry (DB, RTM, DC, RSM, JCN). 2. Department of Psychiatry (DB, RTM, DC, RSM, JCN); University of California, San Francisco, San Francisco, CA; and the San Francisco Veterans Affairs Medical Center (RTM, RSM), San Francisco, CA. 3. Department of Psychiatry (DB, RTM, DC, RSM, JCN). Electronic address: Craig.Nelson@ucsf.edu.
Abstract
OBJECTIVE: Prior work suggests executive dysfunction (ED) on the Stroop Color and Word Test (SCWT) and the Mattis Dementia Rating Scale-2 Initiation/Perseveration subscale (DRS IP) predicts poor antidepressant response in late-life depression. This study examined if either patient perception of ED or the Trail Making Test Part B (TMT-B) could identify patients with impairment on the SCWT or DRS IP. METHODS: Patients were 65 or older and had a diagnosis of major depression without dementia. Cognition was assessed with the TMT-B, the SCWT, and the DRS IP. A self-reported Perceived Deficits Questionnaire (PDQ) subscale assessed patients' perceptions of ED. RESULTS: In 247 participants (mean age 71.3 years), the PDQ subscale was not associated with test performance. The sensitivity of the TMT-B in identifying impairment on the SCWT or DRS IP was low (35% and 23%, respectively). CONCLUSION: Neither the TMT-B nor self-reports are useful screening tools for ED on the SCWT or DRS IP.
OBJECTIVE: Prior work suggests executive dysfunction (ED) on the Stroop Color and Word Test (SCWT) and the Mattis Dementia Rating Scale-2 Initiation/Perseveration subscale (DRS IP) predicts poor antidepressant response in late-life depression. This study examined if either patient perception of ED or the Trail Making Test Part B (TMT-B) could identify patients with impairment on the SCWT or DRS IP. METHODS: Patients were 65 or older and had a diagnosis of major depression without dementia. Cognition was assessed with the TMT-B, the SCWT, and the DRS IP. A self-reported Perceived Deficits Questionnaire (PDQ) subscale assessed patients' perceptions of ED. RESULTS: In 247 participants (mean age 71.3 years), the PDQ subscale was not associated with test performance. The sensitivity of the TMT-B in identifying impairment on the SCWT or DRS IP was low (35% and 23%, respectively). CONCLUSION: Neither the TMT-B nor self-reports are useful screening tools for ED on the SCWT or DRS IP.
Authors: Dawn M Schiehser; Dean C Delis; J Vincent Filoteo; Lisa Delano-Wood; S Duke Han; Amy J Jak; Angela I Drake; Mark W Bondi Journal: J Clin Exp Neuropsychol Date: 2011-07 Impact factor: 2.475
Authors: Monique A Pimontel; David Rindskopf; Bret R Rutherford; Patrick J Brown; Steven P Roose; Joel R Sneed Journal: Am J Geriatr Psychiatry Date: 2015-05-21 Impact factor: 4.105
Authors: Yvette I Sheline; Carl F Pieper; Deanna M Barch; Kathleen Welsh-Bohmer; Kathleen Welsh-Boehmer; Robert C McKinstry; James R MacFall; Gina D'Angelo; Keith S Garcia; Kenneth Gersing; Consuelo Wilkins; Warren Taylor; David C Steffens; Ranga R Krishnan; P Murali Doraiswamy Journal: Arch Gen Psychiatry Date: 2010-03
Authors: Meryl A Butters; Ellen M Whyte; Robert D Nebes; Amy E Begley; Mary Amanda Dew; Benoit H Mulsant; Michelle D Zmuda; Rishi Bhalla; Carolyn Cidis Meltzer; Bruce G Pollock; Charles F Reynolds; James T Becker Journal: Arch Gen Psychiatry Date: 2004-06