Literature DB >> 30057509

Constructing an Inexpensive Elevated Plus Maze.

Grant A Fox1, Eugene Torigoe2, Greg Q Butcher1.   

Abstract

Introducing students to the challenges and rewards of legitimate experimentation has become an essential part of many undergraduate lab courses. However, this objective can be difficult to achieve if the students find the topic uninteresting and therefore do not take ownership of the project. Additionally, the budgets of most undergraduate courses do not allow for the purchase of new equipment for student-generated projects. Here we describe a lab project where students engaged in the process of designing and building their own inexpensive apparatus. Driven by their interest in anxiety research, students in a Neuroscience Methods course developed the following protocol to build an elevated plus maze (EPM) and optional data acquisition module, for less than $100 each. The project engaged students in work that required applied critical thinking and real-world problem solving, and produced a functional EPM that was used in multiple projects beyond this course.

Entities:  

Keywords:  Arduino; anxiety; behavioral testing; critical thinking; elevated plus maze (EPM)

Year:  2018        PMID: 30057509      PMCID: PMC6057757     

Source DB:  PubMed          Journal:  J Undergrad Neurosci Educ        ISSN: 1544-2896


  11 in total

1.  Behavioural evaluation of methods for assessing fear responses in weaned pigs.

Authors: 
Journal:  Appl Anim Behav Sci       Date:  2000-10-01       Impact factor: 2.448

2.  Two cone types of rat retina detected by anti-visual pigment antibodies.

Authors:  A Szél; P Röhlich
Journal:  Exp Eye Res       Date:  1992-07       Impact factor: 3.467

3.  The relation between fear induced by novel stimulation and exploratory behavior.

Authors:  K C MONTGOMERY
Journal:  J Comp Physiol Psychol       Date:  1955-08

4.  Effects of alpha-adrenoceptor agonists and antagonists in a maze-exploration model of 'fear'-motivated behaviour.

Authors:  S L Handley; S Mithani
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1984-08       Impact factor: 3.000

5.  The use of a plus-maze to measure anxiety in the mouse.

Authors:  R G Lister
Journal:  Psychopharmacology (Berl)       Date:  1987       Impact factor: 4.530

6.  Validation of open:closed arm entries in an elevated plus-maze as a measure of anxiety in the rat.

Authors:  S Pellow; P Chopin; S E File; M Briley
Journal:  J Neurosci Methods       Date:  1985-08       Impact factor: 2.390

Review 7.  The elevated T-maze as an experimental model of anxiety.

Authors:  F G Graeff; C F Netto; H Zangrossi
Journal:  Neurosci Biobehav Rev       Date:  1998       Impact factor: 8.989

8.  Genetic analyses of the green visual pigments of rabbit (Oryctolagus cuniculus) and rat (Rattus norvegicus).

Authors:  F B Radlwimmer; S Yokoyama
Journal:  Gene       Date:  1998-09-18       Impact factor: 3.688

9.  Behavioural and pharmacological characterisation of the elevated "zero-maze" as an animal model of anxiety.

Authors:  J K Shepherd; S S Grewal; A Fletcher; D J Bill; C T Dourish
Journal:  Psychopharmacology (Berl)       Date:  1994-09       Impact factor: 4.530

10.  Age-dependent relevance of endogenous 5-lipoxygenase derivatives in anxiety-like behavior in mice.

Authors:  Luciana M Leo; Suellen Almeida-Corrêa; Claudio A Canetti; Olavo B Amaral; Fernando A Bozza; Fabricio A Pamplona
Journal:  PLoS One       Date:  2014-01-08       Impact factor: 3.240

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