Literature DB >> 3004439

Intracellular Ca2+ requirements for zymosan-stimulated phosphoinositide hydrolysis in mouse peritoneal macrophages.

J Moscat, M Aracil, E Diez, J Balsinde, P Garcia Barreno, A M Municio.   

Abstract

The phosphatidylinositol cycle has been demonstrated to be involved in the control of Ca2+ cytosolic levels in several cellular types. The Ca2+ requirements of phospholipase C activity and the described stimulation of phosphoinositide hydrolysis by Ca2+ ionophores make unclear the relationship between phosphatidylinositol cycle and Ca2+ mobilization. The results reported here suggest that intracellular Ca2+ is necessary for zymosan-stimulated phospholipase C activation in macrophages.

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Year:  1986        PMID： 3004439     DOI： 10.1016/0006-291x(86)90572-3

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  4 in total

1.  Ionophore A23187 induces a refractory state in thrombin-activated release of inositol phosphates.

Authors:  G Moscat; F Moreno; S Iglesias; P Garcia-Barreno; A M Municio
Journal:  Biochem J       Date:  1986-09-15       Impact factor: 3.857

2.  Relationship of phosphatidylinositol bisphosphate hydrolysis to calcium mobilization and functional activation in fluoride-treated neutrophils.

Authors:  D English; D J Debono; T G Gabig
Journal:  J Clin Invest       Date:  1987-07       Impact factor: 14.808

3.  Bacterial lipopolysaccharides prime human neutrophils for enhanced production of leukotriene B4.

Authors:  M E Doerfler; R L Danner; J H Shelhamer; J E Parrillo
Journal:  J Clin Invest       Date:  1989-03       Impact factor: 14.808

4.  Zymosan-induced release of inositol phosphates at resting cytosolic Ca2+ concentrations in macrophages.

Authors:  J Moscat; C Herrero; P Garcia-Barreno; A M Municio
Journal:  Biochem J       Date:  1987-03-01       Impact factor: 3.857
  4 in total

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