Literature DB >> 30053337

Comparing Scientific Registry of Transplant Recipients posttransplant program-specific outcome ratings at listing with subsequent recipient outcomes after transplant.

Andrew Wey1, Nicholas Salkowski1, Bertram L Kasiske1,2, Melissa Skeans1, Cory R Schaffhausen2, Sally K Gustafson1, Ajay K Israni1,2,3, Jon J Snyder1,3.   

Abstract

To improve accessibility of program-specific reports to patients, the Scientific Registry of Transplant Recipients released a 5-tier system for categorizing 1-year posttransplant program evaluations. Whether this system predicts subsequent posttransplant outcomes at the time patients are waitlisted has been questioned. We investigated the association of tier at listing and the corresponding continuous score used for tier assignment, which ranges from 0 (poor outcomes) to 1 (good outcomes), with eventual 1-year posttransplant graft survival for candidates listed between July 12, 2011, and June 16, 2014, who underwent transplant before December 31, 2016. One additional tier at listing was associated with better 1-year posttransplant outcomes in liver (hazard ratio [HR], 0.93; 95% confidence interval [CI], 0.89-0.97) and lung transplant (HR, 0.90; 95% CI, 0.84-0.97) but not kidney (HR, 0.96; 95% CI, 0.92-1.01) or heart transplant (HR, 1.02; 95% CI, 0.93-1.10). In liver and lung transplant, longer time between listing and transplant was associated with stronger protective effects for high-tier programs. In kidney, liver, and lung transplant, posttransplant evaluations at listing had nonlinear associations with eventual posttransplant outcomes: relatively flat for 5-tier scores <0.5 and decreasing for scores >0.5. After adjustment for measured recipient and donor risk factors, posttransplant evaluations at listing predicted differences in eventual outcomes in liver and lung transplant, providing useful information to patients.
© 2018 The American Society of Transplantation and the American Society of Transplant Surgeons. This article has been contributed to by US Government employees and their work is in the public domain in the USA.

Entities:  

Keywords:  Scientific Registry for Transplant Recipients (SRTR); health services and outcomes research; organ transplantation in general; statistics

Mesh:

Year:  2018        PMID: 30053337      PMCID: PMC6836690          DOI: 10.1111/ajt.15038

Source DB:  PubMed          Journal:  Am J Transplant        ISSN: 1600-6135            Impact factor:   8.086


  14 in total

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2.  Hospital performance reports: impact on quality, market share, and reputation.

Authors:  Judith H Hibbard; Jean Stockard; Martin Tusler
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Review 3.  Scientific Registry of Transplant Recipients: collecting, analyzing, and reporting data on transplantation in the United States.

Authors:  Susan Leppke; Tabitha Leighton; David Zaun; Shu-Cheng Chen; Melissa Skeans; Ajay K Israni; Jon J Snyder; Bertram L Kasiske
Journal:  Transplant Rev (Orlando)       Date:  2013-03-06       Impact factor: 3.943

4.  Potential Implications of Recent and Proposed Changes in the Regulatory Oversight of Solid Organ Transplantation in the United States.

Authors:  B L Kasiske; N Salkowski; A Wey; A K Israni; J J Snyder
Journal:  Am J Transplant       Date:  2016-07-28       Impact factor: 8.086

5.  What patients and members of their support networks ask about transplant program data.

Authors:  Cory R Schaffhausen; Marilyn J Bruin; Daryl Chesley; Maureen McBride; Jon J Snyder; Bertram L Kasiske; Ajay K Israni
Journal:  Clin Transplant       Date:  2017-10-23       Impact factor: 2.863

6.  The association of center performance evaluations and kidney transplant volume in the United States.

Authors:  J D Schold; L D Buccini; T R Srinivas; R T Srinivas; E D Poggio; S M Flechner; C Soria; D L Segev; J Fung; D A Goldfarb
Journal:  Am J Transplant       Date:  2013-01       Impact factor: 8.086

7.  OPTN/SRTR 2015 Annual Data Report: Liver.

Authors:  W R Kim; J R Lake; J M Smith; M A Skeans; D P Schladt; E B Edwards; A M Harper; J L Wainright; J J Snyder; A K Israni; B L Kasiske
Journal:  Am J Transplant       Date:  2017-01       Impact factor: 8.086

Review 8.  Regulatory oversight in transplantation: are the patients really better off?

Authors:  Thomas E Hamilton
Journal:  Curr Opin Organ Transplant       Date:  2013-04       Impact factor: 2.640

9.  Effects of High-Risk Kidneys on Scientific Registry of Transplant Recipients Program Quality Reports.

Authors:  J J Snyder; N Salkowski; A Wey; A K Israni; J D Schold; D L Segev; B L Kasiske
Journal:  Am J Transplant       Date:  2016-04-05       Impact factor: 8.086

Review 10.  Developing Statistical Models to Assess Transplant Outcomes Using National Registries: The Process in the United States.

Authors:  Jon J Snyder; Nicholas Salkowski; S Joseph Kim; David Zaun; Hui Xiong; Ajay K Israni; Bertram L Kasiske
Journal:  Transplantation       Date:  2016-02       Impact factor: 4.939

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  5 in total

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2.  Significant improvements, but consistent disparities in survival for African Americans after liver transplantation.

Authors:  Stephanie S Keeling; Malcolm F McDonald; Adrish Anand; Greta E Handing; Lyndsey L Prather; Caroline R Christmann; Prasun K Jalal; Fasiha Kanwal; George Cholankeril; John A Goss; Abbas Rana
Journal:  Clin Transplant       Date:  2022-03-25       Impact factor: 3.456

3.  Variation in Racial Disparities in Liver Transplant Outcomes Across Transplant Centers in the United States.

Authors:  Katherine Ross-Driscoll; Michael Kramer; Raymond Lynch; Laura Plantinga; Joel Wedd; Rachel Patzer
Journal:  Liver Transpl       Date:  2020-12-11       Impact factor: 5.799

4.  Comparing Pretransplant and Posttransplant Outcomes When Choosing a Transplant Center: Focus Groups and a Randomized Survey.

Authors:  Cory R Schaffhausen; Marilyn J Bruin; Sauman Chu; Andrew Wey; Warren T McKinney; Jon J Snyder; Jack R Lake; Arthur J Matas; Bertram L Kasiske; Ajay K Israni
Journal:  Transplantation       Date:  2020-01       Impact factor: 5.385

5.  Textbook Outcome as a Quality Metric in Living and Deceased Donor Kidney Transplantation.

Authors:  Austin D Schenk; April J Logan; Jeffrey M Sneddon; Daria Faulkner; Jing L Han; Guy N Brock; William K Washburn
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  5 in total

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