| Literature DB >> 30059090 |
Kortney M Kersten1, Meghan E Breen, Anna K Mapp, Adam J Matzger.
Abstract
Antimicrobial functionality is introduced into a pharmaceutical formulation of miconazole while improving solubility. The work leverages hydrate formation propensity in order to produce hydrogen peroxide solvates. The ubiquity of hydrate formation suggests that hydrogen peroxide can be broadly deployed in pharmaceuticals, rendering a liquid excipient suitable for solid pharmaceutical formulations.Entities:
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Year: 2018 PMID: 30059090 PMCID: PMC6163058 DOI: 10.1039/c8cc04530e
Source DB: PubMed Journal: Chem Commun (Camb) ISSN: 1359-7345 Impact factor: 6.222